Prognostic information for people with MS: Impossible or inevitable
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Prognostic information for people with MS: Impossible or inevitable. / Heesen, Christoph; Scalfari, Antonio; Galea, Ian.
In: MULT SCLER J, Vol. 26, No. 7, 06.2020, p. 771-773.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
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TY - JOUR
T1 - Prognostic information for people with MS: Impossible or inevitable
AU - Heesen, Christoph
AU - Scalfari, Antonio
AU - Galea, Ian
PY - 2020/6
Y1 - 2020/6
N2 - Delivering prognostic information is a challenging issue in medicine and has been largely neglected in the past. A major reason has been a suspected nocebo effect of pessimistic estimates, although this is largely unproven. Among people with multiple sclerosis (MS), there is a strong unmet need to receive long-term prognostic information. This viewpoint discusses reasons for this blind spot in physicians' attitude, foremost among which is the uncertainty of prognostic estimates. Possible strategies to move forward include tools to identify matching patients from large well-defined databases, to deliver an evidence-based individualized estimate of long-term prognosis, and its confidence interval, in a clinical setting.
AB - Delivering prognostic information is a challenging issue in medicine and has been largely neglected in the past. A major reason has been a suspected nocebo effect of pessimistic estimates, although this is largely unproven. Among people with multiple sclerosis (MS), there is a strong unmet need to receive long-term prognostic information. This viewpoint discusses reasons for this blind spot in physicians' attitude, foremost among which is the uncertainty of prognostic estimates. Possible strategies to move forward include tools to identify matching patients from large well-defined databases, to deliver an evidence-based individualized estimate of long-term prognosis, and its confidence interval, in a clinical setting.
KW - Journal Article
U2 - 10.1177/1352458518807101
DO - 10.1177/1352458518807101
M3 - Other (editorial matter etc.)
C2 - 30325713
VL - 26
SP - 771
EP - 773
JO - MULT SCLER J
JF - MULT SCLER J
SN - 1352-4585
IS - 7
ER -