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Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis

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Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis. / Mariscalco, Giovanni; Rosato, Stefano; Serraino, Giuseppe F; Maselli, Daniele; Dalén, Magnus; Airaksinen, Juhani K E; Reichart, Daniel; Zanobini, Marco; Onorati, Francesco; De Feo, Marisa; Gherli, Riccardo; Santarpino, Giuseppe; Rubino, Antonino S; Gatti, Giuseppe; Nicolini, Francesco; Santini, Francesco; Perrotti, Andrea; Bruno, Vito D; Ruggieri, Vito G; Biancari, Fausto.

In: CIRC-CARDIOVASC INTE, Vol. 11, No. 2, 02.2018, p. e005650.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Mariscalco, G, Rosato, S, Serraino, GF, Maselli, D, Dalén, M, Airaksinen, JKE, Reichart, D, Zanobini, M, Onorati, F, De Feo, M, Gherli, R, Santarpino, G, Rubino, AS, Gatti, G, Nicolini, F, Santini, F, Perrotti, A, Bruno, VD, Ruggieri, VG & Biancari, F 2018, 'Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis', CIRC-CARDIOVASC INTE, vol. 11, no. 2, pp. e005650. https://doi.org/10.1161/CIRCINTERVENTIONS.117.005650

APA

Mariscalco, G., Rosato, S., Serraino, G. F., Maselli, D., Dalén, M., Airaksinen, J. K. E., Reichart, D., Zanobini, M., Onorati, F., De Feo, M., Gherli, R., Santarpino, G., Rubino, A. S., Gatti, G., Nicolini, F., Santini, F., Perrotti, A., Bruno, V. D., Ruggieri, V. G., & Biancari, F. (2018). Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis. CIRC-CARDIOVASC INTE, 11(2), e005650. https://doi.org/10.1161/CIRCINTERVENTIONS.117.005650

Vancouver

Mariscalco G, Rosato S, Serraino GF, Maselli D, Dalén M, Airaksinen JKE et al. Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis. CIRC-CARDIOVASC INTE. 2018 Feb;11(2):e005650. https://doi.org/10.1161/CIRCINTERVENTIONS.117.005650

Bibtex

@article{1c7f5b6bb50642a586edd62dd310e542,
title = "Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis",
abstract = "BACKGROUND: The clinical impact of prior percutaneous coronary intervention (PCI) in patients requiring coronary artery bypass grafting (CABG) remains unsettled. We sought to determine whether prior PCI is associated with adverse outcome after CABG.METHODS AND RESULTS: Data from the prospective E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) conducted between January 2015 and March 2016 at 16 European centres were analyzed using propensity weighted methodology to adjust for confounding. A parallel systematic review/meta-analysis (MEDLINE, Embase, SCOPUS, and Cochrane Library) through September 2017 was accomplished. Of a total of 3641 adult patients included in the E-CABG study, 685 (19%) patients had a history of PCI. At multivariable level, prior PCI was not associated with an increased hospital mortality in both unweighted and weighted patient groups (odds ratio, 0.73; 95% confidence interval, 0.29-1.38; P=0.33 and odds ratio, 0.90; 95% confidence interval, 0.39-2.08; P=0.81, respectively). Subgroup analyses confirmed that prior PCI had no impact on hospital mortality and morbidity, including reexploration for bleeding, blood transfusion, hospital resource use, and neurological, renal, and cardiac complications. The systematic review provided a total of 71 366 individuals and showed a trend toward higher in-hospital/30-day mortality (adjusted odds ratio, 1.30; 95% confidence interval, 0.99-1.70; I2=43.1%) in patients with prior PCI.CONCLUSIONS: Our prospective multicenter study showed that prior PCI was not associated with an increased risk of mortality or other adverse outcomes in patients undergoing CABG. In light of a trend toward increased mortality observed in the meta-analysis, further studies are needed to ascertain the prognostic impact of prior PCI in the outcome after CABG.CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02319083.",
keywords = "Aged, Coronary Artery Bypass/adverse effects, Coronary Artery Disease/diagnostic imaging, Europe, Female, Hospital Mortality, Humans, Male, Middle Aged, Percutaneous Coronary Intervention/adverse effects, Postoperative Complications/mortality, Prospective Studies, Registries, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome",
author = "Giovanni Mariscalco and Stefano Rosato and Serraino, {Giuseppe F} and Daniele Maselli and Magnus Dal{\'e}n and Airaksinen, {Juhani K E} and Daniel Reichart and Marco Zanobini and Francesco Onorati and {De Feo}, Marisa and Riccardo Gherli and Giuseppe Santarpino and Rubino, {Antonino S} and Giuseppe Gatti and Francesco Nicolini and Francesco Santini and Andrea Perrotti and Bruno, {Vito D} and Ruggieri, {Vito G} and Fausto Biancari",
note = "{\textcopyright} 2018 American Heart Association, Inc.",
year = "2018",
month = feb,
doi = "10.1161/CIRCINTERVENTIONS.117.005650",
language = "English",
volume = "11",
pages = "e005650",
journal = "CIRC-CARDIOVASC INTE",
issn = "1941-7640",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

