Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials.

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Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials. / Weiss, Christian; Arnold, Dirk; Dellas, Kathrin; Liersch, Torsten; Hipp, Matthias; Fietkau, Rainer; Sauer, Rolf; Hinke, Axel; Rödel, Claus.

In: INT J RADIAT ONCOL, Vol. 78, No. 2, 2, 2010, p. 472-478.

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@article{39fb12d913064988b15504ceb0540fc5,
title = "Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials.",
abstract = "A pooled analysis of three prospective trials of preoperative radiochemotherapy (RCT) for rectal cancer by using oxaliplatin and capecitabine with or without cetuximab was performed to evaluate the impact of additional cetuximab on pathologic complete response (pCR) rates and tumor regression (TRG) grades.",
keywords = "Humans, Male, Female, Middle Aged, Prospective Studies, Sex Factors, Antibodies, Monoclonal administration, dosage, Age Factors, Clinical Trials, Phase II as Topic, Neoplasm Staging, Remission Induction, Analysis of Variance, Antineoplastic Combined Chemotherapy Protocols adverse effects, Fluorouracil administration, Rectal Neoplasms drug therapy, Deoxycytidine administration, Clinical Trials, Phase I as Topic, Combined Modality Therapy methods, Neoadjuvant Therapy adverse effects, Organoplatinum Compounds administration, Humans, Male, Female, Middle Aged, Prospective Studies, Sex Factors, Antibodies, Monoclonal administration, dosage, Age Factors, Clinical Trials, Phase II as Topic, Neoplasm Staging, Remission Induction, Analysis of Variance, Antineoplastic Combined Chemotherapy Protocols adverse effects, Fluorouracil administration, Rectal Neoplasms drug therapy, Deoxycytidine administration, Clinical Trials, Phase I as Topic, Combined Modality Therapy methods, Neoadjuvant Therapy adverse effects, Organoplatinum Compounds administration",
author = "Christian Weiss and Dirk Arnold and Kathrin Dellas and Torsten Liersch and Matthias Hipp and Rainer Fietkau and Rolf Sauer and Axel Hinke and Claus R{\"o}del",
year = "2010",
language = "Deutsch",
volume = "78",
pages = "472--478",
journal = "INT J RADIAT ONCOL",
issn = "0360-3016",
publisher = "Elsevier Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials.

AU - Weiss, Christian

AU - Arnold, Dirk

AU - Dellas, Kathrin

AU - Liersch, Torsten

AU - Hipp, Matthias

AU - Fietkau, Rainer

AU - Sauer, Rolf

AU - Hinke, Axel

AU - Rödel, Claus

PY - 2010

Y1 - 2010

N2 - A pooled analysis of three prospective trials of preoperative radiochemotherapy (RCT) for rectal cancer by using oxaliplatin and capecitabine with or without cetuximab was performed to evaluate the impact of additional cetuximab on pathologic complete response (pCR) rates and tumor regression (TRG) grades.

AB - A pooled analysis of three prospective trials of preoperative radiochemotherapy (RCT) for rectal cancer by using oxaliplatin and capecitabine with or without cetuximab was performed to evaluate the impact of additional cetuximab on pathologic complete response (pCR) rates and tumor regression (TRG) grades.

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Prospective Studies

KW - Sex Factors

KW - Antibodies, Monoclonal administration

KW - dosage

KW - Age Factors

KW - Clinical Trials, Phase II as Topic

KW - Neoplasm Staging

KW - Remission Induction

KW - Analysis of Variance

KW - Antineoplastic Combined Chemotherapy Protocols adverse effects

KW - Fluorouracil administration

KW - Rectal Neoplasms drug therapy

KW - Deoxycytidine administration

KW - Clinical Trials, Phase I as Topic

KW - Combined Modality Therapy methods

KW - Neoadjuvant Therapy adverse effects

KW - Organoplatinum Compounds administration

KW - Humans

KW - Male

KW - Female

KW - Middle Aged

KW - Prospective Studies

KW - Sex Factors

KW - Antibodies, Monoclonal administration

KW - dosage

KW - Age Factors

KW - Clinical Trials, Phase II as Topic

KW - Neoplasm Staging

KW - Remission Induction

KW - Analysis of Variance

KW - Antineoplastic Combined Chemotherapy Protocols adverse effects

KW - Fluorouracil administration

KW - Rectal Neoplasms drug therapy

KW - Deoxycytidine administration

KW - Clinical Trials, Phase I as Topic

KW - Combined Modality Therapy methods

KW - Neoadjuvant Therapy adverse effects

KW - Organoplatinum Compounds administration

M3 - SCORING: Zeitschriftenaufsatz

VL - 78

SP - 472

EP - 478

JO - INT J RADIAT ONCOL

JF - INT J RADIAT ONCOL

SN - 0360-3016

IS - 2

M1 - 2

ER -