Prognostic significance of serum S100B detection compared with routine blood parameters in advanced metastatic melanoma patients.
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Prognostic significance of serum S100B detection compared with routine blood parameters in advanced metastatic melanoma patients. / Hauschild, A; Michaelsen, J; Brenner, Winfried; Rudolph, P; Gläser, R; Henze, E; Christophers, E.
In: MELANOMA RES, Vol. 9, No. 2, 2, 1999, p. 155-161.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Prognostic significance of serum S100B detection compared with routine blood parameters in advanced metastatic melanoma patients.
AU - Hauschild, A
AU - Michaelsen, J
AU - Brenner, Winfried
AU - Rudolph, P
AU - Gläser, R
AU - Henze, E
AU - Christophers, E
PY - 1999
Y1 - 1999
N2 - Recent reports on the use of a quantitative measurement of S100B protein for the detection of metastatic melanoma have yielded promising results. In this study we evaluated 489 serum samples from 64 patients suffering from advanced melanoma (UICC/AJCC stage IV) to compare the sensitivity of a S100B immunoradiometric assay (IRMA) with that of conventional blood parameters as well as other known clinical prognostic factors. In a univariate statistical analysis, gender, bone metastasis, and lactate dehydrogenase and S100B levels in serum samples were found to be significant prognostic markers (P
AB - Recent reports on the use of a quantitative measurement of S100B protein for the detection of metastatic melanoma have yielded promising results. In this study we evaluated 489 serum samples from 64 patients suffering from advanced melanoma (UICC/AJCC stage IV) to compare the sensitivity of a S100B immunoradiometric assay (IRMA) with that of conventional blood parameters as well as other known clinical prognostic factors. In a univariate statistical analysis, gender, bone metastasis, and lactate dehydrogenase and S100B levels in serum samples were found to be significant prognostic markers (P
M3 - SCORING: Zeitschriftenaufsatz
VL - 9
SP - 155
EP - 161
JO - MELANOMA RES
JF - MELANOMA RES
SN - 0960-8931
IS - 2
M1 - 2
ER -