Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa.

  • P E J Van Der Meijden
  • M Van Schilfgaarde
  • R Van Oerle
  • Thomas Renné
  • H Ten Cate
  • H M H Spronk

Abstract

The procoagulant properties of microparticles (MPs) are due to the of the presence of phosphatidylserine (PS) and tissue factor (TF) on their surface. The latter has been demonstrated especially on MPs derived from monocytes.

Bibliographical data

Original languageEnglish
Article number7
ISSN1538-7933
Publication statusPublished - 2012
pubmed 22537188