PSMA Expression in Tumor Neovasculature Endothelial Cells of Follicular Thyroid Adenoma as Identified by Molecular Imaging Using 68Ga-PSMA Ligand PET/CT

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PSMA Expression in Tumor Neovasculature Endothelial Cells of Follicular Thyroid Adenoma as Identified by Molecular Imaging Using 68Ga-PSMA Ligand PET/CT. / Derlin, Thorsten; Kreipe, Hans-Heinrich; Schumacher, Udo; Soudah, Bisharah.

In: CLIN NUCL MED, Vol. 42, No. 3, 2017, p. e173-e174.

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@article{40c86fe7e66543038f237e9b14a0e49d,
title = "PSMA Expression in Tumor Neovasculature Endothelial Cells of Follicular Thyroid Adenoma as Identified by Molecular Imaging Using 68Ga-PSMA Ligand PET/CT",
abstract = "The prostate-specific membrane antigen (PSMA) is expressed by both prostate cancer and other neoplasms. We report the case of a 65-year-old man with castration-resistant metastatic prostate cancer who underwent Ga-PSMA ligand PET/CT for restaging of disease. Ga-PSMA ligand accumulation was noted in a thyroid lesion, suspicious for thyroid malignancy on complementary ultrasound. Subsequent resection and histopathological analysis showed follicular thyroid adenoma with PSMA expression in tumor neovasculature endothelial cells, but not in thyroid epithelial cells. It is important to be aware that both malignant and benign thyroid neoplasms may show PSMA expression to avoid misinterpretation.",
author = "Thorsten Derlin and Hans-Heinrich Kreipe and Udo Schumacher and Bisharah Soudah",
note = "Editorial Material",
year = "2017",
doi = "10.1097/RLU.0000000000001487",
language = "English",
volume = "42",
pages = "e173--e174",
journal = "CLIN NUCL MED",
issn = "0363-9762",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

RIS

TY - JOUR

T1 - PSMA Expression in Tumor Neovasculature Endothelial Cells of Follicular Thyroid Adenoma as Identified by Molecular Imaging Using 68Ga-PSMA Ligand PET/CT

AU - Derlin, Thorsten

AU - Kreipe, Hans-Heinrich

AU - Schumacher, Udo

AU - Soudah, Bisharah

N1 - Editorial Material

PY - 2017

Y1 - 2017

N2 - The prostate-specific membrane antigen (PSMA) is expressed by both prostate cancer and other neoplasms. We report the case of a 65-year-old man with castration-resistant metastatic prostate cancer who underwent Ga-PSMA ligand PET/CT for restaging of disease. Ga-PSMA ligand accumulation was noted in a thyroid lesion, suspicious for thyroid malignancy on complementary ultrasound. Subsequent resection and histopathological analysis showed follicular thyroid adenoma with PSMA expression in tumor neovasculature endothelial cells, but not in thyroid epithelial cells. It is important to be aware that both malignant and benign thyroid neoplasms may show PSMA expression to avoid misinterpretation.

AB - The prostate-specific membrane antigen (PSMA) is expressed by both prostate cancer and other neoplasms. We report the case of a 65-year-old man with castration-resistant metastatic prostate cancer who underwent Ga-PSMA ligand PET/CT for restaging of disease. Ga-PSMA ligand accumulation was noted in a thyroid lesion, suspicious for thyroid malignancy on complementary ultrasound. Subsequent resection and histopathological analysis showed follicular thyroid adenoma with PSMA expression in tumor neovasculature endothelial cells, but not in thyroid epithelial cells. It is important to be aware that both malignant and benign thyroid neoplasms may show PSMA expression to avoid misinterpretation.

U2 - 10.1097/RLU.0000000000001487

DO - 10.1097/RLU.0000000000001487

M3 - Other (editorial matter etc.)

C2 - 27997422

VL - 42

SP - e173-e174

JO - CLIN NUCL MED

JF - CLIN NUCL MED

SN - 0363-9762

IS - 3

ER -