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PillCamColon2 after incomplete colonoscopy - A prospective multicenter study

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PillCamColon2 after incomplete colonoscopy - A prospective multicenter study. / Baltes, Peter; Bota, Marc; Albert, Jörg; Philipper, Michael; Hörster, Hans-Georg; Hagenmüller, Friedrich; Steinbrück, Ingo; Jakobs, Ralf; Bechtler, Matthias; Hartmann, Dirk; Neuhaus, Horst; Charton, Jean-Pierre; Mayershofer, Rupert; Hohn, Horst; Rösch, Thomas; Groth, Stefan; Nowak, Tanja; Wohlmuth, Peter; Keuchel, Martin.

In: WORLD J GASTROENTERO, Vol. 24, No. 31, 21.08.2018, p. 3556-3566.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Baltes, P, Bota, M, Albert, J, Philipper, M, Hörster, H-G, Hagenmüller, F, Steinbrück, I, Jakobs, R, Bechtler, M, Hartmann, D, Neuhaus, H, Charton, J-P, Mayershofer, R, Hohn, H, Rösch, T, Groth, S, Nowak, T, Wohlmuth, P & Keuchel, M 2018, 'PillCamColon2 after incomplete colonoscopy - A prospective multicenter study', WORLD J GASTROENTERO, vol. 24, no. 31, pp. 3556-3566. https://doi.org/10.3748/wjg.v24.i31.3556

APA

Baltes, P., Bota, M., Albert, J., Philipper, M., Hörster, H-G., Hagenmüller, F., Steinbrück, I., Jakobs, R., Bechtler, M., Hartmann, D., Neuhaus, H., Charton, J-P., Mayershofer, R., Hohn, H., Rösch, T., Groth, S., Nowak, T., Wohlmuth, P., & Keuchel, M. (2018). PillCamColon2 after incomplete colonoscopy - A prospective multicenter study. WORLD J GASTROENTERO, 24(31), 3556-3566. https://doi.org/10.3748/wjg.v24.i31.3556

Vancouver

Baltes P, Bota M, Albert J, Philipper M, Hörster H-G, Hagenmüller F et al. PillCamColon2 after incomplete colonoscopy - A prospective multicenter study. WORLD J GASTROENTERO. 2018 Aug 21;24(31):3556-3566. https://doi.org/10.3748/wjg.v24.i31.3556

Bibtex

@article{60235e8da6d5499eaeefccdae39286c5,
title = "PillCamColon2 after incomplete colonoscopy - A prospective multicenter study",
abstract = "AIM: To evaluate the ability of PillCamColon2 to visualize colonic segments missed by incomplete optical colonoscopy (OC) and to assess the diagnostic yield.METHODS: This prospective multicentre study included 81 patients from nine centres who underwent second-generation colon capsule endoscopy (CCE) following incomplete OC performed by an experienced gastroenterologist (> 1000 colonoscopies). Patients with stenosis were excluded. According to patient preferences, CCE was performed the following day (protocol A) after staying on clear liquids and 0.75 L Moviprep in the morning or within 30 d after new split-dose Moviprep (protocol B). Boosts consisted of 0.75 L and 0.25 L Moviprep, and phospho-soda was given as a rescue if the capsule was not excreted after seven hours.RESULTS: Seventy-four patients were analysed (51% of them in group A; 49% in group B). Bowel cleansing was adequate in 67% of cases, and CCE could visualize colonic segments missed by incomplete colonoscopy in 90% of patients under protocol A and 97% of patients under protocol B (P = 0.35, n.s.). Significant polyps including adenocarcinoma were detected in 24% of cases. Detection rates for all polyps and significant polyps per patient were similar in both protocols. Polyps were found predominantly in the right colon (86%) in segments that were not reached by OC. Extracolonic findings - such as reflux esophagitis, suspected Barrett esophagus, upper GI-bleeding, gastric polyps, gastric erosions and angiectasia - were detected in eight patients. PillCamColon2 capsule was retained in the ileum of one patient (1.4%) without symptoms and removed during an uneventful resection for unknown Crohn's disease that was diagnosed as the cause of anemia, which was the indication for colonoscopy. CCE was well tolerated. One patient suffered from self-limiting vomiting after consuming the phospho-soda.CONCLUSION: Second-generation CCE using a low-volume preparation is useful after incomplete OC, and it allows for the detection of additional relevant findings, but cleansing efficiency could be improved.",
keywords = "Journal Article",
author = "Peter Baltes and Marc Bota and J{\"o}rg Albert and Michael Philipper and Hans-Georg H{\"o}rster and Friedrich Hagenm{\"u}ller and Ingo Steinbr{\"u}ck and Ralf Jakobs and Matthias Bechtler and Dirk Hartmann and Horst Neuhaus and Jean-Pierre Charton and Rupert Mayershofer and Horst Hohn and Thomas R{\"o}sch and Stefan Groth and Tanja Nowak and Peter Wohlmuth and Martin Keuchel",
year = "2018",
month = aug,
day = "21",
doi = "10.3748/wjg.v24.i31.3556",
language = "English",
volume = "24",
pages = "3556--3566",
journal = "WORLD J GASTROENTERO",
issn = "1007-9327",
publisher = "WJG Press",
number = "31",

