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Radiofrequency or cryoballoon ablation for index pulmonary vein isolation: What is the impact on long-term clinical outcomes after repeat ablation?

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Radiofrequency or cryoballoon ablation for index pulmonary vein isolation: What is the impact on long-term clinical outcomes after repeat ablation? / Inaba, Osamu; Metzner, Andreas; Rottner, Laura; Mathew, Shibu; Lemes, Christine; Maurer, Tilman; Heeger, Christian; John, Alexander; Hashiguchi, Naotaka; Wohlmuth, Peter; Ouyang, Feifan; Kuck, Karl-Heinz; Rillig, Andreas; Reissmann, Bruno.

In: J CARDIOVASC ELECTR, Vol. 31, No. 5, 01.05.2020, p. 1068-1074.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Inaba, O, Metzner, A, Rottner, L, Mathew, S, Lemes, C, Maurer, T, Heeger, C, John, A, Hashiguchi, N, Wohlmuth, P, Ouyang, F, Kuck, K-H, Rillig, A & Reissmann, B 2020, 'Radiofrequency or cryoballoon ablation for index pulmonary vein isolation: What is the impact on long-term clinical outcomes after repeat ablation?', J CARDIOVASC ELECTR, vol. 31, no. 5, pp. 1068-1074. https://doi.org/10.1111/jce.14432

APA

Inaba, O., Metzner, A., Rottner, L., Mathew, S., Lemes, C., Maurer, T., Heeger, C., John, A., Hashiguchi, N., Wohlmuth, P., Ouyang, F., Kuck, K-H., Rillig, A., & Reissmann, B. (2020). Radiofrequency or cryoballoon ablation for index pulmonary vein isolation: What is the impact on long-term clinical outcomes after repeat ablation? J CARDIOVASC ELECTR, 31(5), 1068-1074. https://doi.org/10.1111/jce.14432

Vancouver

Inaba O, Metzner A, Rottner L, Mathew S, Lemes C, Maurer T et al. Radiofrequency or cryoballoon ablation for index pulmonary vein isolation: What is the impact on long-term clinical outcomes after repeat ablation? J CARDIOVASC ELECTR. 2020 May 1;31(5):1068-1074. https://doi.org/10.1111/jce.14432

Bibtex

@article{a21d827cee324caf91a8cb665b624094,
title = "Radiofrequency or cryoballoon ablation for index pulmonary vein isolation: What is the impact on long-term clinical outcomes after repeat ablation?",
abstract = "AIMS: The current study sought to assess the impact of the utilized energy source during index ablation on long-term clinical outcomes after repeat ablation of atrial fibrillation (AF). Index ablation procedures were either performed using radiofrequency current (RFC) (RFC group) or cryoballoon (CB) ablation (CB group). Repeat ablation was performed by the use of RFC.METHODS: A total of 195 patients (138 RFC group; 57 CB group) with paroxysmal AF were included. All patients had a recurrence of AF following the index ablation procedure. Freedom from AF was estimated with the Kaplan-Meier method.RESULTS: After a 3 years follow-up, the estimated arrhythmia-free survival did not differ between the two groups (RFC group 48% vs CB group 47%, P = .78). During index ablation, procedure times were significantly shorter in the CB group (95 [80, 140] vs 140 [115, 164] minutes, P ≤ .001), whereas fluoroscopy times (16 [11; 22] vs 19 [14; 25] minutes, P = .003), the dose area product (1862 [1203; 2922] vs 3148 [1756; 5888] cGycm2 , P ≤ .001) and the amount of contrast dye (92 ± 32 vs 123 ± 33 mL, P ≤ .001) were significantly lower in the RFC group. During repeat ablation, procedure times were significantly shorter in patients being initially treated with RFC (115 [85; 145] vs 125 [105; 150] minutes, P = .007). There was a trend towards a higher pulmonary vein reconnection rate in the RFC group without meeting statistical significance (P = .074).CONCLUSIONS: In patients with repeat ablation of AF, index RFC or CB ablation are equally effective in terms of freedom from AF. Although CB ablation results in shorter index procedures times, durations of repeat ablation are significantly longer.",
keywords = "Action Potentials, Aged, Atrial Fibrillation/diagnosis, Catheter Ablation/adverse effects, Cryosurgery/adverse effects, Disease-Free Survival, Female, Heart Rate, Humans, Male, Middle Aged, Pulmonary Veins/physiopathology, Recurrence, Reoperation, Retrospective Studies, Risk Assessment, Risk Factors, Time Factors",
author = "Osamu Inaba and Andreas Metzner and Laura Rottner and Shibu Mathew and Christine Lemes and Tilman Maurer and Christian Heeger and Alexander John and Naotaka Hashiguchi and Peter Wohlmuth and Feifan Ouyang and Karl-Heinz Kuck and Andreas Rillig and Bruno Reissmann",
note = "{\textcopyright} 2020 The Authors. Journal of Cardiovascular Electrophysiology published by Wiley Periodicals, Inc.",
year = "2020",
month = may,
day = "1",
doi = "10.1111/jce.14432",
language = "English",
volume = "31",
pages = "1068--1074",
journal = "J CARDIOVASC ELECTR",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Radiofrequency or cryoballoon ablation for index pulmonary vein isolation: What is the impact on long-term clinical outcomes after repeat ablation?

