Research ExplorerPublicationsP50, N100, and P200 Sensory Gating in Panic Disorder

P50, N100, and P200 Sensory Gating in Panic Disorder

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P50, N100, and P200 Sensory Gating in Panic Disorder. / Thoma, Lars; Rentzsch, Johannes; Gaudlitz, Katharina; Tänzer, Nicole; Gallinat, Jürgen; Kathmann, Norbert; Ströhle, Andreas; Plag, Jens.

In: CLIN EEG NEUROSCI, Vol. 51, No. 5, 09.2020, p. 317-324.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Thoma, L, Rentzsch, J, Gaudlitz, K, Tänzer, N, Gallinat, J, Kathmann, N, Ströhle, A & Plag, J 2020, 'P50, N100, and P200 Sensory Gating in Panic Disorder', CLIN EEG NEUROSCI, vol. 51, no. 5, pp. 317-324. https://doi.org/10.1177/1550059419899324

APA

Thoma, L., Rentzsch, J., Gaudlitz, K., Tänzer, N., Gallinat, J., Kathmann, N., Ströhle, A., & Plag, J. (2020). P50, N100, and P200 Sensory Gating in Panic Disorder. CLIN EEG NEUROSCI, 51(5), 317-324. https://doi.org/10.1177/1550059419899324

Vancouver

Thoma L, Rentzsch J, Gaudlitz K, Tänzer N, Gallinat J, Kathmann N et al. P50, N100, and P200 Sensory Gating in Panic Disorder. CLIN EEG NEUROSCI. 2020 Sep;51(5):317-324. https://doi.org/10.1177/1550059419899324

Bibtex

@article{146ba61a5b0840b18b31ee1aaba20822,
title = "P50, N100, and P200 Sensory Gating in Panic Disorder",
abstract = "Panic disorder (PD) has been linked to abnormalities in information processing. However, only little evidence has been published for sensory gating in PD. Sensory gating describes the brain's ability to exclude stimuli of low relevance from higher level information processing, thereby sustaining efficient cognitive processing. Deficits in sensory gating have been associated with various psychiatric conditions, most prominently schizophrenia. In this case-control event-related potential study, we tested 32 patients with PD and 39 healthy controls in a double click paradigm. Both groups were compared with regard to pre-attentive (P50), early-attentive (N100), and late-attentive (P200) sensory gating indices. Contrary to a hypothesized deficit, PD patients and healthy controls showed no differences in P50, N100 and P200 values. These results suggest that sensory gating seems to be functional across the pre-attentive, early-attentive, and late-attentive time span in this clinical population. Given this consistency across auditory sensory gating indices, further research aiming to clarify information processing deficits in PD should focus on other neurophysiological markers to investigate information processing deficits in PD (eg, P300, error-related negativity or mismatch negativity).",
author = "Lars Thoma and Johannes Rentzsch and Katharina Gaudlitz and Nicole T{\"a}nzer and J{\"u}rgen Gallinat and Norbert Kathmann and Andreas Str{\"o}hle and Jens Plag",
year = "2020",
month = sep,
doi = "10.1177/1550059419899324",
language = "English",
volume = "51",
pages = "317--324",
journal = "CLIN EEG NEUROSCI",
issn = "1550-0594",
publisher = "EEG and Clinical Neuroscience Society (ECNS)",
number = "5",

}

RIS

TY - JOUR

T1 - P50, N100, and P200 Sensory Gating in Panic Disorder

AU - Thoma, Lars

AU - Rentzsch, Johannes

AU - Gaudlitz, Katharina

AU - Tänzer, Nicole

AU - Gallinat, Jürgen

AU - Kathmann, Norbert

AU - Ströhle, Andreas

AU - Plag, Jens

PY - 2020/9

Y1 - 2020/9

N2 - Panic disorder (PD) has been linked to abnormalities in information processing. However, only little evidence has been published for sensory gating in PD. Sensory gating describes the brain's ability to exclude stimuli of low relevance from higher level information processing, thereby sustaining efficient cognitive processing. Deficits in sensory gating have been associated with various psychiatric conditions, most prominently schizophrenia. In this case-control event-related potential study, we tested 32 patients with PD and 39 healthy controls in a double click paradigm. Both groups were compared with regard to pre-attentive (P50), early-attentive (N100), and late-attentive (P200) sensory gating indices. Contrary to a hypothesized deficit, PD patients and healthy controls showed no differences in P50, N100 and P200 values. These results suggest that sensory gating seems to be functional across the pre-attentive, early-attentive, and late-attentive time span in this clinical population. Given this consistency across auditory sensory gating indices, further research aiming to clarify information processing deficits in PD should focus on other neurophysiological markers to investigate information processing deficits in PD (eg, P300, error-related negativity or mismatch negativity).

AB - Panic disorder (PD) has been linked to abnormalities in information processing. However, only little evidence has been published for sensory gating in PD. Sensory gating describes the brain's ability to exclude stimuli of low relevance from higher level information processing, thereby sustaining efficient cognitive processing. Deficits in sensory gating have been associated with various psychiatric conditions, most prominently schizophrenia. In this case-control event-related potential study, we tested 32 patients with PD and 39 healthy controls in a double click paradigm. Both groups were compared with regard to pre-attentive (P50), early-attentive (N100), and late-attentive (P200) sensory gating indices. Contrary to a hypothesized deficit, PD patients and healthy controls showed no differences in P50, N100 and P200 values. These results suggest that sensory gating seems to be functional across the pre-attentive, early-attentive, and late-attentive time span in this clinical population. Given this consistency across auditory sensory gating indices, further research aiming to clarify information processing deficits in PD should focus on other neurophysiological markers to investigate information processing deficits in PD (eg, P300, error-related negativity or mismatch negativity).

U2 - 10.1177/1550059419899324

DO - 10.1177/1550059419899324

M3 - SCORING: Journal article

C2 - 31914806

VL - 51

SP - 317

EP - 324

JO - CLIN EEG NEUROSCI

JF - CLIN EEG NEUROSCI

SN - 1550-0594

IS - 5

ER -