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Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients

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Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients. / Saugel, Bernd; Wildgruber, Moritz; Staudt, Albrecht; Dieckmeyer, Michael; Holzapfel, Konstantin; Kaissis, Georgios; Kirov, Mikhail Y; Kuzkov, Vsevolod V; Schmid, Roland M; Huber, Wolfgang.

In: J CLIN MONIT COMPUT, Vol. 33, No. 1, 02.2019, p. 5-12.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Saugel, B, Wildgruber, M, Staudt, A, Dieckmeyer, M, Holzapfel, K, Kaissis, G, Kirov, MY, Kuzkov, VV, Schmid, RM & Huber, W 2019, 'Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients', J CLIN MONIT COMPUT, vol. 33, no. 1, pp. 5-12. https://doi.org/10.1007/s10877-018-0144-1

APA

Saugel, B., Wildgruber, M., Staudt, A., Dieckmeyer, M., Holzapfel, K., Kaissis, G., Kirov, M. Y., Kuzkov, V. V., Schmid, R. M., & Huber, W. (2019). Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients. J CLIN MONIT COMPUT, 33(1), 5-12. https://doi.org/10.1007/s10877-018-0144-1

Vancouver

Saugel B, Wildgruber M, Staudt A, Dieckmeyer M, Holzapfel K, Kaissis G et al. Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients. J CLIN MONIT COMPUT. 2019 Feb;33(1):5-12. https://doi.org/10.1007/s10877-018-0144-1

Bibtex

@article{a2d6c0a4c5f64898a4e7c5feee4e102d,
title = "Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients",
abstract = "Extravascular lung water (index) (EVLW(I)) can be estimated using transpulmonary thermodilution (TPTD). Computed tomography (CT) with quantitative analysis of lung tissue density has been proposed to quantify pulmonary edema. We compared variables of pulmonary fluid status assessed using quantitative CT and TPTD in critically ill patients. In 21 intensive care unit patients, we performed TPTD measurements directly before and after chest CT. Based on the density data of segmented CT images we calculated the tissue volume (TV), tissue volume index (TVI), and the mean weighted index of voxel aqueous density (VMWaq). CT-derived TV, TVI, and VMWaq did not predict TPTD-derived EVLWI values ≥ 14 mL/kg. There was a significant moderate positive correlation between VMWaq and mean EVLWI (EVLWI before and after CT) (r = 0.45, p = 0.042) and EVLWI after CT (r = 0.49, p = 0.025) but not EVLWI before CT (r = 0.38, p = 0.086). There was no significant correlation between TV and EVLW before CT, EVLW after CT, or mean EVLW. There was no significant correlation between TVI and EVLWI before CT, EVLWI after CT, or mean EVLWI. CT-derived variables did not predict elevated TPTD-derived EVLWI values. In unselected critically ill patients, variables of pulmonary fluid status assessed using quantitative CT cannot be used to predict EVLWI.",
keywords = "Journal Article",
author = "Bernd Saugel and Moritz Wildgruber and Albrecht Staudt and Michael Dieckmeyer and Konstantin Holzapfel and Georgios Kaissis and Kirov, {Mikhail Y} and Kuzkov, {Vsevolod V} and Schmid, {Roland M} and Wolfgang Huber",
year = "2019",
month = feb,
doi = "10.1007/s10877-018-0144-1",
language = "English",
volume = "33",
pages = "5--12",
journal = "J CLIN MONIT COMPUT",
issn = "1387-1307",
publisher = "Springer Netherlands",
number = "1",

}

RIS

TY - JOUR

T1 - Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients

AU - Saugel, Bernd

AU - Wildgruber, Moritz

AU - Staudt, Albrecht

AU - Dieckmeyer, Michael

AU - Holzapfel, Konstantin

AU - Kaissis, Georgios

AU - Kirov, Mikhail Y

AU - Kuzkov, Vsevolod V

AU - Schmid, Roland M

AU - Huber, Wolfgang

PY - 2019/2

Y1 - 2019/2

N2 - Extravascular lung water (index) (EVLW(I)) can be estimated using transpulmonary thermodilution (TPTD). Computed tomography (CT) with quantitative analysis of lung tissue density has been proposed to quantify pulmonary edema. We compared variables of pulmonary fluid status assessed using quantitative CT and TPTD in critically ill patients. In 21 intensive care unit patients, we performed TPTD measurements directly before and after chest CT. Based on the density data of segmented CT images we calculated the tissue volume (TV), tissue volume index (TVI), and the mean weighted index of voxel aqueous density (VMWaq). CT-derived TV, TVI, and VMWaq did not predict TPTD-derived EVLWI values ≥ 14 mL/kg. There was a significant moderate positive correlation between VMWaq and mean EVLWI (EVLWI before and after CT) (r = 0.45, p = 0.042) and EVLWI after CT (r = 0.49, p = 0.025) but not EVLWI before CT (r = 0.38, p = 0.086). There was no significant correlation between TV and EVLW before CT, EVLW after CT, or mean EVLW. There was no significant correlation between TVI and EVLWI before CT, EVLWI after CT, or mean EVLWI. CT-derived variables did not predict elevated TPTD-derived EVLWI values. In unselected critically ill patients, variables of pulmonary fluid status assessed using quantitative CT cannot be used to predict EVLWI.

AB - Extravascular lung water (index) (EVLW(I)) can be estimated using transpulmonary thermodilution (TPTD). Computed tomography (CT) with quantitative analysis of lung tissue density has been proposed to quantify pulmonary edema. We compared variables of pulmonary fluid status assessed using quantitative CT and TPTD in critically ill patients. In 21 intensive care unit patients, we performed TPTD measurements directly before and after chest CT. Based on the density data of segmented CT images we calculated the tissue volume (TV), tissue volume index (TVI), and the mean weighted index of voxel aqueous density (VMWaq). CT-derived TV, TVI, and VMWaq did not predict TPTD-derived EVLWI values ≥ 14 mL/kg. There was a significant moderate positive correlation between VMWaq and mean EVLWI (EVLWI before and after CT) (r = 0.45, p = 0.042) and EVLWI after CT (r = 0.49, p = 0.025) but not EVLWI before CT (r = 0.38, p = 0.086). There was no significant correlation between TV and EVLW before CT, EVLW after CT, or mean EVLW. There was no significant correlation between TVI and EVLWI before CT, EVLWI after CT, or mean EVLWI. CT-derived variables did not predict elevated TPTD-derived EVLWI values. In unselected critically ill patients, variables of pulmonary fluid status assessed using quantitative CT cannot be used to predict EVLWI.

KW - Journal Article

U2 - 10.1007/s10877-018-0144-1

DO - 10.1007/s10877-018-0144-1

M3 - SCORING: Journal article

C2 - 29680878

VL - 33

SP - 5

EP - 12

JO - J CLIN MONIT COMPUT

JF - J CLIN MONIT COMPUT

SN - 1387-1307

IS - 1

ER -