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Percutaneous mitral valve repair with the MitraClip system according to the predicted risk by the logistic EuroSCORE: preliminary results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry

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Percutaneous mitral valve repair with the MitraClip system according to the predicted risk by the logistic EuroSCORE: preliminary results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. / Wiebe, Jens; Franke, Jennifer; Lubos, Edith; Boekstegers, Peter; Schillinger, Wolfgang; Ouarrak, Taoufik; May, Andreas E; Eggebrecht, Holger; Kuck, Karl-Heinz; Baldus, Stephan; Senges, Jochen; Sievert, Horst; German Transcatheter Mitral Valve Intervention (TRAMI) investigators.

In: CATHETER CARDIO INTE, Vol. 84, No. 4, 01.10.2014, p. 591-598.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Wiebe, J, Franke, J, Lubos, E, Boekstegers, P, Schillinger, W, Ouarrak, T, May, AE, Eggebrecht, H, Kuck, K-H, Baldus, S, Senges, J, Sievert, H & German Transcatheter Mitral Valve Intervention (TRAMI) investigators 2014, 'Percutaneous mitral valve repair with the MitraClip system according to the predicted risk by the logistic EuroSCORE: preliminary results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry', CATHETER CARDIO INTE, vol. 84, no. 4, pp. 591-598. https://doi.org/10.1002/ccd.25493

APA

Wiebe, J., Franke, J., Lubos, E., Boekstegers, P., Schillinger, W., Ouarrak, T., May, A. E., Eggebrecht, H., Kuck, K-H., Baldus, S., Senges, J., Sievert, H., & German Transcatheter Mitral Valve Intervention (TRAMI) investigators (2014). Percutaneous mitral valve repair with the MitraClip system according to the predicted risk by the logistic EuroSCORE: preliminary results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. CATHETER CARDIO INTE, 84(4), 591-598. https://doi.org/10.1002/ccd.25493

Vancouver

Wiebe J, Franke J, Lubos E, Boekstegers P, Schillinger W, Ouarrak T et al. Percutaneous mitral valve repair with the MitraClip system according to the predicted risk by the logistic EuroSCORE: preliminary results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. CATHETER CARDIO INTE. 2014 Oct 1;84(4):591-598. https://doi.org/10.1002/ccd.25493

Bibtex

@article{574a98fad0e84806993724b5b7da713b,
title = "Percutaneous mitral valve repair with the MitraClip system according to the predicted risk by the logistic EuroSCORE: preliminary results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry",
abstract = "OBJECTIVE: To evaluate in-hospital and short-term outcomes of percutaneous mitral valve repair according to patients' logistic EuroSCORE (logEuroSCORE) in a multicenter registryBACKGROUND: The logEuroSCORE is an established tool to predict the risk of mortality during cardiac surgery. In high-risk patients percutaneous mitral valve repair with the MitraClip system represents a less-invasive alternativeMETHODS: Data from 1002 patients, who underwent percutaneous mitral valve repair with the MitraClip system, were analyzed in the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. A logEuroSCORE (mortality risk in %) ≥ 20 was considered high riskRESULTS: Of all patients, 557 (55.6%) had a logEuroSCORE ≥ 20. Implantation of the MitraClip was successful in 95.5 % (942/986) patients. Moderate residual mitral valve regurgitation was more often detected in patients with a logEuroSCORE ≥ 20 (23.8% vs. 17.1%, respectively, P < 0.05). In patients with a logEuroSCORE ≥ 20 the procedural complication rate was 8.9% (vs. 6.4, n.s.) and the in-hospital MACCE rate 4.9% (vs. 1.4% P < 0.01). The in-hospital mortality rate in patients with a logEuroSCORE ≥ 20 and logEuroSCORE < 20 was 4.3 and 1.1%, respectively (P ≤ 0.01) CONCLUSION: Percutaneous mitral valve repair with the MitraClip system is feasible in patients with a logEuroSCORE ≥ 20 with similar procedural results compared to patients with lower predicted risk. Although mortality was four times higher than in patients with logEuroSCORE < 20, mortality in high risk patients was lower than predicted. In those with a logEuroSCORE ≥ 20, moderate residual mitral valve regurgitation was more frequent.",
keywords = "Aged, Aged, 80 and over, Cardiac Catheterization/adverse effects, Chi-Square Distribution, Feasibility Studies, Female, Germany, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation/adverse effects, Hospital Mortality, Humans, Logistic Models, Male, Mitral Valve/physiopathology, Mitral Valve Insufficiency/diagnosis, Patient Selection, Prospective Studies, Prosthesis Design, Registries, Retrospective Studies, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome",
author = "Jens Wiebe and Jennifer Franke and Edith Lubos and Peter Boekstegers and Wolfgang Schillinger and Taoufik Ouarrak and May, {Andreas E} and Holger Eggebrecht and Karl-Heinz Kuck and Stephan Baldus and Jochen Senges and Horst Sievert and {German Transcatheter Mitral Valve Intervention (TRAMI) investigators}",
note = "{\textcopyright} 2014 Wiley Periodicals, Inc.",
year = "2014",
month = oct,
day = "1",
doi = "10.1002/ccd.25493",
language = "English",
volume = "84",
pages = "591--598",
journal = "CATHETER CARDIO INTE",
issn = "1522-1946",
publisher = "Wiley-Liss Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - Percutaneous mitral valve repair with the MitraClip system according to the predicted risk by the logistic EuroSCORE: preliminary results from the German Transcatheter Mitral Valve Interventions (TRAMI) Registry

