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Pro- and anti-inflammatory cytokines in the CSF of patients with Creutzfeldt-Jakob disease.

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Pro- and anti-inflammatory cytokines in the CSF of patients with Creutzfeldt-Jakob disease. / Stoeck, Katharina; Bodemer, Monika; Zerr, Inga.

In: J NEUROIMMUNOL, Vol. 172, No. 1-2, 1-2, 2006, p. 175-181.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Stoeck, K, Bodemer, M & Zerr, I 2006, 'Pro- and anti-inflammatory cytokines in the CSF of patients with Creutzfeldt-Jakob disease.', J NEUROIMMUNOL, vol. 172, no. 1-2, 1-2, pp. 175-181. <http://www.ncbi.nlm.nih.gov/pubmed/16330103?dopt=Citation>

APA

Stoeck, K., Bodemer, M., & Zerr, I. (2006). Pro- and anti-inflammatory cytokines in the CSF of patients with Creutzfeldt-Jakob disease. J NEUROIMMUNOL, 172(1-2), 175-181. [1-2]. http://www.ncbi.nlm.nih.gov/pubmed/16330103?dopt=Citation

Vancouver

Stoeck K, Bodemer M, Zerr I. Pro- and anti-inflammatory cytokines in the CSF of patients with Creutzfeldt-Jakob disease. J NEUROIMMUNOL. 2006;172(1-2):175-181. 1-2.

Bibtex

@article{b8d14e41eb674843adfc8b7a572746dd,
title = "Pro- and anti-inflammatory cytokines in the CSF of patients with Creutzfeldt-Jakob disease.",
abstract = "We investigated cerebrospinal fluid (CSF) samples from patients with Creutzfeldt-Jakob disease (CJD) and other neurological diseases. Concentrations of pro- and anti-inflammatory cytokines IL-1beta, IL-6, IL-8, IL-12, TNF-alpha and TGF-beta 2 were determined in CSF using ELISA. Significant changes were found for IL-8 and TGF-beta 2. IL-8 levels were elevated in the CSF of CJD patients. Of interest, the increase was significant to other dementia and to controls. In contrast, TGF-beta 2 was significantly decreased in CSF of CJD compared to all groups. IL-1beta, IL-12 and TNF-alpha could not be detected in CSF or in case of IL-6 in only low concentrations without significant difference.",
author = "Katharina Stoeck and Monika Bodemer and Inga Zerr",
year = "2006",
language = "Deutsch",
volume = "172",
pages = "175--181",
journal = "J NEUROIMMUNOL",
issn = "0165-5728",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - Pro- and anti-inflammatory cytokines in the CSF of patients with Creutzfeldt-Jakob disease.

AU - Stoeck, Katharina

AU - Bodemer, Monika

AU - Zerr, Inga

PY - 2006

Y1 - 2006

N2 - We investigated cerebrospinal fluid (CSF) samples from patients with Creutzfeldt-Jakob disease (CJD) and other neurological diseases. Concentrations of pro- and anti-inflammatory cytokines IL-1beta, IL-6, IL-8, IL-12, TNF-alpha and TGF-beta 2 were determined in CSF using ELISA. Significant changes were found for IL-8 and TGF-beta 2. IL-8 levels were elevated in the CSF of CJD patients. Of interest, the increase was significant to other dementia and to controls. In contrast, TGF-beta 2 was significantly decreased in CSF of CJD compared to all groups. IL-1beta, IL-12 and TNF-alpha could not be detected in CSF or in case of IL-6 in only low concentrations without significant difference.

AB - We investigated cerebrospinal fluid (CSF) samples from patients with Creutzfeldt-Jakob disease (CJD) and other neurological diseases. Concentrations of pro- and anti-inflammatory cytokines IL-1beta, IL-6, IL-8, IL-12, TNF-alpha and TGF-beta 2 were determined in CSF using ELISA. Significant changes were found for IL-8 and TGF-beta 2. IL-8 levels were elevated in the CSF of CJD patients. Of interest, the increase was significant to other dementia and to controls. In contrast, TGF-beta 2 was significantly decreased in CSF of CJD compared to all groups. IL-1beta, IL-12 and TNF-alpha could not be detected in CSF or in case of IL-6 in only low concentrations without significant difference.

M3 - SCORING: Zeitschriftenaufsatz

VL - 172

SP - 175

EP - 181

JO - J NEUROIMMUNOL

JF - J NEUROIMMUNOL

SN - 0165-5728

IS - 1-2

M1 - 1-2

ER -