Prolactin but not ACTH increases during sodium lactate-induced panic attacks.
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Prolactin but not ACTH increases during sodium lactate-induced panic attacks. / Otte, Christian; Kellner, Michael; Arlt, Josef; Jahn, Holger; Holsboer, Florian; Wiedemann, Klaus.
In: PSYCHIAT RES, Vol. 109, No. 2, 2, 2002, p. 201-205.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Prolactin but not ACTH increases during sodium lactate-induced panic attacks.
AU - Otte, Christian
AU - Kellner, Michael
AU - Arlt, Josef
AU - Jahn, Holger
AU - Holsboer, Florian
AU - Wiedemann, Klaus
PY - 2002
Y1 - 2002
N2 - Paradoxically, the pituitary-adrenal axis is not activated during sodium lactate-induced panic. We measured the response of another stress-sensitive hormone, prolactin, to standard lactate and placebo infusion in a double-blind randomised design in eight patients with panic disorder and eight matched normal controls. Prolactin release was significantly elevated (P <0.05) in panickers compared with non-panickers, whereas ACTH secretion was not activated at all. This differential stress response needs further investigation.
AB - Paradoxically, the pituitary-adrenal axis is not activated during sodium lactate-induced panic. We measured the response of another stress-sensitive hormone, prolactin, to standard lactate and placebo infusion in a double-blind randomised design in eight patients with panic disorder and eight matched normal controls. Prolactin release was significantly elevated (P <0.05) in panickers compared with non-panickers, whereas ACTH secretion was not activated at all. This differential stress response needs further investigation.
M3 - SCORING: Zeitschriftenaufsatz
VL - 109
SP - 201
EP - 205
JO - PSYCHIAT RES
JF - PSYCHIAT RES
SN - 0165-1781
IS - 2
M1 - 2
ER -