AU - Wiebe, Jens

AU - Franke, Jennifer

AU - Lubos, Edith

AU - Boekstegers, Peter

AU - Schillinger, Wolfgang

AU - Ouarrak, Taoufik

AU - May, Andreas E

AU - Eggebrecht, Holger

AU - Kuck, Karl-Heinz

AU - Baldus, Stephan

AU - Senges, Jochen

AU - Sievert, Horst

AU - German Transcatheter Mitral Valve Intervention (TRAMI) investigators

N1 - © 2014 Wiley Periodicals, Inc.

PY - 2014/10/1

Y1 - 2014/10/1

N2 - OBJECTIVE: To evaluate in-hospital and short-term outcomes of percutaneous mitral valve repair according to patients' logistic EuroSCORE (logEuroSCORE) in a multicenter registryBACKGROUND: The logEuroSCORE is an established tool to predict the risk of mortality during cardiac surgery. In high-risk patients percutaneous mitral valve repair with the MitraClip system represents a less-invasive alternativeMETHODS: Data from 1002 patients, who underwent percutaneous mitral valve repair with the MitraClip system, were analyzed in the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. A logEuroSCORE (mortality risk in %) ≥ 20 was considered high riskRESULTS: Of all patients, 557 (55.6%) had a logEuroSCORE ≥ 20. Implantation of the MitraClip was successful in 95.5 % (942/986) patients. Moderate residual mitral valve regurgitation was more often detected in patients with a logEuroSCORE ≥ 20 (23.8% vs. 17.1%, respectively, P < 0.05). In patients with a logEuroSCORE ≥ 20 the procedural complication rate was 8.9% (vs. 6.4, n.s.) and the in-hospital MACCE rate 4.9% (vs. 1.4% P < 0.01). The in-hospital mortality rate in patients with a logEuroSCORE ≥ 20 and logEuroSCORE < 20 was 4.3 and 1.1%, respectively (P ≤ 0.01) CONCLUSION: Percutaneous mitral valve repair with the MitraClip system is feasible in patients with a logEuroSCORE ≥ 20 with similar procedural results compared to patients with lower predicted risk. Although mortality was four times higher than in patients with logEuroSCORE < 20, mortality in high risk patients was lower than predicted. In those with a logEuroSCORE ≥ 20, moderate residual mitral valve regurgitation was more frequent.

AB - OBJECTIVE: To evaluate in-hospital and short-term outcomes of percutaneous mitral valve repair according to patients' logistic EuroSCORE (logEuroSCORE) in a multicenter registryBACKGROUND: The logEuroSCORE is an established tool to predict the risk of mortality during cardiac surgery. In high-risk patients percutaneous mitral valve repair with the MitraClip system represents a less-invasive alternativeMETHODS: Data from 1002 patients, who underwent percutaneous mitral valve repair with the MitraClip system, were analyzed in the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. A logEuroSCORE (mortality risk in %) ≥ 20 was considered high riskRESULTS: Of all patients, 557 (55.6%) had a logEuroSCORE ≥ 20. Implantation of the MitraClip was successful in 95.5 % (942/986) patients. Moderate residual mitral valve regurgitation was more often detected in patients with a logEuroSCORE ≥ 20 (23.8% vs. 17.1%, respectively, P < 0.05). In patients with a logEuroSCORE ≥ 20 the procedural complication rate was 8.9% (vs. 6.4, n.s.) and the in-hospital MACCE rate 4.9% (vs. 1.4% P < 0.01). The in-hospital mortality rate in patients with a logEuroSCORE ≥ 20 and logEuroSCORE < 20 was 4.3 and 1.1%, respectively (P ≤ 0.01) CONCLUSION: Percutaneous mitral valve repair with the MitraClip system is feasible in patients with a logEuroSCORE ≥ 20 with similar procedural results compared to patients with lower predicted risk. Although mortality was four times higher than in patients with logEuroSCORE < 20, mortality in high risk patients was lower than predicted. In those with a logEuroSCORE ≥ 20, moderate residual mitral valve regurgitation was more frequent.

KW - Aged

KW - Aged, 80 and over

KW - Cardiac Catheterization/adverse effects

KW - Chi-Square Distribution

KW - Feasibility Studies

KW - Female

KW - Germany

KW - Heart Valve Prosthesis

KW - Heart Valve Prosthesis Implantation/adverse effects

KW - Hospital Mortality

KW - Humans

KW - Logistic Models

KW - Male

KW - Mitral Valve/physiopathology

KW - Mitral Valve Insufficiency/diagnosis

KW - Patient Selection

KW - Prospective Studies

KW - Prosthesis Design

KW - Registries

KW - Retrospective Studies

KW - Risk Assessment

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1002/ccd.25493

DO - 10.1002/ccd.25493

M3 - SCORING: Journal article

C2 - 24664460

VL - 84

SP - 591

EP - 598

JO - CATHETER CARDIO INTE

JF - CATHETER CARDIO INTE

SN - 1522-1946

IS - 4

ER -