Quantification of relative biological effectiveness, dose modification factor and therapeutic gain factor.

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Quantification of relative biological effectiveness, dose modification factor and therapeutic gain factor. / Beck-Bornholdt, Hans-Peter.

In: STRAHLENTHER ONKOL, Vol. 169, No. 1, 1, 1993, p. 42-47.

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@article{a90357b4c8b8434bbf7461a41700bc08,
title = "Quantification of relative biological effectiveness, dose modification factor and therapeutic gain factor.",
abstract = "Some basic aspects of tumor cell radiobiology are reviewed and the classical methods for the quantification of tumor response are outlined. The definition and methods for quantification of the parameters {"}relative biological effectiveness{"}, {"}dose modification factor{"}, and {"}therapeutic gain factor{"} are discussed. It is concluded that the first two parameters are of little practical use to compare different treatments. Only the therapeutic gain factor enables a reasonable estimation of the benefit that can be obtained from a new treatment modality.",
author = "Hans-Peter Beck-Bornholdt",
year = "1993",
language = "Deutsch",
volume = "169",
pages = "42--47",
journal = "STRAHLENTHER ONKOL",
issn = "0179-7158",
publisher = "Urban und Vogel",
number = "1",

}

RIS

TY - JOUR

T1 - Quantification of relative biological effectiveness, dose modification factor and therapeutic gain factor.

AU - Beck-Bornholdt, Hans-Peter

PY - 1993

Y1 - 1993

N2 - Some basic aspects of tumor cell radiobiology are reviewed and the classical methods for the quantification of tumor response are outlined. The definition and methods for quantification of the parameters "relative biological effectiveness", "dose modification factor", and "therapeutic gain factor" are discussed. It is concluded that the first two parameters are of little practical use to compare different treatments. Only the therapeutic gain factor enables a reasonable estimation of the benefit that can be obtained from a new treatment modality.

AB - Some basic aspects of tumor cell radiobiology are reviewed and the classical methods for the quantification of tumor response are outlined. The definition and methods for quantification of the parameters "relative biological effectiveness", "dose modification factor", and "therapeutic gain factor" are discussed. It is concluded that the first two parameters are of little practical use to compare different treatments. Only the therapeutic gain factor enables a reasonable estimation of the benefit that can be obtained from a new treatment modality.

M3 - SCORING: Zeitschriftenaufsatz

VL - 169

SP - 42

EP - 47

JO - STRAHLENTHER ONKOL

JF - STRAHLENTHER ONKOL

SN - 0179-7158

IS - 1

M1 - 1

ER -