Redox-generated isoprostanes are associated with residual platelet activity in aspirin-treated patients with stable coronary heart disease.

Abstract

Insufficient platelet inhibition by low-dose aspirin is associated with poor prognosis in patients with coronary heart disease (CHD). We sought to investigate the prevalence of this phenomenon in patients with stable CHD and to study whether oxidative stress plays a role in its pathogenesis.

Bibliographical data

Original languageGerman
Article number12
ISSN1538-7933
Publication statusPublished - 2010
pubmed 20961392