Plasma S100β is not a useful biomarker for tumor burden in neurofibromatosis.
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Plasma S100β is not a useful biomarker for tumor burden in neurofibromatosis. / Smith, Miriam J; Esparza, Sonia; Merker, Vanessa L; Muzikansky, Alona; Bredella, Miriam A; Harris, Gordon J; Kassarjian, Ara; Cai, Wenli; Walker, James A; Mautner, Viktor Felix; Plotkin, Scott R.
In: CLIN BIOCHEM, Vol. 46, No. 7-8, 7-8, 2013, p. 698-700.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Plasma S100β is not a useful biomarker for tumor burden in neurofibromatosis.
AU - Smith, Miriam J
AU - Esparza, Sonia
AU - Merker, Vanessa L
AU - Muzikansky, Alona
AU - Bredella, Miriam A
AU - Harris, Gordon J
AU - Kassarjian, Ara
AU - Cai, Wenli
AU - Walker, James A
AU - Mautner, Viktor Felix
AU - Plotkin, Scott R
PY - 2013
Y1 - 2013
N2 - Neurofibromatosis 1 (NF1), NF2, and schwannomatosis are characterized by a predisposition to develop multiple neurofibromas and schwannomas. Currently, there is no blood test to estimate tumor burden in patients with these disorders. We explored whether S100? would act as a biomarker of tumor burden in NF since S100? is a classic immunohistochemical marker of astrocytes, oligodendrocytes and Schwann cells and a small study showed S100? concentrations correlate with the volume of vestibular schwannomas.
AB - Neurofibromatosis 1 (NF1), NF2, and schwannomatosis are characterized by a predisposition to develop multiple neurofibromas and schwannomas. Currently, there is no blood test to estimate tumor burden in patients with these disorders. We explored whether S100? would act as a biomarker of tumor burden in NF since S100? is a classic immunohistochemical marker of astrocytes, oligodendrocytes and Schwann cells and a small study showed S100? concentrations correlate with the volume of vestibular schwannomas.
M3 - SCORING: Journal article
VL - 46
SP - 698
EP - 700
JO - CLIN BIOCHEM
JF - CLIN BIOCHEM
SN - 0009-9120
IS - 7-8
M1 - 7-8
ER -