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Recovery from poststroke visual impairment: evidence from a clinical trials resource

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Recovery from poststroke visual impairment: evidence from a clinical trials resource. / Ali, Myzoon; Hazelton, Christine; Lyden, Patrick; Pollock, Alex; Brady, Marian; VISTA Collaboration.

In: NEUROREHAB NEURAL RE, Vol. 27, No. 2, 01.02.2013, p. 133-41.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Ali, M, Hazelton, C, Lyden, P, Pollock, A, Brady, M & VISTA Collaboration 2013, 'Recovery from poststroke visual impairment: evidence from a clinical trials resource', NEUROREHAB NEURAL RE, vol. 27, no. 2, pp. 133-41. https://doi.org/10.1177/1545968312454683

APA

Ali, M., Hazelton, C., Lyden, P., Pollock, A., Brady, M., & VISTA Collaboration (2013). Recovery from poststroke visual impairment: evidence from a clinical trials resource. NEUROREHAB NEURAL RE, 27(2), 133-41. https://doi.org/10.1177/1545968312454683

Vancouver

Ali M, Hazelton C, Lyden P, Pollock A, Brady M, VISTA Collaboration. Recovery from poststroke visual impairment: evidence from a clinical trials resource. NEUROREHAB NEURAL RE. 2013 Feb 1;27(2):133-41. https://doi.org/10.1177/1545968312454683

Bibtex

@article{33cc4ce48d0f45418e3fbc14cbf6eb3d,
title = "Recovery from poststroke visual impairment: evidence from a clinical trials resource",
abstract = "INTRODUCTION: Limited evidence suggests that visual impairments may influence outcome after stroke. The degree of recovery from these impairments is poorly characterized.OBJECTIVES: To describe recovery and to determine whether visual impairments influence functional outcome and quality of life.METHODS: We extracted demographic and outcome data from the Virtual International Stroke Trials Archive (VISTA). We examined horizontal eye movement disorders and hemianopia using the Best Gaze and Visual domains of the National Institutes of Health Stroke Scale (NIHSS) and described recovery at 30 and 90 days. Proportional odds modelling was used to examine the association between impairments at baseline, modified Rankin Scale (mRS), and European Quality of Life Score (EQ-5D) at 90 days.RESULTS: Visual impairments were reported in 7,204/11,900 (60.5%) patients at baseline. Complete recovery occurred in 1,398/3,285 (42.6%) and 3,243/7,204 (45.0%) patients by 30 and 90 days respectively. The burden of persistent visual impairment in survivors was 1,135/4,028 (28.2%) at 30 days and 1,915/9,338 (20.5%) at 90 days. Partial gaze palsy (P < .0001; OR = 0.81; 95% CI = 0.74-0.87), forced deviation (P < .0001; OR = 0.48; 95% CI = 0.43-0.53), and complete homonymous hemianopia (P < .0001; OR = 0.67; 95% CI = 0.62-0.73) at baseline were associated with poor mRS at 90 days.CONCLUSIONS: The rate of recovery was greater in the first month after stroke, suggesting a potential time frame for interventions. The associations between visual impairments and poor mRS suggest that these impairments should be considered in multidisciplinary assessments and interventions.",
keywords = "Female, Follow-Up Studies, Humans, Male, Quality of Life, Recovery of Function, Severity of Illness Index, Stroke, Time Factors, Treatment Outcome, Virtual Reality Exposure Therapy, Vision Disorders",
author = "Myzoon Ali and Christine Hazelton and Patrick Lyden and Alex Pollock and Marian Brady and {VISTA Collaboration} and G{\"o}tz Thomalla",
year = "2013",
month = feb,
day = "1",
doi = "10.1177/1545968312454683",
language = "English",
volume = "27",
pages = "133--41",
journal = "NEUROREHAB NEURAL RE",
issn = "1545-9683",
publisher = "SAGE Publications",
number = "2",

}

RIS

TY - JOUR

T1 - Recovery from poststroke visual impairment: evidence from a clinical trials resource

