Primary hypothyroidism resolves after switching from L-thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome

  • Sophie Stupperich
  • Jessica Kotliarevskaia
  • Reinhold Nies
  • Maria Paparoupa
  • Andreas Wittig
  • Frank Schuppert

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Abstract

A case of refractory primary hypothyroidism is presented. Despite laboratory-guided hormonal substitution, the patient remained hypothyroid. Multiple diagnostic tests ruled out all known causes of levothyroxine malabsorption. Interestingly, clinical and laboratory responding was promptly achieved, after switching the application format from solid tablets to liquid formula.

Bibliographical data

Original languageEnglish
Article numbere6223
ISSN2050-0904
DOIs
Publication statusPublished - 08.2022

Comment Deanary

© 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

PubMed 35990384