Quantitative Sensory Testing in adults with Autism Spectrum Disorders
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Quantitative Sensory Testing in adults with Autism Spectrum Disorders. / Fründt, Odette; Grashorn, Wiebke; Schöttle, Daniel; Peiker, Ina; David, Nicole; Engel, Andreas K; Forkmann, Katarina; Wrobel, Nathalie; Münchau, Alexander; Bingel, Ulrike.
In: J AUTISM DEV DISORD, Vol. 47, No. 4, 04.2017, p. 1183-1192.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Quantitative Sensory Testing in adults with Autism Spectrum Disorders
AU - Fründt, Odette
AU - Grashorn, Wiebke
AU - Schöttle, Daniel
AU - Peiker, Ina
AU - David, Nicole
AU - Engel, Andreas K
AU - Forkmann, Katarina
AU - Wrobel, Nathalie
AU - Münchau, Alexander
AU - Bingel, Ulrike
PY - 2017/4
Y1 - 2017/4
N2 - Altered sensory perception has been found in patients with autism spectrum disorders (ASD) and might be related to aberrant sensory perception thresholds. We used the well-established, standardized Quantitative sensory testing (QST) protocol of the German Research Network on Neuropathic Pain to investigate 13 somatosensory parameters including thermal and tactile detection and pain thresholds in 13 ASD adults and 13 matched healthy controls with normal IQ values. There were no group differences between somatosensory detection and pain thresholds. Two ASD patients showed paradoxical heat sensations and another two ASD subjects presented dynamic mechanical allodynia; somatosensory features that were absent in controls. These findings suggest that central mechanisms during complex stimulus integration rather than peripheral dysfunctions probably determine somatosensory alterations in ASD.
AB - Altered sensory perception has been found in patients with autism spectrum disorders (ASD) and might be related to aberrant sensory perception thresholds. We used the well-established, standardized Quantitative sensory testing (QST) protocol of the German Research Network on Neuropathic Pain to investigate 13 somatosensory parameters including thermal and tactile detection and pain thresholds in 13 ASD adults and 13 matched healthy controls with normal IQ values. There were no group differences between somatosensory detection and pain thresholds. Two ASD patients showed paradoxical heat sensations and another two ASD subjects presented dynamic mechanical allodynia; somatosensory features that were absent in controls. These findings suggest that central mechanisms during complex stimulus integration rather than peripheral dysfunctions probably determine somatosensory alterations in ASD.
U2 - 10.1007/s10803-017-3041-4
DO - 10.1007/s10803-017-3041-4
M3 - SCORING: Journal article
C2 - 28160223
VL - 47
SP - 1183
EP - 1192
JO - J AUTISM DEV DISORD
JF - J AUTISM DEV DISORD
SN - 0162-3257
IS - 4
ER -