Prognostic impact of left bundle-branch block in the early stable phase after acute myocardial infarction.

  • Rüdiger Dissmann
  • Wolfram Kamke
  • Rona Reibis
  • Joachim Herbstleb
  • Karl Wegscheider
  • Heinz Völler

Abstract

BACKGROUND: Diagnostic marker parameters are needed to enable timely identification of high risk patients after acute myocardial infarction (MI). We assessed risk factors for death and sudden death in stable revascularized patients undergoing guideline-based therapy during an in-patient rehabilitation program more than 3 weeks after acute myocardial infarction. METHODS: During an in-patient rehabilitation program, 939 patients with a recent myocardial infarction were prospectively included. Besides demographic and clinical data, ejection fraction (EF), Holter ECG, standard 12-lead electrocardiogram (ECG) and baseline laboratory values were determined. Patients were followed up for 18 months. RESULTS: Among multiple variables, left bundle-branch block (LBBB) was the most significant parameter affecting the outcome (combination endpoint of death, resuscitation or ventricular tachycardia (VT)), hazard ratio 7.74 (3.2-18.7, P

Bibliographical data

Original languageGerman
Article number3
ISSN0167-5273
Publication statusPublished - 2008
pubmed 18191251