Photo refractive Keratectomy with Adjuvant Application of Mitomycin C

PRK is a refractive surface ablation and is a good option when LASIK is not possible, especially to avoid flap associated complications. After removing the epithelium an excimer laser treatment is performed. Postoperative application of mitomycin C is possible to modulate the wound healing and to reduce the postoperative occurrence of haze. Adverse side effects of MMC are associated with its concentration, time of application and application strategy. In our protocol we apply MMC between 15-30 seconds with a sponge. Especially for difficult treatments, re-treatments or scarred tissue the application of MMC is advisable.