Research ExplorerPublicationsProgrediente Luftnot und Schwäche bei einer 61-jährigen Pati...

Progrediente Luftnot und Schwäche bei einer 61-jährigen Patientin

Standard

Progrediente Luftnot und Schwäche bei einer 61-jährigen Patientin. / Mahmud, M; Schnoor, U; Steinmetz, O M.

In: INTERNIST, Vol. 60, No. 2, 02.2019, p. 186-192.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Mahmud, M, Schnoor, U & Steinmetz, OM 2019, 'Progrediente Luftnot und Schwäche bei einer 61-jährigen Patientin', INTERNIST, vol. 60, no. 2, pp. 186-192. https://doi.org/10.1007/s00108-018-0490-6

APA

Mahmud, M., Schnoor, U., & Steinmetz, O. M. (2019). Progrediente Luftnot und Schwäche bei einer 61-jährigen Patientin. INTERNIST, 60(2), 186-192. https://doi.org/10.1007/s00108-018-0490-6

Vancouver

Mahmud M, Schnoor U, Steinmetz OM. Progrediente Luftnot und Schwäche bei einer 61-jährigen Patientin. INTERNIST. 2019 Feb;60(2):186-192. https://doi.org/10.1007/s00108-018-0490-6

Bibtex

@article{d8e33e4ce29a4c62bc9b45ef98ead6ba,
title = "Progrediente Luftnot und Schw{\"a}che bei einer 61-j{\"a}hrigen Patientin",
abstract = "A 61-year-old woman was admitted with a suspected diagnosis of atypical pneumonia. Extended diagnostic measures revealed interstitial lung disease (ILD), polyserositis, polyarthritis and myopathy. With detection of an antibody against PL-7 (anti-threonyl-transfer-RNA synthetase) the diagnosis of anti-synthetase syndrome (ASS) was established. ASS are rare inflammatory myopathies which frequently present as multisystemic diseases with severe organ involvement. An immunosuppressive regimen with steroids and cyclophosphamide led to successful induction of disease remission. Maintenance therapy will be conducted with azathioprine. ASS should always be considered in the differential diagnosis of myopathies and ILDs.",
keywords = "Amino Acyl-tRNA Synthetases/immunology, Antibodies, Antinuclear, Autoantibodies/immunology, Azathioprine/therapeutic use, Combined Modality Therapy, Cyclophosphamide/therapeutic use, Female, Humans, Immunosuppressive Agents/therapeutic use, Lung/pathology, Lung Diseases, Interstitial/diagnosis, Methylprednisolone/therapeutic use, Middle Aged, Muscle, Skeletal/physiopathology, Myositis/diagnosis, Respiratory Insufficiency/diagnosis, Treatment Outcome",
author = "M Mahmud and U Schnoor and Steinmetz, {O M}",
year = "2019",
month = feb,
doi = "10.1007/s00108-018-0490-6",
language = "Deutsch",
volume = "60",
pages = "186--192",
journal = "INTERNIST",
issn = "0020-9554",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Progrediente Luftnot und Schwäche bei einer 61-jährigen Patientin

AU - Mahmud, M

AU - Schnoor, U

AU - Steinmetz, O M

PY - 2019/2

Y1 - 2019/2

N2 - A 61-year-old woman was admitted with a suspected diagnosis of atypical pneumonia. Extended diagnostic measures revealed interstitial lung disease (ILD), polyserositis, polyarthritis and myopathy. With detection of an antibody against PL-7 (anti-threonyl-transfer-RNA synthetase) the diagnosis of anti-synthetase syndrome (ASS) was established. ASS are rare inflammatory myopathies which frequently present as multisystemic diseases with severe organ involvement. An immunosuppressive regimen with steroids and cyclophosphamide led to successful induction of disease remission. Maintenance therapy will be conducted with azathioprine. ASS should always be considered in the differential diagnosis of myopathies and ILDs.

AB - A 61-year-old woman was admitted with a suspected diagnosis of atypical pneumonia. Extended diagnostic measures revealed interstitial lung disease (ILD), polyserositis, polyarthritis and myopathy. With detection of an antibody against PL-7 (anti-threonyl-transfer-RNA synthetase) the diagnosis of anti-synthetase syndrome (ASS) was established. ASS are rare inflammatory myopathies which frequently present as multisystemic diseases with severe organ involvement. An immunosuppressive regimen with steroids and cyclophosphamide led to successful induction of disease remission. Maintenance therapy will be conducted with azathioprine. ASS should always be considered in the differential diagnosis of myopathies and ILDs.

KW - Amino Acyl-tRNA Synthetases/immunology

KW - Antibodies, Antinuclear

KW - Autoantibodies/immunology

KW - Azathioprine/therapeutic use

KW - Combined Modality Therapy

KW - Cyclophosphamide/therapeutic use

KW - Female

KW - Humans

KW - Immunosuppressive Agents/therapeutic use

KW - Lung/pathology

KW - Lung Diseases, Interstitial/diagnosis

KW - Methylprednisolone/therapeutic use

KW - Middle Aged

KW - Muscle, Skeletal/physiopathology

KW - Myositis/diagnosis

KW - Respiratory Insufficiency/diagnosis

KW - Treatment Outcome

U2 - 10.1007/s00108-018-0490-6

DO - 10.1007/s00108-018-0490-6

M3 - SCORING: Zeitschriftenaufsatz

C2 - 30218200

VL - 60

SP - 186

EP - 192

JO - INTERNIST

JF - INTERNIST

SN - 0020-9554

IS - 2

ER -