Research ExplorerPublicationsOxygen inhalation has no effect on provoked cranial autonomi...

Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers

Standard

Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers. / Schroeder, Celina F; Basedau, Hauke; May, Arne; Möller, Maike.

In: CEPHALALGIA, Vol. 43, No. 4, 04.2023, p. 3331024231161269.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schroeder, CF, Basedau, H, May, A & Möller, M 2023, 'Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers', CEPHALALGIA, vol. 43, no. 4, pp. 3331024231161269. https://doi.org/10.1177/03331024231161269

APA

Schroeder, C. F., Basedau, H., May, A., & Möller, M. (2023). Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers. CEPHALALGIA, 43(4), 3331024231161269. https://doi.org/10.1177/03331024231161269

Vancouver

Schroeder CF, Basedau H, May A, Möller M. Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers. CEPHALALGIA. 2023 Apr;43(4):3331024231161269. https://doi.org/10.1177/03331024231161269

Bibtex

@article{881d5f0459a140dca84259007784032e,
title = "Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers",
abstract = "ObjectiveInhalation of oxygen is highly effective in cluster headache, a subtype of trigeminal autonomic cephalgias. Since oxygen has no effect on nociceptive pain, the mechanism of action is still unknown. The present study investigated whether oxygen inhalation modifies the trigeminal autonomic reflex arc in healthy volunteers.Methods21 healthy volunteers participated in a randomized, placebo controlled, double-blind, cross-over, and within-subject study design. In a randomized order demand valve inhalation of 100% oxygen or medical air were administered. Capillary blood samples were collected to control for blood gas changes. Cranial parasympathetic output (lacrimation) was provoked using kinetic oscillation stimulation of the nasal mucosa. Standardized measurement of lacrimation between baseline and kinetic oscillation stimulation served as a measure of induced cranial autonomic output.ResultsThere was no significant difference in parasympathetic output after oxygen inhalation when compared to inhalation of medical air.ConclusionThe inhalation of 100% oxygen does not affect the parasympathetic reflex arc of the trigeminal autonomic reflex.",
author = "Schroeder, {Celina F} and Hauke Basedau and Arne May and Maike M{\"o}ller",
year = "2023",
month = apr,
doi = "10.1177/03331024231161269",
language = "English",
volume = "43",
pages = "3331024231161269",
journal = "CEPHALALGIA",
issn = "0333-1024",
publisher = "SAGE Publications",
number = "4",

}

RIS

TY - JOUR

T1 - Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers

AU - Schroeder, Celina F

AU - Basedau, Hauke

AU - May, Arne

AU - Möller, Maike

PY - 2023/4

Y1 - 2023/4

N2 - ObjectiveInhalation of oxygen is highly effective in cluster headache, a subtype of trigeminal autonomic cephalgias. Since oxygen has no effect on nociceptive pain, the mechanism of action is still unknown. The present study investigated whether oxygen inhalation modifies the trigeminal autonomic reflex arc in healthy volunteers.Methods21 healthy volunteers participated in a randomized, placebo controlled, double-blind, cross-over, and within-subject study design. In a randomized order demand valve inhalation of 100% oxygen or medical air were administered. Capillary blood samples were collected to control for blood gas changes. Cranial parasympathetic output (lacrimation) was provoked using kinetic oscillation stimulation of the nasal mucosa. Standardized measurement of lacrimation between baseline and kinetic oscillation stimulation served as a measure of induced cranial autonomic output.ResultsThere was no significant difference in parasympathetic output after oxygen inhalation when compared to inhalation of medical air.ConclusionThe inhalation of 100% oxygen does not affect the parasympathetic reflex arc of the trigeminal autonomic reflex.

AB - ObjectiveInhalation of oxygen is highly effective in cluster headache, a subtype of trigeminal autonomic cephalgias. Since oxygen has no effect on nociceptive pain, the mechanism of action is still unknown. The present study investigated whether oxygen inhalation modifies the trigeminal autonomic reflex arc in healthy volunteers.Methods21 healthy volunteers participated in a randomized, placebo controlled, double-blind, cross-over, and within-subject study design. In a randomized order demand valve inhalation of 100% oxygen or medical air were administered. Capillary blood samples were collected to control for blood gas changes. Cranial parasympathetic output (lacrimation) was provoked using kinetic oscillation stimulation of the nasal mucosa. Standardized measurement of lacrimation between baseline and kinetic oscillation stimulation served as a measure of induced cranial autonomic output.ResultsThere was no significant difference in parasympathetic output after oxygen inhalation when compared to inhalation of medical air.ConclusionThe inhalation of 100% oxygen does not affect the parasympathetic reflex arc of the trigeminal autonomic reflex.

U2 - 10.1177/03331024231161269

DO - 10.1177/03331024231161269

M3 - SCORING: Journal article

C2 - 36918826

VL - 43

SP - 3331024231161269

JO - CEPHALALGIA

JF - CEPHALALGIA

SN - 0333-1024

IS - 4

ER -