Recent insights into comorbidities in atopic dermatitis

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Recent insights into comorbidities in atopic dermatitis. / Gewiss, Caroline; Augustin, Matthias.

In: EXPERT REV CLIN IMMU, Vol. 19, No. 4, 04.2023, p. 393-404.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{24cc0ff520454790bf3c8d5b7a699176,
title = "Recent insights into comorbidities in atopic dermatitis",
abstract = "INTRODUCTION: The relationship between atopic dermatitis and atopic diseases such as food allergies, asthma, and allergic rhinitis in terms of co-occurrence, underlying mechanisms, and therapy is well documented. There is increasing evidence that atopic dermatitis is associated with non-atopic comorbidities such as cardiac, autoimmune, and neuropsychological comorbidities, as well as cutaneous and extracutaneous infections, establishing atopic dermatitis as a systemic disease.AREAS COVERED: The authors reviewed evidence on atopic and non-atopic comorbidities of atopic dermatitis. A literature search was conducted in PubMed for peer-reviewed articles published until October 2022.EXPERT OPINION: Atopic and non-atopic diseases coexist with atopic dermatitis more often than would be expected by chance. The effect of biologics and small molecules on atopic and non-atopic comorbidities may contribute to a better understanding of the relationship between atopic dermatitis and its comorbidities. Their relationship needs to be explored further to dismantle the underlying mechanism and move toward an atopic dermatitis endotype-based therapeutic approach.",
keywords = "Humans, Dermatitis, Atopic/epidemiology, Comorbidity, Asthma, Rhinitis, Allergic/epidemiology, Food Hypersensitivity",
author = "Caroline Gewiss and Matthias Augustin",
year = "2023",
month = apr,
doi = "10.1080/1744666X.2023.2181790",
language = "English",
volume = "19",
pages = "393--404",
journal = "EXPERT REV CLIN IMMU",
issn = "1744-666X",
publisher = "Taylor and Francis Ltd.",
number = "4",

}

RIS

TY - JOUR

T1 - Recent insights into comorbidities in atopic dermatitis

AU - Gewiss, Caroline

AU - Augustin, Matthias

PY - 2023/4

Y1 - 2023/4

N2 - INTRODUCTION: The relationship between atopic dermatitis and atopic diseases such as food allergies, asthma, and allergic rhinitis in terms of co-occurrence, underlying mechanisms, and therapy is well documented. There is increasing evidence that atopic dermatitis is associated with non-atopic comorbidities such as cardiac, autoimmune, and neuropsychological comorbidities, as well as cutaneous and extracutaneous infections, establishing atopic dermatitis as a systemic disease.AREAS COVERED: The authors reviewed evidence on atopic and non-atopic comorbidities of atopic dermatitis. A literature search was conducted in PubMed for peer-reviewed articles published until October 2022.EXPERT OPINION: Atopic and non-atopic diseases coexist with atopic dermatitis more often than would be expected by chance. The effect of biologics and small molecules on atopic and non-atopic comorbidities may contribute to a better understanding of the relationship between atopic dermatitis and its comorbidities. Their relationship needs to be explored further to dismantle the underlying mechanism and move toward an atopic dermatitis endotype-based therapeutic approach.

AB - INTRODUCTION: The relationship between atopic dermatitis and atopic diseases such as food allergies, asthma, and allergic rhinitis in terms of co-occurrence, underlying mechanisms, and therapy is well documented. There is increasing evidence that atopic dermatitis is associated with non-atopic comorbidities such as cardiac, autoimmune, and neuropsychological comorbidities, as well as cutaneous and extracutaneous infections, establishing atopic dermatitis as a systemic disease.AREAS COVERED: The authors reviewed evidence on atopic and non-atopic comorbidities of atopic dermatitis. A literature search was conducted in PubMed for peer-reviewed articles published until October 2022.EXPERT OPINION: Atopic and non-atopic diseases coexist with atopic dermatitis more often than would be expected by chance. The effect of biologics and small molecules on atopic and non-atopic comorbidities may contribute to a better understanding of the relationship between atopic dermatitis and its comorbidities. Their relationship needs to be explored further to dismantle the underlying mechanism and move toward an atopic dermatitis endotype-based therapeutic approach.

KW - Humans

KW - Dermatitis, Atopic/epidemiology

KW - Comorbidity

KW - Asthma

KW - Rhinitis, Allergic/epidemiology

KW - Food Hypersensitivity

U2 - 10.1080/1744666X.2023.2181790

DO - 10.1080/1744666X.2023.2181790

M3 - SCORING: Review article

C2 - 36796057

VL - 19

SP - 393

EP - 404

JO - EXPERT REV CLIN IMMU

JF - EXPERT REV CLIN IMMU

SN - 1744-666X

IS - 4

ER -