RIS

TY - JOUR

T1 - Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis

AU - Mariscalco, Giovanni

AU - Rosato, Stefano

AU - Serraino, Giuseppe F

AU - Maselli, Daniele

AU - Dalén, Magnus

AU - Airaksinen, Juhani K E

AU - Reichart, Daniel

AU - Zanobini, Marco

AU - Onorati, Francesco

AU - De Feo, Marisa

AU - Gherli, Riccardo

AU - Santarpino, Giuseppe

AU - Rubino, Antonino S

AU - Gatti, Giuseppe

AU - Nicolini, Francesco

AU - Santini, Francesco

AU - Perrotti, Andrea

AU - Bruno, Vito D

AU - Ruggieri, Vito G

AU - Biancari, Fausto

N1 - © 2018 American Heart Association, Inc.

PY - 2018/2

Y1 - 2018/2

N2 - BACKGROUND: The clinical impact of prior percutaneous coronary intervention (PCI) in patients requiring coronary artery bypass grafting (CABG) remains unsettled. We sought to determine whether prior PCI is associated with adverse outcome after CABG.METHODS AND RESULTS: Data from the prospective E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) conducted between January 2015 and March 2016 at 16 European centres were analyzed using propensity weighted methodology to adjust for confounding. A parallel systematic review/meta-analysis (MEDLINE, Embase, SCOPUS, and Cochrane Library) through September 2017 was accomplished. Of a total of 3641 adult patients included in the E-CABG study, 685 (19%) patients had a history of PCI. At multivariable level, prior PCI was not associated with an increased hospital mortality in both unweighted and weighted patient groups (odds ratio, 0.73; 95% confidence interval, 0.29-1.38; P=0.33 and odds ratio, 0.90; 95% confidence interval, 0.39-2.08; P=0.81, respectively). Subgroup analyses confirmed that prior PCI had no impact on hospital mortality and morbidity, including reexploration for bleeding, blood transfusion, hospital resource use, and neurological, renal, and cardiac complications. The systematic review provided a total of 71 366 individuals and showed a trend toward higher in-hospital/30-day mortality (adjusted odds ratio, 1.30; 95% confidence interval, 0.99-1.70; I2=43.1%) in patients with prior PCI.CONCLUSIONS: Our prospective multicenter study showed that prior PCI was not associated with an increased risk of mortality or other adverse outcomes in patients undergoing CABG. In light of a trend toward increased mortality observed in the meta-analysis, further studies are needed to ascertain the prognostic impact of prior PCI in the outcome after CABG.CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02319083.

AB - BACKGROUND: The clinical impact of prior percutaneous coronary intervention (PCI) in patients requiring coronary artery bypass grafting (CABG) remains unsettled. We sought to determine whether prior PCI is associated with adverse outcome after CABG.METHODS AND RESULTS: Data from the prospective E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) conducted between January 2015 and March 2016 at 16 European centres were analyzed using propensity weighted methodology to adjust for confounding. A parallel systematic review/meta-analysis (MEDLINE, Embase, SCOPUS, and Cochrane Library) through September 2017 was accomplished. Of a total of 3641 adult patients included in the E-CABG study, 685 (19%) patients had a history of PCI. At multivariable level, prior PCI was not associated with an increased hospital mortality in both unweighted and weighted patient groups (odds ratio, 0.73; 95% confidence interval, 0.29-1.38; P=0.33 and odds ratio, 0.90; 95% confidence interval, 0.39-2.08; P=0.81, respectively). Subgroup analyses confirmed that prior PCI had no impact on hospital mortality and morbidity, including reexploration for bleeding, blood transfusion, hospital resource use, and neurological, renal, and cardiac complications. The systematic review provided a total of 71 366 individuals and showed a trend toward higher in-hospital/30-day mortality (adjusted odds ratio, 1.30; 95% confidence interval, 0.99-1.70; I2=43.1%) in patients with prior PCI.CONCLUSIONS: Our prospective multicenter study showed that prior PCI was not associated with an increased risk of mortality or other adverse outcomes in patients undergoing CABG. In light of a trend toward increased mortality observed in the meta-analysis, further studies are needed to ascertain the prognostic impact of prior PCI in the outcome after CABG.CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02319083.

KW - Aged

KW - Coronary Artery Bypass/adverse effects

KW - Coronary Artery Disease/diagnostic imaging

KW - Europe

KW - Female

KW - Hospital Mortality

KW - Humans

KW - Male

KW - Middle Aged

KW - Percutaneous Coronary Intervention/adverse effects

KW - Postoperative Complications/mortality

KW - Prospective Studies

KW - Registries

KW - Risk Assessment

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1161/CIRCINTERVENTIONS.117.005650

DO - 10.1161/CIRCINTERVENTIONS.117.005650

M3 - SCORING: Journal article

C2 - 29440275

VL - 11

SP - e005650

JO - CIRC-CARDIOVASC INTE

JF - CIRC-CARDIOVASC INTE

SN - 1941-7640

IS - 2

ER -