Plasma calcium oxalate supersaturation in children with primary hyperoxaluria and end-stage renal failure.

  • B Hoppe
  • Markus J. Kemper
  • A Bökenkamp
  • A A Portale
  • R A Cohn
  • C B Langman

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Abstract

Children with primary hyperoxaluria type 1 (PH 1) are at great risk to develop systemic oxalosis in end-stage renal disease (ESRD), as endogenous oxalate production exceeds oxalate removal by dialytic therapy. As oxalate accumulates, calcium oxalate (CaOx) tissue deposition occurs. Children with other causes of ESRD, however, are not prone to CaOx deposition despite elevated plasma oxalate (POx) levels.

Bibliographical data

Original languageEnglish
Article number1
ISSN0085-2538
Publication statusPublished - 1999
pubmed 10411702