Reduced pulmonary inflammatory response during cardiopulmonary bypass: effects of combined pulmonary perfusion and carbon monoxide inhalation.

  • Ulrich Goebel
  • Matthias Siepe
  • Anne Mecklenburg
  • Torsten Doenst
  • Friedhelm Beyersdorf
  • Torsten Loop
  • Christian Schlensak

Related Research units

Abstract

Pulmonary inflammation induced by cardiopulmonary bypass (CPB) is one of the main causes for lung injury after cardiac surgery. Pulmonary perfusions as well as carbon monoxide (CO) inhalation are known to reduce the inflammatory reaction of the lung. We hypothesized that a combination of pulmonary perfusion and carbon monoxide inhalation leads to an even stronger reduction of the lung inflammation.

Bibliographical data

Original languageGerman
Article number6
ISSN1010-7940
Publication statusPublished - 2008
pubmed 18829339