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Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018

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Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018. / Olschewski, Andrea; Berghausen, Eva M; Eichstaedt, Christina A; Fleischmann, Bernd K; Grünig, Ekkehard; Grünig, Gabriele; Hansmann, Georg; Harbaum, Lars; Hennigs, Jan K; Jonigk, Danny; Kuebler, Wolfgang M; Kwapiszewska, Grazyna; Pullamsetti, Soni S; Stacher, Elvira; Weissmann, Norbert; Wenzel, Daniela; Schermuly, Ralph T.

In: INT J CARDIOL, Vol. 272S, No. S1, 01.12.2018, p. 4-10.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Olschewski, A, Berghausen, EM, Eichstaedt, CA, Fleischmann, BK, Grünig, E, Grünig, G, Hansmann, G, Harbaum, L, Hennigs, JK, Jonigk, D, Kuebler, WM, Kwapiszewska, G, Pullamsetti, SS, Stacher, E, Weissmann, N, Wenzel, D & Schermuly, RT 2018, 'Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018', INT J CARDIOL, vol. 272S, no. S1, pp. 4-10. https://doi.org/10.1016/j.ijcard.2018.09.070

APA

Olschewski, A., Berghausen, E. M., Eichstaedt, C. A., Fleischmann, B. K., Grünig, E., Grünig, G., Hansmann, G., Harbaum, L., Hennigs, J. K., Jonigk, D., Kuebler, W. M., Kwapiszewska, G., Pullamsetti, S. S., Stacher, E., Weissmann, N., Wenzel, D., & Schermuly, R. T. (2018). Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018. INT J CARDIOL, 272S(S1), 4-10. https://doi.org/10.1016/j.ijcard.2018.09.070

Vancouver

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G et al. Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018. INT J CARDIOL. 2018 Dec 1;272S(S1):4-10. https://doi.org/10.1016/j.ijcard.2018.09.070

Bibtex

@article{3cf4b8c436ae447f838052ce48ed6764,
title = "Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018",
abstract = "The European guidelines, which focus on clinical aspects of pulmonary hypertension (PH), provide only minimal information about the pathophysiological concepts of PH. Here, we review this topic in greater detail, focusing on specific aspects in the pathobiology, pathology and genetics, which include mechanisms of vascular inflammation, the role of transcription factors, ion channels/ion channel diseases, hypoxic pulmonary vasoconstriction, genetics/epigenetics, metabolic dysfunction, and the potential future role of histopathology of PH in the modern era of PH therapy. In addition to new insights in the pathobiology of this disease, this working group of the Cologne Consensus Conference also highlights novel concepts and potential new therapeutic targets to further improve the treatment options in PAH.",
keywords = "Journal Article",
author = "Andrea Olschewski and Berghausen, {Eva M} and Eichstaedt, {Christina A} and Fleischmann, {Bernd K} and Ekkehard Gr{\"u}nig and Gabriele Gr{\"u}nig and Georg Hansmann and Lars Harbaum and Hennigs, {Jan K} and Danny Jonigk and Kuebler, {Wolfgang M} and Grazyna Kwapiszewska and Pullamsetti, {Soni S} and Elvira Stacher and Norbert Weissmann and Daniela Wenzel and Schermuly, {Ralph T}",
note = "Copyright {\textcopyright} 2018. Published by Elsevier B.V.",
year = "2018",
month = dec,
day = "1",
doi = "10.1016/j.ijcard.2018.09.070",
language = "English",
volume = "272S",
pages = "4--10",
journal = "INT J CARDIOL",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",
number = "S1",

}

RIS

TY - JOUR

T1 - Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018

AU - Olschewski, Andrea

AU - Berghausen, Eva M

AU - Eichstaedt, Christina A

AU - Fleischmann, Bernd K

AU - Grünig, Ekkehard

AU - Grünig, Gabriele

AU - Hansmann, Georg

AU - Harbaum, Lars

AU - Hennigs, Jan K

AU - Jonigk, Danny

AU - Kuebler, Wolfgang M

AU - Kwapiszewska, Grazyna

AU - Pullamsetti, Soni S

AU - Stacher, Elvira

AU - Weissmann, Norbert

AU - Wenzel, Daniela

AU - Schermuly, Ralph T

N1 - Copyright © 2018. Published by Elsevier B.V.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - The European guidelines, which focus on clinical aspects of pulmonary hypertension (PH), provide only minimal information about the pathophysiological concepts of PH. Here, we review this topic in greater detail, focusing on specific aspects in the pathobiology, pathology and genetics, which include mechanisms of vascular inflammation, the role of transcription factors, ion channels/ion channel diseases, hypoxic pulmonary vasoconstriction, genetics/epigenetics, metabolic dysfunction, and the potential future role of histopathology of PH in the modern era of PH therapy. In addition to new insights in the pathobiology of this disease, this working group of the Cologne Consensus Conference also highlights novel concepts and potential new therapeutic targets to further improve the treatment options in PAH.

AB - The European guidelines, which focus on clinical aspects of pulmonary hypertension (PH), provide only minimal information about the pathophysiological concepts of PH. Here, we review this topic in greater detail, focusing on specific aspects in the pathobiology, pathology and genetics, which include mechanisms of vascular inflammation, the role of transcription factors, ion channels/ion channel diseases, hypoxic pulmonary vasoconstriction, genetics/epigenetics, metabolic dysfunction, and the potential future role of histopathology of PH in the modern era of PH therapy. In addition to new insights in the pathobiology of this disease, this working group of the Cologne Consensus Conference also highlights novel concepts and potential new therapeutic targets to further improve the treatment options in PAH.

KW - Journal Article

U2 - 10.1016/j.ijcard.2018.09.070

DO - 10.1016/j.ijcard.2018.09.070

M3 - SCORING: Review article

C2 - 30314839

VL - 272S

SP - 4

EP - 10

JO - INT J CARDIOL

JF - INT J CARDIOL

SN - 0167-5273

IS - S1

ER -