Putting the spotlight on donation-related risks and donor safety - are we succeeding in protecting donors?
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Putting the spotlight on donation-related risks and donor safety - are we succeeding in protecting donors? / Mikkelsen, Christina; Mori, Gaia; van Walraven, Suzanna M; Castrén, Johanna; Zahra, Sharon; MacLennan, Sheila; Seidel, Kirsten; Fontana, Stefano; Veropalumbo, Eva; Cannata, Livia; Pupella, Simonetta; Kvist, Maria; Happel, Marjan; Korkalainen, Piia; Wulff, Birgit; Fernandez-Sojo, Jesus; Eguizabal, Cristina; Urbano, Fernando; Vesga, Miguel Angel; Pozenel, Primoz; van Kraaij, Marian; Hansen, Morten Bagge; Slot, Ed; Ullum, Henrik.
In: VOX SANG, Vol. 116, No. 3, vox.13014, 23.03.2021, p. 313-323.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Putting the spotlight on donation-related risks and donor safety - are we succeeding in protecting donors?
AU - Mikkelsen, Christina
AU - Mori, Gaia
AU - van Walraven, Suzanna M
AU - Castrén, Johanna
AU - Zahra, Sharon
AU - MacLennan, Sheila
AU - Seidel, Kirsten
AU - Fontana, Stefano
AU - Veropalumbo, Eva
AU - Cannata, Livia
AU - Pupella, Simonetta
AU - Kvist, Maria
AU - Happel, Marjan
AU - Korkalainen, Piia
AU - Wulff, Birgit
AU - Fernandez-Sojo, Jesus
AU - Eguizabal, Cristina
AU - Urbano, Fernando
AU - Vesga, Miguel Angel
AU - Pozenel, Primoz
AU - van Kraaij, Marian
AU - Hansen, Morten Bagge
AU - Slot, Ed
AU - Ullum, Henrik
N1 - © 2020 International Society of Blood Transfusion.
PY - 2021/3/23
Y1 - 2021/3/23
N2 - BACKGROUND AND OBJECTIVE: The European consortium project TRANSPOSE (TRANSfusion and transplantation: PrOtection and SElection of donors) aimed to assess and evaluate the risks to donors of Substances of Human Origin (SoHO), and to identify gaps between current donor vigilance systems and perceived risks.MATERIALS AND METHODS: National and local data from participating organizations on serious and non-serious adverse reactions in donors were collected from 2014 to 2017. Following this, a survey was performed among participants to identify risks not included in the data sets. Finally, participants rated the risks according to severity, level of evidence and prevalence.RESULTS: Significant discrepancies between anticipated donor risks and the collected data were found. Furthermore, many participants reported that national data on adverse reactions in donors of stem cells, gametes, embryos and tissues were not routinely collected and/or available.CONCLUSIONS: These findings indicate that there is a need to further develop and standardize donor vigilance in Europe and to include long-term risks to donors, which are currently underreported, ensuring donor health and securing the future supply of SoHO.
AB - BACKGROUND AND OBJECTIVE: The European consortium project TRANSPOSE (TRANSfusion and transplantation: PrOtection and SElection of donors) aimed to assess and evaluate the risks to donors of Substances of Human Origin (SoHO), and to identify gaps between current donor vigilance systems and perceived risks.MATERIALS AND METHODS: National and local data from participating organizations on serious and non-serious adverse reactions in donors were collected from 2014 to 2017. Following this, a survey was performed among participants to identify risks not included in the data sets. Finally, participants rated the risks according to severity, level of evidence and prevalence.RESULTS: Significant discrepancies between anticipated donor risks and the collected data were found. Furthermore, many participants reported that national data on adverse reactions in donors of stem cells, gametes, embryos and tissues were not routinely collected and/or available.CONCLUSIONS: These findings indicate that there is a need to further develop and standardize donor vigilance in Europe and to include long-term risks to donors, which are currently underreported, ensuring donor health and securing the future supply of SoHO.
U2 - 10.1111/vox.13014
DO - 10.1111/vox.13014
M3 - SCORING: Journal article
C2 - 33103801
VL - 116
SP - 313
EP - 323
JO - VOX SANG
JF - VOX SANG
SN - 0042-9007
IS - 3
M1 - vox.13014
ER -