Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer.
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Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer. / Müller, Volkmar; Riethdorf, Sabine; Rack, Brigitte; Janni, Wolfgang; Fasching, Peter A; Solomayer, Erich; Aktas, Bahriye; Kasimir-Bauer, Sabine; Zeitz, Julia; Pantel, Klaus; Fehm, Tanja; Group, DETECT Study.
In: BREAST CANCER RES, Vol. 13, No. 4, 4, 2011, p. 71.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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T1 - Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer.
AU - Müller, Volkmar
AU - Riethdorf, Sabine
AU - Rack, Brigitte
AU - Janni, Wolfgang
AU - Fasching, Peter A
AU - Solomayer, Erich
AU - Aktas, Bahriye
AU - Kasimir-Bauer, Sabine
AU - Zeitz, Julia
AU - Pantel, Klaus
AU - Fehm, Tanja
AU - Group, DETECT Study
PY - 2011
Y1 - 2011
N2 - Circulating tumor cells (CTCs) reflect aggressive tumor behavior by hematogenous tumor cell dissemination. The tissue inhibitor of metalloproteinase 1 (TIMP-1) plays a role in tissue invasion and is also involved in angiogenesis, abrogation of apoptosis and in chemoresistance. Carbonic anhydrase IX (CAIX) is a metalloenzyme involved in cell adhesion, growth and survival of tumor cells. The aim of the study was to investigate whether serum concentrations of TIMP-1 and CAIX are associated with the detection of CTC in metastatic breast cancer.
AB - Circulating tumor cells (CTCs) reflect aggressive tumor behavior by hematogenous tumor cell dissemination. The tissue inhibitor of metalloproteinase 1 (TIMP-1) plays a role in tissue invasion and is also involved in angiogenesis, abrogation of apoptosis and in chemoresistance. Carbonic anhydrase IX (CAIX) is a metalloenzyme involved in cell adhesion, growth and survival of tumor cells. The aim of the study was to investigate whether serum concentrations of TIMP-1 and CAIX are associated with the detection of CTC in metastatic breast cancer.
U2 - 10.1186/bcr2916
DO - 10.1186/bcr2916
M3 - SCORING: Journal article
VL - 13
SP - 71
JO - BREAST CANCER RES
JF - BREAST CANCER RES
SN - 1465-5411
IS - 4
M1 - 4
ER -