Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.
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Abstract
Increased lipid accumulation in cells and tissues is a key phenomenon in the development of obesity, insulin resistance, and atherosclerosis. In the regulation of lipid content of cells and tissues the SREBPs play a dominant role as transcription factors.
Bibliographical data
| Original language | German |
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| Article number | 1 |
| ISSN | 0021-9150 |
| Publication status | Published - 2010 |
| pubmed | 20863500 |
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