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Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series

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Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series. / Butenschoen, Vicki M; Schwendner, Maximilian; Hubertus, Vanessa; Onken, Julia; Koegl, Nikolaus; Mohme, Theresa; Maurer, Stefanie; Boeckh-Behrens, Tobias; Eicker, Sven O; Thomé, Claudius; Vajkoczy, Peter; Czabanka, Marcus; Meyer, Bernhard; Wostrack, Maria.

In: J NEURO-ONCOL, Vol. 161, No. 1, 01.2023, p. 107-115.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Butenschoen, VM, Schwendner, M, Hubertus, V, Onken, J, Koegl, N, Mohme, T, Maurer, S, Boeckh-Behrens, T, Eicker, SO, Thomé, C, Vajkoczy, P, Czabanka, M, Meyer, B & Wostrack, M 2023, 'Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series', J NEURO-ONCOL, vol. 161, no. 1, pp. 107-115. https://doi.org/10.1007/s11060-022-04213-2

APA

Butenschoen, V. M., Schwendner, M., Hubertus, V., Onken, J., Koegl, N., Mohme, T., Maurer, S., Boeckh-Behrens, T., Eicker, S. O., Thomé, C., Vajkoczy, P., Czabanka, M., Meyer, B., & Wostrack, M. (2023). Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series. J NEURO-ONCOL, 161(1), 107-115. https://doi.org/10.1007/s11060-022-04213-2

Vancouver

Butenschoen VM, Schwendner M, Hubertus V, Onken J, Koegl N, Mohme T et al. Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series. J NEURO-ONCOL. 2023 Jan;161(1):107-115. https://doi.org/10.1007/s11060-022-04213-2

Bibtex

@article{6a392985beb64fe987ecd5fc4cb58189,
title = "Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series",
abstract = "PURPOSE: Intradural spinal hemangioblastomas are rare highly hypervascularized benign neoplasms. Surgical resection remains the treatment of choice, with a significant risk of postoperative neurological deterioration. Due to the tumor infrequency, scientific evidence is scarce and limited to case reports and small case series.METHODS: We performed a retrospective multicenter study including five high-volume neurosurgical centers analyzing patients surgically treated for spinal hemangioblastomas between 2006 and 2021. We assessed clinical status, surgical data, preoperative angiograms, and embolization when available. Follow-up records were analyzed, and logistic regression performed to assess possible risk factors for neurological deterioration.RESULTS: We included 60 patients in Germany and Austria. Preoperative angiography was performed in 30% of the cases; 10% of the patients underwent preoperative embolization. Posterior tumor location and presence of a syrinx favored gross total tumor resection (93.8% vs. 83.3% and 97.1% vs. 84%). Preoperative embolization was not associated with postoperative worsening. The clinical outcome revealed a transient postoperative neurological deterioration in 38.3%, depending on symptom duration and preoperative modified McCormick grading, but patients recovered in most cases until follow-up.CONCLUSION: Spinal hemangioblastoma patients significantly benefit from early surgical treatment with only transient postoperative deterioration and complete recovery until follow-up. The performance of preoperative angiograms remains subject to center disparities.",
author = "Butenschoen, {Vicki M} and Maximilian Schwendner and Vanessa Hubertus and Julia Onken and Nikolaus Koegl and Theresa Mohme and Stefanie Maurer and Tobias Boeckh-Behrens and Eicker, {Sven O} and Claudius Thom{\'e} and Peter Vajkoczy and Marcus Czabanka and Bernhard Meyer and Maria Wostrack",
note = "{\textcopyright} 2022. The Author(s).",
year = "2023",
month = jan,
doi = "10.1007/s11060-022-04213-2",
language = "English",
volume = "161",
pages = "107--115",
journal = "J NEURO-ONCOL",
issn = "0167-594X",
publisher = "Kluwer Academic Publishers",
number = "1",

}

RIS

TY - JOUR

T1 - Preoperative angiographic considerations and neurological outcome after surgical treatment of intradural spinal hemangioblastoma: a multicenter retrospective case series

AU - Butenschoen, Vicki M

AU - Schwendner, Maximilian

AU - Hubertus, Vanessa

AU - Onken, Julia

AU - Koegl, Nikolaus

AU - Mohme, Theresa

AU - Maurer, Stefanie

AU - Boeckh-Behrens, Tobias

AU - Eicker, Sven O

AU - Thomé, Claudius

AU - Vajkoczy, Peter

AU - Czabanka, Marcus

AU - Meyer, Bernhard

AU - Wostrack, Maria

N1 - © 2022. The Author(s).

PY - 2023/1

Y1 - 2023/1

N2 - PURPOSE: Intradural spinal hemangioblastomas are rare highly hypervascularized benign neoplasms. Surgical resection remains the treatment of choice, with a significant risk of postoperative neurological deterioration. Due to the tumor infrequency, scientific evidence is scarce and limited to case reports and small case series.METHODS: We performed a retrospective multicenter study including five high-volume neurosurgical centers analyzing patients surgically treated for spinal hemangioblastomas between 2006 and 2021. We assessed clinical status, surgical data, preoperative angiograms, and embolization when available. Follow-up records were analyzed, and logistic regression performed to assess possible risk factors for neurological deterioration.RESULTS: We included 60 patients in Germany and Austria. Preoperative angiography was performed in 30% of the cases; 10% of the patients underwent preoperative embolization. Posterior tumor location and presence of a syrinx favored gross total tumor resection (93.8% vs. 83.3% and 97.1% vs. 84%). Preoperative embolization was not associated with postoperative worsening. The clinical outcome revealed a transient postoperative neurological deterioration in 38.3%, depending on symptom duration and preoperative modified McCormick grading, but patients recovered in most cases until follow-up.CONCLUSION: Spinal hemangioblastoma patients significantly benefit from early surgical treatment with only transient postoperative deterioration and complete recovery until follow-up. The performance of preoperative angiograms remains subject to center disparities.

AB - PURPOSE: Intradural spinal hemangioblastomas are rare highly hypervascularized benign neoplasms. Surgical resection remains the treatment of choice, with a significant risk of postoperative neurological deterioration. Due to the tumor infrequency, scientific evidence is scarce and limited to case reports and small case series.METHODS: We performed a retrospective multicenter study including five high-volume neurosurgical centers analyzing patients surgically treated for spinal hemangioblastomas between 2006 and 2021. We assessed clinical status, surgical data, preoperative angiograms, and embolization when available. Follow-up records were analyzed, and logistic regression performed to assess possible risk factors for neurological deterioration.RESULTS: We included 60 patients in Germany and Austria. Preoperative angiography was performed in 30% of the cases; 10% of the patients underwent preoperative embolization. Posterior tumor location and presence of a syrinx favored gross total tumor resection (93.8% vs. 83.3% and 97.1% vs. 84%). Preoperative embolization was not associated with postoperative worsening. The clinical outcome revealed a transient postoperative neurological deterioration in 38.3%, depending on symptom duration and preoperative modified McCormick grading, but patients recovered in most cases until follow-up.CONCLUSION: Spinal hemangioblastoma patients significantly benefit from early surgical treatment with only transient postoperative deterioration and complete recovery until follow-up. The performance of preoperative angiograms remains subject to center disparities.

U2 - 10.1007/s11060-022-04213-2

DO - 10.1007/s11060-022-04213-2

M3 - SCORING: Journal article

C2 - 36566460

VL - 161

SP - 107

EP - 115

JO - J NEURO-ONCOL

JF - J NEURO-ONCOL

SN - 0167-594X

IS - 1

ER -