Predictors of inflammatory breast diseases during lactation--results of a cohort study.

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Predictors of inflammatory breast diseases during lactation--results of a cohort study. / Wöckel, Achim; Beggel, Anna; Rücke, Miriam; Abou-Dakn, Michael; Arck, Petra.

In: AM J REPROD IMMUNOL, Vol. 63, No. 1, 1, 2010, p. 28-37.

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@article{ff5bf12225ad490db48f34a54d0da485,
title = "Predictors of inflammatory breast diseases during lactation--results of a cohort study.",
abstract = "PROBLEM: Inflammatory breast diseases during lactation are major reasons for early weaning. METHOD OF STUDY: A prospective cohort study was performed to examine the association between stress and inflammatory breast diseases. Psychometric data, cytokine levels in breast milk and blood samples were analysed postpartum (T1). Psychometric data and course of breast feeding were evaluated twelve weeks later (T2). Patients were divided into case- and control-groups (according to the presence of breast diseases). RESULTS: Mothers of the case group (n = 23) were significantly older and showed significantly increased stress levels between T1 and T2 compared with the control group (n = 43). Leucocytes in the postpartum blood count were significantly decreased in the case group. There were no significant differences between groups in the concentrations of Th-1- and Th-2-cytokines in breast milk postpartum. CONCLUSION: Higher maternal age, postpartum increase in stress perception and low number of leucocytes are associated with a higher incidence of inflammatory breast diseases. Further studies must examine the causality of this effect.",
author = "Achim W{\"o}ckel and Anna Beggel and Miriam R{\"u}cke and Michael Abou-Dakn and Petra Arck",
year = "2010",
doi = "10.1111/j.1600-0897.2009.00762.x",
language = "Deutsch",
volume = "63",
pages = "28--37",
journal = "AM J REPROD IMMUNOL",
issn = "1046-7408",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Predictors of inflammatory breast diseases during lactation--results of a cohort study.

AU - Wöckel, Achim

AU - Beggel, Anna

AU - Rücke, Miriam

AU - Abou-Dakn, Michael

AU - Arck, Petra

PY - 2010

Y1 - 2010

N2 - PROBLEM: Inflammatory breast diseases during lactation are major reasons for early weaning. METHOD OF STUDY: A prospective cohort study was performed to examine the association between stress and inflammatory breast diseases. Psychometric data, cytokine levels in breast milk and blood samples were analysed postpartum (T1). Psychometric data and course of breast feeding were evaluated twelve weeks later (T2). Patients were divided into case- and control-groups (according to the presence of breast diseases). RESULTS: Mothers of the case group (n = 23) were significantly older and showed significantly increased stress levels between T1 and T2 compared with the control group (n = 43). Leucocytes in the postpartum blood count were significantly decreased in the case group. There were no significant differences between groups in the concentrations of Th-1- and Th-2-cytokines in breast milk postpartum. CONCLUSION: Higher maternal age, postpartum increase in stress perception and low number of leucocytes are associated with a higher incidence of inflammatory breast diseases. Further studies must examine the causality of this effect.

AB - PROBLEM: Inflammatory breast diseases during lactation are major reasons for early weaning. METHOD OF STUDY: A prospective cohort study was performed to examine the association between stress and inflammatory breast diseases. Psychometric data, cytokine levels in breast milk and blood samples were analysed postpartum (T1). Psychometric data and course of breast feeding were evaluated twelve weeks later (T2). Patients were divided into case- and control-groups (according to the presence of breast diseases). RESULTS: Mothers of the case group (n = 23) were significantly older and showed significantly increased stress levels between T1 and T2 compared with the control group (n = 43). Leucocytes in the postpartum blood count were significantly decreased in the case group. There were no significant differences between groups in the concentrations of Th-1- and Th-2-cytokines in breast milk postpartum. CONCLUSION: Higher maternal age, postpartum increase in stress perception and low number of leucocytes are associated with a higher incidence of inflammatory breast diseases. Further studies must examine the causality of this effect.

U2 - 10.1111/j.1600-0897.2009.00762.x

DO - 10.1111/j.1600-0897.2009.00762.x

M3 - SCORING: Zeitschriftenaufsatz

VL - 63

SP - 28

EP - 37

JO - AM J REPROD IMMUNOL

JF - AM J REPROD IMMUNOL

SN - 1046-7408

IS - 1

M1 - 1

ER -