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Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study

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Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study. / Schrage, Benedikt; Seiffert, Moritz; Müllerleile, Kai; Zengin, Elvin; Lubos, Edith; Sinning, Christoph; Schäfer, Ulrich; Sydow, Karsten; Blankenberg, Stefan; Westermann, Dirk.

In: MINERVA CARDIOANGIOL , Vol. 65, No. 1, 02.2017, p. 1-7.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schrage, B, Seiffert, M, Müllerleile, K, Zengin, E, Lubos, E, Sinning, C, Schäfer, U, Sydow, K, Blankenberg, S & Westermann, D 2017, 'Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study', MINERVA CARDIOANGIOL , vol. 65, no. 1, pp. 1-7. https://doi.org/10.23736/S0026-4725.16.04072-X

APA

Schrage, B., Seiffert, M., Müllerleile, K., Zengin, E., Lubos, E., Sinning, C., Schäfer, U., Sydow, K., Blankenberg, S., & Westermann, D. (2017). Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study. MINERVA CARDIOANGIOL , 65(1), 1-7. https://doi.org/10.23736/S0026-4725.16.04072-X

Vancouver

Schrage B, Seiffert M, Müllerleile K, Zengin E, Lubos E, Sinning C et al. Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study. MINERVA CARDIOANGIOL . 2017 Feb;65(1):1-7. https://doi.org/10.23736/S0026-4725.16.04072-X

Bibtex

@article{dcd27ec8898d4732a50d7cd65bbee740,
title = "Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study",
abstract = "BACKGROUND: Bioabsorbable vascular scaffolds (BVS) are a novel option for the treatment of coronary lesions in patients with stable coronary artery disease or acute coronary syndromes. We aimed to identify the influence of BVS implantation on radiation exposure and procedural outcomes compared to drug-eluting stents (DES) in daily clinical practice.METHODS: A retrospective single-center study was performed in patients undergoing percutaneous coronary intervention with BVS from 2013 to 2014. Only patients with exclusive BVS implantation (N.=78 procedures) were compared with a 2:1 matched cohort of exclusive DES-treated patients in the same period (N.=156 procedures). We used a four-step protocol to reduce radiation exposure in all procedures. Furthermore, a 12-month clinical follow-up was performed.RESULTS: Patients had similar baseline characteristics due to matching. Radiation exposure (1826 vs. 2167 cGy*cm2, P=0.673), procedure time (73 vs. 65 minutes, P=0.574), target vessel revascularization (1.3 vs. 1.3%, p=1.000 for PCI; 1.3 vs. 0.6%, P=0.616 for CABG), cardiovascular death (0.0 vs. 2.6%, P=0.304) or all-cause death (0.0 vs. 3.2%, P=0.172) were similar after implantation of BVS vs. DES. However, exposure to contrast agent (166 vs. 139 mL, P=0.028) was significantly higher in the BVS group.CONCLUSIONS: The implantation of BVS in combination with a simple four-step protocol is a feasible option for interventional treatment of non-complex coronary lesions without significant impact on radiation exposure or outcome measures in daily clinical routine.",
keywords = "Absorbable Implants, Aged, Blood Vessel Prosthesis, Cohort Studies, Coronary Artery Disease/mortality, Drug-Eluting Stents, Female, Follow-Up Studies, Humans, Male, Middle Aged, Percutaneous Coronary Intervention, Radiation Exposure/adverse effects, Retrospective Studies, Treatment Outcome",
author = "Benedikt Schrage and Moritz Seiffert and Kai M{\"u}llerleile and Elvin Zengin and Edith Lubos and Christoph Sinning and Ulrich Sch{\"a}fer and Karsten Sydow and Stefan Blankenberg and Dirk Westermann",
year = "2017",
month = feb,
doi = "10.23736/S0026-4725.16.04072-X",
language = "English",
volume = "65",
pages = "1--7",
journal = "MINERVA CARDIOANGIOL ",
issn = "0026-4725",
publisher = "Edizioni Minerva Medica S.p.A.",
number = "1",

}

RIS

TY - JOUR

T1 - Radiation exposure during the implantation of bioabsorbable vascular scaffolds versus drug-eluting stents in non-complex coronary lesions: a matched-cohort study

