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Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease

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Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease. / Campens, Laurence; Baris, Lucia; Scott, Nandita S; Broberg, Craig S; Bondue, Antione; Jondeau, Guillaume; Grewal, Jasmine; Johnson, Mark R; Hall, Roger; De Backer, Julie; Roos-Hesselink, Jolien W; ROPAC investigators group.

In: HEART, Vol. 107, No. 21, 11.2021, p. 1704-1709.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Campens, L, Baris, L, Scott, NS, Broberg, CS, Bondue, A, Jondeau, G, Grewal, J, Johnson, MR, Hall, R, De Backer, J, Roos-Hesselink, JW & ROPAC investigators group 2021, 'Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease', HEART, vol. 107, no. 21, pp. 1704-1709. https://doi.org/10.1136/heartjnl-2020-318183

APA

Campens, L., Baris, L., Scott, N. S., Broberg, C. S., Bondue, A., Jondeau, G., Grewal, J., Johnson, M. R., Hall, R., De Backer, J., Roos-Hesselink, J. W., & ROPAC investigators group (2021). Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease. HEART, 107(21), 1704-1709. https://doi.org/10.1136/heartjnl-2020-318183

Vancouver

Campens L, Baris L, Scott NS, Broberg CS, Bondue A, Jondeau G et al. Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease. HEART. 2021 Nov;107(21):1704-1709. https://doi.org/10.1136/heartjnl-2020-318183

Bibtex

@article{c69488dfc3bc4306b74d4b361fa3787e,
title = "Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease",
abstract = "BACKGROUND: Cardiovascular disease is the leading cause of death during pregnancy with thoracic aortic dissection being one of the main causes. Thoracic aortic disease is commonly related to hereditary disorders and congenital heart malformations such as bicuspid aortic valve (BAV). Pregnancy is considered a high risk period in women with underlying aortopathy.METHODS: The ESC EORP Registry Of Pregnancy And Cardiac disease (ROPAC) is a prospective global registry that enrolled 5739 women with pre-existing cardiac disease. With this analysis, we aim to study the maternal and fetal outcome of pregnancy in women with thoracic aortic disease.RESULTS: Thoracic aortic disease was reported in 189 women (3.3%). Half of them were patients with Marfan syndrome (MFS), 26% had a BAV, 8% Turner syndrome, 2% vascular Ehlers-Danlos syndrome and 11% had no underlying genetic defect or associated congenital heart defect. Aortic dilatation was reported in 58% of patients and 6% had a history of aortic dissection. Four patients, of whom three were patients with MFS, had an acute aortic dissection (three type A and one type B aortic dissection) without maternal or fetal mortality. No complications occurred in women with a history of aortic dissection. There was no significant difference in median fetal birth weight if treated with a beta-blocker or not (2960 g (2358-3390 g) vs 3270 g (2750-3570 g), p value 0.25).CONCLUSION: This ancillary analysis provides the largest prospective data review on pregnancy risk for patients with thoracic aortic disease. Overall pregnancy outcomes in women with thoracic aortic disease followed according to current guidelines are good.",
keywords = "Adult, Aorta, Thoracic, Aortic Diseases/epidemiology, Cause of Death/trends, Comorbidity, Female, Global Health, Heart Diseases/epidemiology, Humans, Incidence, Infant, Newborn, Pregnancy, Pregnancy Complications, Cardiovascular, Pregnancy Outcome, Prospective Studies, Registries, Survival Rate/trends",
author = "Laurence Campens and Lucia Baris and Scott, {Nandita S} and Broberg, {Craig S} and Antione Bondue and Guillaume Jondeau and Jasmine Grewal and Johnson, {Mark R} and Roger Hall and {De Backer}, Julie and Roos-Hesselink, {Jolien W} and {ROPAC investigators group}",
note = "{\textcopyright} Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",
year = "2021",
month = nov,
doi = "10.1136/heartjnl-2020-318183",
language = "English",
volume = "107",
pages = "1704--1709",
journal = "HEART",
issn = "1355-6037",
publisher = "BMJ PUBLISHING GROUP",
number = "21",

}

RIS

TY - JOUR

T1 - Pregnancy outcome in thoracic aortic disease data from the Registry Of Pregnancy And Cardiac disease

