Rapid feature selective neuronal synchronization through correlated latency shifting
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Rapid feature selective neuronal synchronization through correlated latency shifting. / Fries, P; Neuenschwander, S; Engel, A K; Goebel, R; Singer, W.
In: NAT NEUROSCI, Vol. 4, No. 2, 01.02.2001, p. 194-200.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Rapid feature selective neuronal synchronization through correlated latency shifting
AU - Fries, P
AU - Neuenschwander, S
AU - Engel, A K
AU - Goebel, R
AU - Singer, W
PY - 2001/2/1
Y1 - 2001/2/1
N2 - Spontaneous brain activity could affect processing if it were structured. We show that neuron pairs in cat primary visual cortex exhibited correlated fluctuations in response latency, particularly when they had overlapping receptive fields or similar orientation preferences. Correlations occurred within and across hemispheres, but only when local field potentials (LFPs) oscillated in the gamma-frequency range (40-70 Hz). In this range, LFP fluctuations preceding response onset predicted response latencies; negative (positive) LFPs were associated with early (late) responses. Oscillations below 10 Hz caused covariations in response amplitude, but exhibited no columnar selectivity or coordinating effect on latencies. Thus, during high gamma activity, spontaneous activity exhibits distinct, column-specific correlation patterns. Consequently, cortical cells undergo coherent fluctuations in excitability that enhance temporal coherence of responses to contours that are spatially contiguous or have similar orientation. Because synchronized responses are more likely than dispersed responses to undergo rapid and joint processing, spontaneous activity may be important in early visual processes.
AB - Spontaneous brain activity could affect processing if it were structured. We show that neuron pairs in cat primary visual cortex exhibited correlated fluctuations in response latency, particularly when they had overlapping receptive fields or similar orientation preferences. Correlations occurred within and across hemispheres, but only when local field potentials (LFPs) oscillated in the gamma-frequency range (40-70 Hz). In this range, LFP fluctuations preceding response onset predicted response latencies; negative (positive) LFPs were associated with early (late) responses. Oscillations below 10 Hz caused covariations in response amplitude, but exhibited no columnar selectivity or coordinating effect on latencies. Thus, during high gamma activity, spontaneous activity exhibits distinct, column-specific correlation patterns. Consequently, cortical cells undergo coherent fluctuations in excitability that enhance temporal coherence of responses to contours that are spatially contiguous or have similar orientation. Because synchronized responses are more likely than dispersed responses to undergo rapid and joint processing, spontaneous activity may be important in early visual processes.
KW - Action Potentials
KW - Animals
KW - Cats
KW - Cortical Synchronization
KW - Electroencephalography
KW - Macaca mulatta
KW - Neurons
KW - Oscillometry
KW - Photic Stimulation
KW - Reaction Time
KW - Space Perception
KW - Visual Cortex
U2 - 10.1038/84032
DO - 10.1038/84032
M3 - SCORING: Journal article
C2 - 11175881
VL - 4
SP - 194
EP - 200
JO - NAT NEUROSCI
JF - NAT NEUROSCI
SN - 1097-6256
IS - 2
ER -