Predictive value of interferon-γ release assays and tuberculin skin testing for progression from latent TB infection to disease state: a meta-analysis.
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Predictive value of interferon-γ release assays and tuberculin skin testing for progression from latent TB infection to disease state: a meta-analysis. / Diel, Roland; Loddenkemper, Robert; Nienhaus, Albert.
In: CHEST, Vol. 142, No. 1, 1, 2012, p. 63-75.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Predictive value of interferon-γ release assays and tuberculin skin testing for progression from latent TB infection to disease state: a meta-analysis.
AU - Diel, Roland
AU - Loddenkemper, Robert
AU - Nienhaus, Albert
PY - 2012
Y1 - 2012
N2 - Given the current lack of effective vaccines against TB, the accuracy of screening tests for determining or excluding latent TB infection (LTBI) is decisive in effective TB control. This meta-analysis critically appraises studies investigating the positive and the negative predictive value (PPV and NPV, respectively) from a test-determined LTBI state for progression to active TB of interferon-? release assays (IGRAs) and the tuberculin skin test (TST).
AB - Given the current lack of effective vaccines against TB, the accuracy of screening tests for determining or excluding latent TB infection (LTBI) is decisive in effective TB control. This meta-analysis critically appraises studies investigating the positive and the negative predictive value (PPV and NPV, respectively) from a test-determined LTBI state for progression to active TB of interferon-? release assays (IGRAs) and the tuberculin skin test (TST).
KW - Humans
KW - Risk Factors
KW - Predictive Value of Tests
KW - Disease Progression
KW - Interferon-gamma Release Tests/standards
KW - Latent Tuberculosis/diagnosis
KW - Tuberculin Test/standards
KW - Tuberculosis/diagnosis/epidemiology
KW - Humans
KW - Risk Factors
KW - Predictive Value of Tests
KW - Disease Progression
KW - Interferon-gamma Release Tests/standards
KW - Latent Tuberculosis/diagnosis
KW - Tuberculin Test/standards
KW - Tuberculosis/diagnosis/epidemiology
M3 - SCORING: Journal article
VL - 142
SP - 63
EP - 75
JO - CHEST
JF - CHEST
SN - 0012-3692
IS - 1
M1 - 1
ER -