Reduced memory-related ongoing oscillatory activity in healthy older adults

Signe L Winterling; Stephanie M Shields; Michael Rose

doi:10.1016/j.neurobiolaging.2019.03.012

Reduced memory-related ongoing oscillatory activity in healthy older adults

Standard

Reduced memory-related ongoing oscillatory activity in healthy older adults. / Winterling, Signe L; Shields, Stephanie M; Rose, Michael.

In: NEUROBIOL AGING, Vol. 79, 07.2019, p. 1-10.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Winterling, SL, Shields, SM & Rose, M 2019, 'Reduced memory-related ongoing oscillatory activity in healthy older adults', NEUROBIOL AGING, vol. 79, pp. 1-10. https://doi.org/10.1016/j.neurobiolaging.2019.03.012

APA

Winterling, S. L., Shields, S. M., & Rose, M. (2019). Reduced memory-related ongoing oscillatory activity in healthy older adults. NEUROBIOL AGING, 79, 1-10. https://doi.org/10.1016/j.neurobiolaging.2019.03.012

Vancouver

Winterling SL, Shields SM, Rose M. Reduced memory-related ongoing oscillatory activity in healthy older adults. NEUROBIOL AGING. 2019 Jul;79:1-10. https://doi.org/10.1016/j.neurobiolaging.2019.03.012

Bibtex

@article{11874269a9df4d67a9e9ad4d9ce55b5e,

title = "Reduced memory-related ongoing oscillatory activity in healthy older adults",

abstract = "Age-related impairments in episodic memory have been linked to alterations in encoding-induced neural activity. In young individuals, even prestimulus activity has been shown to influence the encoding of an upcoming stimulus, with ongoing theta and beta oscillations being predictive of subsequent recognition. The present study investigated if these memory-related ongoing oscillations are also affected by aging. In an EEG experiment, healthy older and young individuals performed an encoding task with a subsequent recognition test on picture and word stimuli. The group of younger participants showed an increased oscillatory activity in the lower frequency range (ranging from 3 to 17 Hz) in the pre- and post-stimulus period compared with the older adults. Only in young participants, ongoing beta power during encoding was related to later memory in both stimulus categories, whereas in older participants, this effect was diminished. Interestingly, there was no general age-related decrease in recognition performance. These results indicate that ongoing low beta oscillations might constitute a functional indicator of cognitive aging that reveals itself even before a strong decline in behavioral performance is noticeable, and that could be a potential target for neuromodulatory interventions.",

keywords = "Journal Article",

author = "Winterling, {Signe L} and Shields, {Stephanie M} and Michael Rose",

year = "2019",

month = jul,

doi = "10.1016/j.neurobiolaging.2019.03.012",

language = "English",

volume = "79",

pages = "1--10",

journal = "NEUROBIOL AGING",

issn = "0197-4580",

publisher = "Elsevier Inc.",

}

RIS

TY - JOUR

T1 - Reduced memory-related ongoing oscillatory activity in healthy older adults

AU - Winterling, Signe L

AU - Shields, Stephanie M

AU - Rose, Michael

PY - 2019/7

Y1 - 2019/7

N2 - Age-related impairments in episodic memory have been linked to alterations in encoding-induced neural activity. In young individuals, even prestimulus activity has been shown to influence the encoding of an upcoming stimulus, with ongoing theta and beta oscillations being predictive of subsequent recognition. The present study investigated if these memory-related ongoing oscillations are also affected by aging. In an EEG experiment, healthy older and young individuals performed an encoding task with a subsequent recognition test on picture and word stimuli. The group of younger participants showed an increased oscillatory activity in the lower frequency range (ranging from 3 to 17 Hz) in the pre- and post-stimulus period compared with the older adults. Only in young participants, ongoing beta power during encoding was related to later memory in both stimulus categories, whereas in older participants, this effect was diminished. Interestingly, there was no general age-related decrease in recognition performance. These results indicate that ongoing low beta oscillations might constitute a functional indicator of cognitive aging that reveals itself even before a strong decline in behavioral performance is noticeable, and that could be a potential target for neuromodulatory interventions.

AB - Age-related impairments in episodic memory have been linked to alterations in encoding-induced neural activity. In young individuals, even prestimulus activity has been shown to influence the encoding of an upcoming stimulus, with ongoing theta and beta oscillations being predictive of subsequent recognition. The present study investigated if these memory-related ongoing oscillations are also affected by aging. In an EEG experiment, healthy older and young individuals performed an encoding task with a subsequent recognition test on picture and word stimuli. The group of younger participants showed an increased oscillatory activity in the lower frequency range (ranging from 3 to 17 Hz) in the pre- and post-stimulus period compared with the older adults. Only in young participants, ongoing beta power during encoding was related to later memory in both stimulus categories, whereas in older participants, this effect was diminished. Interestingly, there was no general age-related decrease in recognition performance. These results indicate that ongoing low beta oscillations might constitute a functional indicator of cognitive aging that reveals itself even before a strong decline in behavioral performance is noticeable, and that could be a potential target for neuromodulatory interventions.

KW - Journal Article

U2 - 10.1016/j.neurobiolaging.2019.03.012

DO - 10.1016/j.neurobiolaging.2019.03.012

M3 - SCORING: Journal article

C2 - 31026617

VL - 79

SP - 1

EP - 10

JO - NEUROBIOL AGING

JF - NEUROBIOL AGING

SN - 0197-4580

ER -