AU - Campens, Laurence

AU - Baris, Lucia

AU - Scott, Nandita S

AU - Broberg, Craig S

AU - Bondue, Antione

AU - Jondeau, Guillaume

AU - Grewal, Jasmine

AU - Johnson, Mark R

AU - Hall, Roger

AU - De Backer, Julie

AU - Roos-Hesselink, Jolien W

AU - ROPAC investigators group

N1 - © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2021/11

Y1 - 2021/11

N2 - BACKGROUND: Cardiovascular disease is the leading cause of death during pregnancy with thoracic aortic dissection being one of the main causes. Thoracic aortic disease is commonly related to hereditary disorders and congenital heart malformations such as bicuspid aortic valve (BAV). Pregnancy is considered a high risk period in women with underlying aortopathy.METHODS: The ESC EORP Registry Of Pregnancy And Cardiac disease (ROPAC) is a prospective global registry that enrolled 5739 women with pre-existing cardiac disease. With this analysis, we aim to study the maternal and fetal outcome of pregnancy in women with thoracic aortic disease.RESULTS: Thoracic aortic disease was reported in 189 women (3.3%). Half of them were patients with Marfan syndrome (MFS), 26% had a BAV, 8% Turner syndrome, 2% vascular Ehlers-Danlos syndrome and 11% had no underlying genetic defect or associated congenital heart defect. Aortic dilatation was reported in 58% of patients and 6% had a history of aortic dissection. Four patients, of whom three were patients with MFS, had an acute aortic dissection (three type A and one type B aortic dissection) without maternal or fetal mortality. No complications occurred in women with a history of aortic dissection. There was no significant difference in median fetal birth weight if treated with a beta-blocker or not (2960 g (2358-3390 g) vs 3270 g (2750-3570 g), p value 0.25).CONCLUSION: This ancillary analysis provides the largest prospective data review on pregnancy risk for patients with thoracic aortic disease. Overall pregnancy outcomes in women with thoracic aortic disease followed according to current guidelines are good.

AB - BACKGROUND: Cardiovascular disease is the leading cause of death during pregnancy with thoracic aortic dissection being one of the main causes. Thoracic aortic disease is commonly related to hereditary disorders and congenital heart malformations such as bicuspid aortic valve (BAV). Pregnancy is considered a high risk period in women with underlying aortopathy.METHODS: The ESC EORP Registry Of Pregnancy And Cardiac disease (ROPAC) is a prospective global registry that enrolled 5739 women with pre-existing cardiac disease. With this analysis, we aim to study the maternal and fetal outcome of pregnancy in women with thoracic aortic disease.RESULTS: Thoracic aortic disease was reported in 189 women (3.3%). Half of them were patients with Marfan syndrome (MFS), 26% had a BAV, 8% Turner syndrome, 2% vascular Ehlers-Danlos syndrome and 11% had no underlying genetic defect or associated congenital heart defect. Aortic dilatation was reported in 58% of patients and 6% had a history of aortic dissection. Four patients, of whom three were patients with MFS, had an acute aortic dissection (three type A and one type B aortic dissection) without maternal or fetal mortality. No complications occurred in women with a history of aortic dissection. There was no significant difference in median fetal birth weight if treated with a beta-blocker or not (2960 g (2358-3390 g) vs 3270 g (2750-3570 g), p value 0.25).CONCLUSION: This ancillary analysis provides the largest prospective data review on pregnancy risk for patients with thoracic aortic disease. Overall pregnancy outcomes in women with thoracic aortic disease followed according to current guidelines are good.

KW - Adult

KW - Aorta, Thoracic

KW - Aortic Diseases/epidemiology

KW - Cause of Death/trends

KW - Comorbidity

KW - Female

KW - Global Health

KW - Heart Diseases/epidemiology

KW - Humans

KW - Incidence

KW - Infant, Newborn

KW - Pregnancy

KW - Pregnancy Complications, Cardiovascular

KW - Pregnancy Outcome

KW - Prospective Studies

KW - Registries

KW - Survival Rate/trends

U2 - 10.1136/heartjnl-2020-318183

DO - 10.1136/heartjnl-2020-318183

M3 - SCORING: Journal article

C2 - 33468574

VL - 107

SP - 1704

EP - 1709

JO - HEART

JF - HEART

SN - 1355-6037

IS - 21

ER -