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Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience

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Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience. / Westermann, Dirk; Ludwig, Sebastian; Kalbacher, Daniel; Spink, Clemens; Linder, Matthias; Bhadra, Oliver D; Nikorowitsch, Julius; Waldschmidt, Lara; Demal, Till; Voigtländer, Lisa; Schaefer, Andreas; Seiffert, Moritz; Pecha, Simon; Schofer, Niklas; Greenbaum, Adam B; Reichenspurner, Hermann; Blankenberg, Stefan; Conradi, Lenard; Schirmer, Johannes.

In: CLIN RES CARDIOL, Vol. 110, No. 12, 12.2021, p. 1900-1911.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Westermann, D, Ludwig, S, Kalbacher, D, Spink, C, Linder, M, Bhadra, OD, Nikorowitsch, J, Waldschmidt, L, Demal, T, Voigtländer, L, Schaefer, A, Seiffert, M, Pecha, S, Schofer, N, Greenbaum, AB, Reichenspurner, H, Blankenberg, S, Conradi, L & Schirmer, J 2021, 'Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience', CLIN RES CARDIOL, vol. 110, no. 12, pp. 1900-1911. https://doi.org/10.1007/s00392-021-01881-4

APA

Westermann, D., Ludwig, S., Kalbacher, D., Spink, C., Linder, M., Bhadra, O. D., Nikorowitsch, J., Waldschmidt, L., Demal, T., Voigtländer, L., Schaefer, A., Seiffert, M., Pecha, S., Schofer, N., Greenbaum, A. B., Reichenspurner, H., Blankenberg, S., Conradi, L., & Schirmer, J. (2021). Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience. CLIN RES CARDIOL, 110(12), 1900-1911. https://doi.org/10.1007/s00392-021-01881-4

Vancouver

Westermann D, Ludwig S, Kalbacher D, Spink C, Linder M, Bhadra OD et al. Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience. CLIN RES CARDIOL. 2021 Dec;110(12):1900-1911. https://doi.org/10.1007/s00392-021-01881-4

Bibtex

@article{218c9ae2853e4908ac358f3cef1e4573,
title = "Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience",
abstract = "OBJECTIVES: This study aimed to assess the clinical outcome of the bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary obstruction (BASILICA) technique in a single-center patient cohort considered at high or prohibitive risk of transcatheter aortic valve implantation (TAVI)-induced coronary obstruction.METHODS: Between October 2019 and January 2021, a total of 15 consecutive patients (age 81.0 [78.1, 84.4] years; 53.3% female; EuroSCORE II 10.6 [6.3, 14.8] %) underwent BASILICA procedure prior to TAVI at our institution. Indications for TAVI were degeneration of stented (n = 12, 80.0%) or stentless (n = 1, 6.7%) bioprosthetic aortic valves, or calcific stenosis of native aortic valves (n = 2, 13.3%), respectively. Individual risk of TAVI-induced coronary obstruction was assessed by pre-procedural computed tomography analysis. Procedural and 30-day outcomes were documented in accordance with Valve Academic Research Consortium (VARC)-2 criteria.RESULTS: BASILICA was attempted for single left coronary cusp in 12 patients (80.0%), for single right coronary cusp in 2 patients (13.3%), and for both cusps in 1 patient (6.7%), respectively. The procedure was feasible in 13 patients (86.7%) resulting in effective prevention of coronary obstruction, whilst TAVI was performed without prior successful bioprosthetic leaflet laceration in two patients (13.3%). In one of these patients (6.7%), additional chimney stenting immediately after TAVI was performed. No all-cause deaths or strokes were documented after 30 days.CONCLUSION: The BASILICA technique appears to be a feasible, safe and effective concept to avoid iatrogenic coronary artery obstruction during TAVI in both native and bioprosthetic valves of patients at high or prohibitive risk. ClinicalTrials.gov Identifier: NCT04227002 (Hamburg AoRtic Valve cOhoRt).",
author = "Dirk Westermann and Sebastian Ludwig and Daniel Kalbacher and Clemens Spink and Matthias Linder and Bhadra, {Oliver D} and Julius Nikorowitsch and Lara Waldschmidt and Till Demal and Lisa Voigtl{\"a}nder and Andreas Schaefer and Moritz Seiffert and Simon Pecha and Niklas Schofer and Greenbaum, {Adam B} and Hermann Reichenspurner and Stefan Blankenberg and Lenard Conradi and Johannes Schirmer",
note = "{\textcopyright} 2021. The Author(s).",
year = "2021",
month = dec,
doi = "10.1007/s00392-021-01881-4",
language = "English",
volume = "110",
pages = "1900--1911",
journal = "CLIN RES CARDIOL",
issn = "1861-0684",
publisher = "D. Steinkopff-Verlag",
number = "12",