AU - Inaba, Osamu

AU - Metzner, Andreas

AU - Rottner, Laura

AU - Mathew, Shibu

AU - Lemes, Christine

AU - Maurer, Tilman

AU - Heeger, Christian

AU - John, Alexander

AU - Hashiguchi, Naotaka

AU - Wohlmuth, Peter

AU - Ouyang, Feifan

AU - Kuck, Karl-Heinz

AU - Rillig, Andreas

AU - Reissmann, Bruno

N1 - © 2020 The Authors. Journal of Cardiovascular Electrophysiology published by Wiley Periodicals, Inc.

PY - 2020/5/1

Y1 - 2020/5/1

N2 - AIMS: The current study sought to assess the impact of the utilized energy source during index ablation on long-term clinical outcomes after repeat ablation of atrial fibrillation (AF). Index ablation procedures were either performed using radiofrequency current (RFC) (RFC group) or cryoballoon (CB) ablation (CB group). Repeat ablation was performed by the use of RFC.METHODS: A total of 195 patients (138 RFC group; 57 CB group) with paroxysmal AF were included. All patients had a recurrence of AF following the index ablation procedure. Freedom from AF was estimated with the Kaplan-Meier method.RESULTS: After a 3 years follow-up, the estimated arrhythmia-free survival did not differ between the two groups (RFC group 48% vs CB group 47%, P = .78). During index ablation, procedure times were significantly shorter in the CB group (95 [80, 140] vs 140 [115, 164] minutes, P ≤ .001), whereas fluoroscopy times (16 [11; 22] vs 19 [14; 25] minutes, P = .003), the dose area product (1862 [1203; 2922] vs 3148 [1756; 5888] cGycm2 , P ≤ .001) and the amount of contrast dye (92 ± 32 vs 123 ± 33 mL, P ≤ .001) were significantly lower in the RFC group. During repeat ablation, procedure times were significantly shorter in patients being initially treated with RFC (115 [85; 145] vs 125 [105; 150] minutes, P = .007). There was a trend towards a higher pulmonary vein reconnection rate in the RFC group without meeting statistical significance (P = .074).CONCLUSIONS: In patients with repeat ablation of AF, index RFC or CB ablation are equally effective in terms of freedom from AF. Although CB ablation results in shorter index procedures times, durations of repeat ablation are significantly longer.

AB - AIMS: The current study sought to assess the impact of the utilized energy source during index ablation on long-term clinical outcomes after repeat ablation of atrial fibrillation (AF). Index ablation procedures were either performed using radiofrequency current (RFC) (RFC group) or cryoballoon (CB) ablation (CB group). Repeat ablation was performed by the use of RFC.METHODS: A total of 195 patients (138 RFC group; 57 CB group) with paroxysmal AF were included. All patients had a recurrence of AF following the index ablation procedure. Freedom from AF was estimated with the Kaplan-Meier method.RESULTS: After a 3 years follow-up, the estimated arrhythmia-free survival did not differ between the two groups (RFC group 48% vs CB group 47%, P = .78). During index ablation, procedure times were significantly shorter in the CB group (95 [80, 140] vs 140 [115, 164] minutes, P ≤ .001), whereas fluoroscopy times (16 [11; 22] vs 19 [14; 25] minutes, P = .003), the dose area product (1862 [1203; 2922] vs 3148 [1756; 5888] cGycm2 , P ≤ .001) and the amount of contrast dye (92 ± 32 vs 123 ± 33 mL, P ≤ .001) were significantly lower in the RFC group. During repeat ablation, procedure times were significantly shorter in patients being initially treated with RFC (115 [85; 145] vs 125 [105; 150] minutes, P = .007). There was a trend towards a higher pulmonary vein reconnection rate in the RFC group without meeting statistical significance (P = .074).CONCLUSIONS: In patients with repeat ablation of AF, index RFC or CB ablation are equally effective in terms of freedom from AF. Although CB ablation results in shorter index procedures times, durations of repeat ablation are significantly longer.

KW - Action Potentials

KW - Aged

KW - Atrial Fibrillation/diagnosis

KW - Catheter Ablation/adverse effects

KW - Cryosurgery/adverse effects

KW - Disease-Free Survival

KW - Female

KW - Heart Rate

KW - Humans

KW - Male

KW - Middle Aged

KW - Pulmonary Veins/physiopathology

KW - Recurrence

KW - Reoperation

KW - Retrospective Studies

KW - Risk Assessment

KW - Risk Factors

KW - Time Factors

U2 - 10.1111/jce.14432

DO - 10.1111/jce.14432

M3 - SCORING: Journal article

C2 - 32128924

VL - 31

SP - 1068

EP - 1074

JO - J CARDIOVASC ELECTR

JF - J CARDIOVASC ELECTR

SN - 1045-3873

IS - 5

ER -