Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS)
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Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS) : prospects for a feedback mechanism for surgical laser systems. / Kanawade, Rajesh; Mahari, Fanuel; Klämpfl, Florian; Rohde, Maximilian; Knipfer, Christian; Tangermann-Gerk, Katja; Adler, Werner; Schmidt, Michael; Stelzle, Florian.
In: J BIOPHOTONICS, Vol. 8, No. 1-2, 01.2015, p. 153-61.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS)
T2 - prospects for a feedback mechanism for surgical laser systems
AU - Kanawade, Rajesh
AU - Mahari, Fanuel
AU - Klämpfl, Florian
AU - Rohde, Maximilian
AU - Knipfer, Christian
AU - Tangermann-Gerk, Katja
AU - Adler, Werner
AU - Schmidt, Michael
AU - Stelzle, Florian
N1 - © 2015 The Authors. Journal of Biophotonics published by WILEY-VCH Verlag.
PY - 2015/1
Y1 - 2015/1
N2 - The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'Laser Induced Breakdown Spectroscopy' (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback control mechanism for clinical laser surgery systems during the laser ablation process. Ex-vivo domestic pig tissue samples (muscle, fat, nerve and skin) were used in this experiment. Atomic emission intensity ratios were analyzed to find a characteristic spectral line for each tissue. The results showed characteristic elemental emission intensity ratios for the respective tissues. The spectral lines and intensity ratios of these specific elements varied among the different tissue types. The main goal of this study is to qualitatively and precisely identify different tissue types for tissue specific laser surgery.
AB - The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'Laser Induced Breakdown Spectroscopy' (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback control mechanism for clinical laser surgery systems during the laser ablation process. Ex-vivo domestic pig tissue samples (muscle, fat, nerve and skin) were used in this experiment. Atomic emission intensity ratios were analyzed to find a characteristic spectral line for each tissue. The results showed characteristic elemental emission intensity ratios for the respective tissues. The spectral lines and intensity ratios of these specific elements varied among the different tissue types. The main goal of this study is to qualitatively and precisely identify different tissue types for tissue specific laser surgery.
KW - Animals
KW - Feedback
KW - Laser Therapy
KW - Organ Specificity
KW - Spectrum Analysis
KW - Swine
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1002/jbio.201300159
DO - 10.1002/jbio.201300159
M3 - SCORING: Journal article
C2 - 24376030
VL - 8
SP - 153
EP - 161
JO - J BIOPHOTONICS
JF - J BIOPHOTONICS
SN - 1864-063X
IS - 1-2
ER -