}

RIS

TY - JOUR

T1 - Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience

AU - Westermann, Dirk

AU - Ludwig, Sebastian

AU - Kalbacher, Daniel

AU - Spink, Clemens

AU - Linder, Matthias

AU - Bhadra, Oliver D

AU - Nikorowitsch, Julius

AU - Waldschmidt, Lara

AU - Demal, Till

AU - Voigtländer, Lisa

AU - Schaefer, Andreas

AU - Seiffert, Moritz

AU - Pecha, Simon

AU - Schofer, Niklas

AU - Greenbaum, Adam B

AU - Reichenspurner, Hermann

AU - Blankenberg, Stefan

AU - Conradi, Lenard

AU - Schirmer, Johannes

N1 - © 2021. The Author(s).

PY - 2021/12

Y1 - 2021/12

N2 - OBJECTIVES: This study aimed to assess the clinical outcome of the bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary obstruction (BASILICA) technique in a single-center patient cohort considered at high or prohibitive risk of transcatheter aortic valve implantation (TAVI)-induced coronary obstruction.METHODS: Between October 2019 and January 2021, a total of 15 consecutive patients (age 81.0 [78.1, 84.4] years; 53.3% female; EuroSCORE II 10.6 [6.3, 14.8] %) underwent BASILICA procedure prior to TAVI at our institution. Indications for TAVI were degeneration of stented (n = 12, 80.0%) or stentless (n = 1, 6.7%) bioprosthetic aortic valves, or calcific stenosis of native aortic valves (n = 2, 13.3%), respectively. Individual risk of TAVI-induced coronary obstruction was assessed by pre-procedural computed tomography analysis. Procedural and 30-day outcomes were documented in accordance with Valve Academic Research Consortium (VARC)-2 criteria.RESULTS: BASILICA was attempted for single left coronary cusp in 12 patients (80.0%), for single right coronary cusp in 2 patients (13.3%), and for both cusps in 1 patient (6.7%), respectively. The procedure was feasible in 13 patients (86.7%) resulting in effective prevention of coronary obstruction, whilst TAVI was performed without prior successful bioprosthetic leaflet laceration in two patients (13.3%). In one of these patients (6.7%), additional chimney stenting immediately after TAVI was performed. No all-cause deaths or strokes were documented after 30 days.CONCLUSION: The BASILICA technique appears to be a feasible, safe and effective concept to avoid iatrogenic coronary artery obstruction during TAVI in both native and bioprosthetic valves of patients at high or prohibitive risk. ClinicalTrials.gov Identifier: NCT04227002 (Hamburg AoRtic Valve cOhoRt).

AB - OBJECTIVES: This study aimed to assess the clinical outcome of the bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary obstruction (BASILICA) technique in a single-center patient cohort considered at high or prohibitive risk of transcatheter aortic valve implantation (TAVI)-induced coronary obstruction.METHODS: Between October 2019 and January 2021, a total of 15 consecutive patients (age 81.0 [78.1, 84.4] years; 53.3% female; EuroSCORE II 10.6 [6.3, 14.8] %) underwent BASILICA procedure prior to TAVI at our institution. Indications for TAVI were degeneration of stented (n = 12, 80.0%) or stentless (n = 1, 6.7%) bioprosthetic aortic valves, or calcific stenosis of native aortic valves (n = 2, 13.3%), respectively. Individual risk of TAVI-induced coronary obstruction was assessed by pre-procedural computed tomography analysis. Procedural and 30-day outcomes were documented in accordance with Valve Academic Research Consortium (VARC)-2 criteria.RESULTS: BASILICA was attempted for single left coronary cusp in 12 patients (80.0%), for single right coronary cusp in 2 patients (13.3%), and for both cusps in 1 patient (6.7%), respectively. The procedure was feasible in 13 patients (86.7%) resulting in effective prevention of coronary obstruction, whilst TAVI was performed without prior successful bioprosthetic leaflet laceration in two patients (13.3%). In one of these patients (6.7%), additional chimney stenting immediately after TAVI was performed. No all-cause deaths or strokes were documented after 30 days.CONCLUSION: The BASILICA technique appears to be a feasible, safe and effective concept to avoid iatrogenic coronary artery obstruction during TAVI in both native and bioprosthetic valves of patients at high or prohibitive risk. ClinicalTrials.gov Identifier: NCT04227002 (Hamburg AoRtic Valve cOhoRt).

U2 - 10.1007/s00392-021-01881-4

DO - 10.1007/s00392-021-01881-4

M3 - SCORING: Journal article

C2 - 34156524

VL - 110

SP - 1900

EP - 1911

JO - CLIN RES CARDIOL

JF - CLIN RES CARDIOL

SN - 1861-0684

IS - 12

ER -