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P53 auto-antibodies in the sera of patients with oral squamous cell carcinoma

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P53 auto-antibodies in the sera of patients with oral squamous cell carcinoma. / Friedrich, R E; Bartel-Friedrich, S; Plambeck, K; Bahlo, M; Klapdor, R.

In: ANTICANCER RES, Vol. 17, No. 4B, 1997, p. 3183-4.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Friedrich, RE, Bartel-Friedrich, S, Plambeck, K, Bahlo, M & Klapdor, R 1997, 'P53 auto-antibodies in the sera of patients with oral squamous cell carcinoma', ANTICANCER RES, vol. 17, no. 4B, pp. 3183-4.

APA

Friedrich, R. E., Bartel-Friedrich, S., Plambeck, K., Bahlo, M., & Klapdor, R. (1997). P53 auto-antibodies in the sera of patients with oral squamous cell carcinoma. ANTICANCER RES, 17(4B), 3183-4.

Vancouver

Friedrich RE, Bartel-Friedrich S, Plambeck K, Bahlo M, Klapdor R. P53 auto-antibodies in the sera of patients with oral squamous cell carcinoma. ANTICANCER RES. 1997;17(4B):3183-4.

Bibtex

@article{08280b269ade47ccb9669297df03c64c,
title = "P53 auto-antibodies in the sera of patients with oral squamous cell carcinoma",
abstract = "AIM: To investigate the sera of patients with oral squamous cell carcinoma (OSCC) for the existence of p53 auto-antibodies.MATERIAL AND METHODS: The sera of thirty-nine OSCC-patients were investigated. All samples were from untreated patients with no history of another neoplastic disease. The sera of nine healthy subjects served as controls.RESULTS: P53 auto-antibodies were not detected both in all healthy subjects and in 20.6% OSCC-patients with their disease at an advanced stage. We prove that the extinction rates for p53 auto-antibodies in OSCC are very weak in the majority of investigated sera (50%) and are not related to tumour stage.CONCLUSION: It is unlikely that p53 auto-antibodies can serve as a prognostic marker of OSCC.",
keywords = "Autoantibodies, Carcinoma, Squamous Cell, Humans, Mouth Neoplasms, Prognosis, Tumor Suppressor Protein p53",
author = "Friedrich, {R E} and S Bartel-Friedrich and K Plambeck and M Bahlo and R Klapdor",
year = "1997",
language = "English",
volume = "17",
pages = "3183--4",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "4B",

}

RIS

TY - JOUR

T1 - P53 auto-antibodies in the sera of patients with oral squamous cell carcinoma

AU - Friedrich, R E

AU - Bartel-Friedrich, S

AU - Plambeck, K

AU - Bahlo, M

AU - Klapdor, R

PY - 1997

Y1 - 1997

N2 - AIM: To investigate the sera of patients with oral squamous cell carcinoma (OSCC) for the existence of p53 auto-antibodies.MATERIAL AND METHODS: The sera of thirty-nine OSCC-patients were investigated. All samples were from untreated patients with no history of another neoplastic disease. The sera of nine healthy subjects served as controls.RESULTS: P53 auto-antibodies were not detected both in all healthy subjects and in 20.6% OSCC-patients with their disease at an advanced stage. We prove that the extinction rates for p53 auto-antibodies in OSCC are very weak in the majority of investigated sera (50%) and are not related to tumour stage.CONCLUSION: It is unlikely that p53 auto-antibodies can serve as a prognostic marker of OSCC.

AB - AIM: To investigate the sera of patients with oral squamous cell carcinoma (OSCC) for the existence of p53 auto-antibodies.MATERIAL AND METHODS: The sera of thirty-nine OSCC-patients were investigated. All samples were from untreated patients with no history of another neoplastic disease. The sera of nine healthy subjects served as controls.RESULTS: P53 auto-antibodies were not detected both in all healthy subjects and in 20.6% OSCC-patients with their disease at an advanced stage. We prove that the extinction rates for p53 auto-antibodies in OSCC are very weak in the majority of investigated sera (50%) and are not related to tumour stage.CONCLUSION: It is unlikely that p53 auto-antibodies can serve as a prognostic marker of OSCC.

KW - Autoantibodies

KW - Carcinoma, Squamous Cell

KW - Humans

KW - Mouth Neoplasms

KW - Prognosis

KW - Tumor Suppressor Protein p53

M3 - SCORING: Journal article

C2 - 9329632

VL - 17

SP - 3183

EP - 3184

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 4B

ER -