Prediction of left ventricular remodeling and analysis of infarct resorption in patients with reperfused myocardial infarcts by using contrast-enhanced MR imaging.
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Prediction of left ventricular remodeling and analysis of infarct resorption in patients with reperfused myocardial infarcts by using contrast-enhanced MR imaging. / Lund, Gunnar; Stork, Alexander; Müllerleile, Kai; Barmeyer, Achim; Bansmann, Paul Martin; Knefel, Meike; Schlichting, Ulrike; Müller, Martin; Verde, Pablo E; Adam, Gerhard; Meinertz, Thomas; Saeed, Maythem.
In: RADIOLOGY, Vol. 245, No. 1, 1, 2007, p. 95-102.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Prediction of left ventricular remodeling and analysis of infarct resorption in patients with reperfused myocardial infarcts by using contrast-enhanced MR imaging.
AU - Lund, Gunnar
AU - Stork, Alexander
AU - Müllerleile, Kai
AU - Barmeyer, Achim
AU - Bansmann, Paul Martin
AU - Knefel, Meike
AU - Schlichting, Ulrike
AU - Müller, Martin
AU - Verde, Pablo E
AU - Adam, Gerhard
AU - Meinertz, Thomas
AU - Saeed, Maythem
PY - 2007
Y1 - 2007
N2 - PURPOSE: To prospectively evaluate the accuracy of clinical and cardiac magnetic resonance (MR) imaging parameters for predicting left ventricular (LV) remodeling by using follow-up imaging as reference standard, and to prospectively evaluate infarct resorption in patients with reperfused first myocardial infarcts. MATERIALS AND METHODS: The study was approved by the institutional ethics committee and all patients gave written informed consent. In 55 patients (48 men, seven women; mean age+/-standard deviation, 56 years+/-13), contrast material-enhanced and cine MR imaging were performed 5 days+/-3 and 8 months+/-3 after myocardial infarction (MI). Microvascular obstruction (MO) and infarct size were estimated at first-pass enhancement (FPE) and delayed enhancement (DE) MR, respectively. Remodeling was defined as an increase in LV end-diastolic volume index of 20% or higher at follow-up. Differences in continuous and categorical data were analyzed by using Student t test and Fischer exact test as appropriate. RESULTS: Patients with remodeling (n=13, 24%) had higher creatine kinase MB (P
AB - PURPOSE: To prospectively evaluate the accuracy of clinical and cardiac magnetic resonance (MR) imaging parameters for predicting left ventricular (LV) remodeling by using follow-up imaging as reference standard, and to prospectively evaluate infarct resorption in patients with reperfused first myocardial infarcts. MATERIALS AND METHODS: The study was approved by the institutional ethics committee and all patients gave written informed consent. In 55 patients (48 men, seven women; mean age+/-standard deviation, 56 years+/-13), contrast material-enhanced and cine MR imaging were performed 5 days+/-3 and 8 months+/-3 after myocardial infarction (MI). Microvascular obstruction (MO) and infarct size were estimated at first-pass enhancement (FPE) and delayed enhancement (DE) MR, respectively. Remodeling was defined as an increase in LV end-diastolic volume index of 20% or higher at follow-up. Differences in continuous and categorical data were analyzed by using Student t test and Fischer exact test as appropriate. RESULTS: Patients with remodeling (n=13, 24%) had higher creatine kinase MB (P
M3 - SCORING: Zeitschriftenaufsatz
VL - 245
SP - 95
EP - 102
JO - RADIOLOGY
JF - RADIOLOGY
SN - 0033-8419
IS - 1
M1 - 1
ER -