}

RIS

TY - JOUR

T1 - PillCamColon2 after incomplete colonoscopy - A prospective multicenter study

AU - Baltes, Peter

AU - Bota, Marc

AU - Albert, Jörg

AU - Philipper, Michael

AU - Hörster, Hans-Georg

AU - Hagenmüller, Friedrich

AU - Steinbrück, Ingo

AU - Jakobs, Ralf

AU - Bechtler, Matthias

AU - Hartmann, Dirk

AU - Neuhaus, Horst

AU - Charton, Jean-Pierre

AU - Mayershofer, Rupert

AU - Hohn, Horst

AU - Rösch, Thomas

AU - Groth, Stefan

AU - Nowak, Tanja

AU - Wohlmuth, Peter

AU - Keuchel, Martin

PY - 2018/8/21

Y1 - 2018/8/21

N2 - AIM: To evaluate the ability of PillCamColon2 to visualize colonic segments missed by incomplete optical colonoscopy (OC) and to assess the diagnostic yield.METHODS: This prospective multicentre study included 81 patients from nine centres who underwent second-generation colon capsule endoscopy (CCE) following incomplete OC performed by an experienced gastroenterologist (> 1000 colonoscopies). Patients with stenosis were excluded. According to patient preferences, CCE was performed the following day (protocol A) after staying on clear liquids and 0.75 L Moviprep in the morning or within 30 d after new split-dose Moviprep (protocol B). Boosts consisted of 0.75 L and 0.25 L Moviprep, and phospho-soda was given as a rescue if the capsule was not excreted after seven hours.RESULTS: Seventy-four patients were analysed (51% of them in group A; 49% in group B). Bowel cleansing was adequate in 67% of cases, and CCE could visualize colonic segments missed by incomplete colonoscopy in 90% of patients under protocol A and 97% of patients under protocol B (P = 0.35, n.s.). Significant polyps including adenocarcinoma were detected in 24% of cases. Detection rates for all polyps and significant polyps per patient were similar in both protocols. Polyps were found predominantly in the right colon (86%) in segments that were not reached by OC. Extracolonic findings - such as reflux esophagitis, suspected Barrett esophagus, upper GI-bleeding, gastric polyps, gastric erosions and angiectasia - were detected in eight patients. PillCamColon2 capsule was retained in the ileum of one patient (1.4%) without symptoms and removed during an uneventful resection for unknown Crohn's disease that was diagnosed as the cause of anemia, which was the indication for colonoscopy. CCE was well tolerated. One patient suffered from self-limiting vomiting after consuming the phospho-soda.CONCLUSION: Second-generation CCE using a low-volume preparation is useful after incomplete OC, and it allows for the detection of additional relevant findings, but cleansing efficiency could be improved.

AB - AIM: To evaluate the ability of PillCamColon2 to visualize colonic segments missed by incomplete optical colonoscopy (OC) and to assess the diagnostic yield.METHODS: This prospective multicentre study included 81 patients from nine centres who underwent second-generation colon capsule endoscopy (CCE) following incomplete OC performed by an experienced gastroenterologist (> 1000 colonoscopies). Patients with stenosis were excluded. According to patient preferences, CCE was performed the following day (protocol A) after staying on clear liquids and 0.75 L Moviprep in the morning or within 30 d after new split-dose Moviprep (protocol B). Boosts consisted of 0.75 L and 0.25 L Moviprep, and phospho-soda was given as a rescue if the capsule was not excreted after seven hours.RESULTS: Seventy-four patients were analysed (51% of them in group A; 49% in group B). Bowel cleansing was adequate in 67% of cases, and CCE could visualize colonic segments missed by incomplete colonoscopy in 90% of patients under protocol A and 97% of patients under protocol B (P = 0.35, n.s.). Significant polyps including adenocarcinoma were detected in 24% of cases. Detection rates for all polyps and significant polyps per patient were similar in both protocols. Polyps were found predominantly in the right colon (86%) in segments that were not reached by OC. Extracolonic findings - such as reflux esophagitis, suspected Barrett esophagus, upper GI-bleeding, gastric polyps, gastric erosions and angiectasia - were detected in eight patients. PillCamColon2 capsule was retained in the ileum of one patient (1.4%) without symptoms and removed during an uneventful resection for unknown Crohn's disease that was diagnosed as the cause of anemia, which was the indication for colonoscopy. CCE was well tolerated. One patient suffered from self-limiting vomiting after consuming the phospho-soda.CONCLUSION: Second-generation CCE using a low-volume preparation is useful after incomplete OC, and it allows for the detection of additional relevant findings, but cleansing efficiency could be improved.

KW - Journal Article

U2 - 10.3748/wjg.v24.i31.3556

DO - 10.3748/wjg.v24.i31.3556

M3 - SCORING: Journal article

C2 - 30131662

VL - 24

SP - 3556

EP - 3566

JO - WORLD J GASTROENTERO

JF - WORLD J GASTROENTERO

SN - 1007-9327

IS - 31

ER -