Predictive value of HER2 serum levels in patients treated with lapatinib or trastuzumab -- a translational project in the neoadjuvant GeparQuinto trial.

  • Isabell Witzel
  • S Loibl
  • G von Minckwitz
  • H Eidtmann
  • T Fehm
  • F Khandan
  • S Schmatloch
  • M Hauschild
  • J Bischoff
  • P A Fasching
  • C Mau
  • C Schem
  • B Rack
  • I Meinhold-Heerlein
  • C Liedtke
  • T Karn
  • J Huober
  • Christine Gräfin Zu Eulenburg
  • Y Issa-Nummer
  • M Untch
  • Volkmar Müller

Abstract

We were able to demonstrate a predictive value of serum HER2 (sHER2) in patients receiving trastuzumab in the neoadjuvant GeparQuattro trial. However, the role of sHER2 in patients receiving neoadjuvant therapy (NT) with lapatinib is still unclear.

Bibliographical data

Original languageEnglish
Article number6
ISSN0007-0920
Publication statusPublished - 2012
pubmed 22892393