AU - Schrage, Benedikt

AU - Seiffert, Moritz

AU - Müllerleile, Kai

AU - Zengin, Elvin

AU - Lubos, Edith

AU - Sinning, Christoph

AU - Schäfer, Ulrich

AU - Sydow, Karsten

AU - Blankenberg, Stefan

AU - Westermann, Dirk

PY - 2017/2

Y1 - 2017/2

N2 - BACKGROUND: Bioabsorbable vascular scaffolds (BVS) are a novel option for the treatment of coronary lesions in patients with stable coronary artery disease or acute coronary syndromes. We aimed to identify the influence of BVS implantation on radiation exposure and procedural outcomes compared to drug-eluting stents (DES) in daily clinical practice.METHODS: A retrospective single-center study was performed in patients undergoing percutaneous coronary intervention with BVS from 2013 to 2014. Only patients with exclusive BVS implantation (N.=78 procedures) were compared with a 2:1 matched cohort of exclusive DES-treated patients in the same period (N.=156 procedures). We used a four-step protocol to reduce radiation exposure in all procedures. Furthermore, a 12-month clinical follow-up was performed.RESULTS: Patients had similar baseline characteristics due to matching. Radiation exposure (1826 vs. 2167 cGy*cm2, P=0.673), procedure time (73 vs. 65 minutes, P=0.574), target vessel revascularization (1.3 vs. 1.3%, p=1.000 for PCI; 1.3 vs. 0.6%, P=0.616 for CABG), cardiovascular death (0.0 vs. 2.6%, P=0.304) or all-cause death (0.0 vs. 3.2%, P=0.172) were similar after implantation of BVS vs. DES. However, exposure to contrast agent (166 vs. 139 mL, P=0.028) was significantly higher in the BVS group.CONCLUSIONS: The implantation of BVS in combination with a simple four-step protocol is a feasible option for interventional treatment of non-complex coronary lesions without significant impact on radiation exposure or outcome measures in daily clinical routine.

AB - BACKGROUND: Bioabsorbable vascular scaffolds (BVS) are a novel option for the treatment of coronary lesions in patients with stable coronary artery disease or acute coronary syndromes. We aimed to identify the influence of BVS implantation on radiation exposure and procedural outcomes compared to drug-eluting stents (DES) in daily clinical practice.METHODS: A retrospective single-center study was performed in patients undergoing percutaneous coronary intervention with BVS from 2013 to 2014. Only patients with exclusive BVS implantation (N.=78 procedures) were compared with a 2:1 matched cohort of exclusive DES-treated patients in the same period (N.=156 procedures). We used a four-step protocol to reduce radiation exposure in all procedures. Furthermore, a 12-month clinical follow-up was performed.RESULTS: Patients had similar baseline characteristics due to matching. Radiation exposure (1826 vs. 2167 cGy*cm2, P=0.673), procedure time (73 vs. 65 minutes, P=0.574), target vessel revascularization (1.3 vs. 1.3%, p=1.000 for PCI; 1.3 vs. 0.6%, P=0.616 for CABG), cardiovascular death (0.0 vs. 2.6%, P=0.304) or all-cause death (0.0 vs. 3.2%, P=0.172) were similar after implantation of BVS vs. DES. However, exposure to contrast agent (166 vs. 139 mL, P=0.028) was significantly higher in the BVS group.CONCLUSIONS: The implantation of BVS in combination with a simple four-step protocol is a feasible option for interventional treatment of non-complex coronary lesions without significant impact on radiation exposure or outcome measures in daily clinical routine.

KW - Absorbable Implants

KW - Aged

KW - Blood Vessel Prosthesis

KW - Cohort Studies

KW - Coronary Artery Disease/mortality

KW - Drug-Eluting Stents

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Percutaneous Coronary Intervention

KW - Radiation Exposure/adverse effects

KW - Retrospective Studies

KW - Treatment Outcome

U2 - 10.23736/S0026-4725.16.04072-X

DO - 10.23736/S0026-4725.16.04072-X

M3 - SCORING: Journal article

C2 - 27249788

VL - 65

SP - 1

EP - 7

JO - MINERVA CARDIOANGIOL

JF - MINERVA CARDIOANGIOL

SN - 0026-4725

IS - 1

ER -