AU - Ali, Myzoon

AU - Hazelton, Christine

AU - Lyden, Patrick

AU - Pollock, Alex

AU - Brady, Marian

AU - VISTA Collaboration

AU - Thomalla, Götz

PY - 2013/2/1

Y1 - 2013/2/1

N2 - INTRODUCTION: Limited evidence suggests that visual impairments may influence outcome after stroke. The degree of recovery from these impairments is poorly characterized.OBJECTIVES: To describe recovery and to determine whether visual impairments influence functional outcome and quality of life.METHODS: We extracted demographic and outcome data from the Virtual International Stroke Trials Archive (VISTA). We examined horizontal eye movement disorders and hemianopia using the Best Gaze and Visual domains of the National Institutes of Health Stroke Scale (NIHSS) and described recovery at 30 and 90 days. Proportional odds modelling was used to examine the association between impairments at baseline, modified Rankin Scale (mRS), and European Quality of Life Score (EQ-5D) at 90 days.RESULTS: Visual impairments were reported in 7,204/11,900 (60.5%) patients at baseline. Complete recovery occurred in 1,398/3,285 (42.6%) and 3,243/7,204 (45.0%) patients by 30 and 90 days respectively. The burden of persistent visual impairment in survivors was 1,135/4,028 (28.2%) at 30 days and 1,915/9,338 (20.5%) at 90 days. Partial gaze palsy (P < .0001; OR = 0.81; 95% CI = 0.74-0.87), forced deviation (P < .0001; OR = 0.48; 95% CI = 0.43-0.53), and complete homonymous hemianopia (P < .0001; OR = 0.67; 95% CI = 0.62-0.73) at baseline were associated with poor mRS at 90 days.CONCLUSIONS: The rate of recovery was greater in the first month after stroke, suggesting a potential time frame for interventions. The associations between visual impairments and poor mRS suggest that these impairments should be considered in multidisciplinary assessments and interventions.

AB - INTRODUCTION: Limited evidence suggests that visual impairments may influence outcome after stroke. The degree of recovery from these impairments is poorly characterized.OBJECTIVES: To describe recovery and to determine whether visual impairments influence functional outcome and quality of life.METHODS: We extracted demographic and outcome data from the Virtual International Stroke Trials Archive (VISTA). We examined horizontal eye movement disorders and hemianopia using the Best Gaze and Visual domains of the National Institutes of Health Stroke Scale (NIHSS) and described recovery at 30 and 90 days. Proportional odds modelling was used to examine the association between impairments at baseline, modified Rankin Scale (mRS), and European Quality of Life Score (EQ-5D) at 90 days.RESULTS: Visual impairments were reported in 7,204/11,900 (60.5%) patients at baseline. Complete recovery occurred in 1,398/3,285 (42.6%) and 3,243/7,204 (45.0%) patients by 30 and 90 days respectively. The burden of persistent visual impairment in survivors was 1,135/4,028 (28.2%) at 30 days and 1,915/9,338 (20.5%) at 90 days. Partial gaze palsy (P < .0001; OR = 0.81; 95% CI = 0.74-0.87), forced deviation (P < .0001; OR = 0.48; 95% CI = 0.43-0.53), and complete homonymous hemianopia (P < .0001; OR = 0.67; 95% CI = 0.62-0.73) at baseline were associated with poor mRS at 90 days.CONCLUSIONS: The rate of recovery was greater in the first month after stroke, suggesting a potential time frame for interventions. The associations between visual impairments and poor mRS suggest that these impairments should be considered in multidisciplinary assessments and interventions.

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Quality of Life

KW - Recovery of Function

KW - Severity of Illness Index

KW - Stroke

KW - Time Factors

KW - Treatment Outcome

KW - Virtual Reality Exposure Therapy

KW - Vision Disorders

U2 - 10.1177/1545968312454683

DO - 10.1177/1545968312454683

M3 - SCORING: Journal article

C2 - 22961263

VL - 27

SP - 133

EP - 141

JO - NEUROREHAB NEURAL RE

JF - NEUROREHAB NEURAL RE

SN - 1545-9683

IS - 2

ER -