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Ovarian cancer: diagnosis and treatment

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Ovarian cancer: diagnosis and treatment. / Burges, Alexander; Schmalfeldt, Barbara.

In: DTSCH ARZTEBL INT, Vol. 108, No. 38, 09.2011, p. 635-41.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Burges, A & Schmalfeldt, B 2011, 'Ovarian cancer: diagnosis and treatment', DTSCH ARZTEBL INT, vol. 108, no. 38, pp. 635-41. https://doi.org/10.3238/arztebl.2011.0635

APA

Burges, A., & Schmalfeldt, B. (2011). Ovarian cancer: diagnosis and treatment. DTSCH ARZTEBL INT, 108(38), 635-41. https://doi.org/10.3238/arztebl.2011.0635

Vancouver

Burges A, Schmalfeldt B. Ovarian cancer: diagnosis and treatment. DTSCH ARZTEBL INT. 2011 Sep;108(38):635-41. https://doi.org/10.3238/arztebl.2011.0635

Bibtex

@article{f9e4b25c69eb4d34b88d20aa8ad8a5fb,
title = "Ovarian cancer: diagnosis and treatment",
abstract = "BACKGROUND: Patients with ovarian cancer usually present to a family physician with nonspecific symptoms, most often abdominal pain. The outcome depends above all on the stage of the disease when it is diagnosed and on the quality of treatment.METHODS: This article is based on a review of selected publications from 2000 to 2010 that were retrieved by an automated search in Medline on the terms {"}ovarian cancer,{"} {"}screening,{"} {"}diagnosis,{"} {"}treatment,{"} and {"}prognosis,{"} as well as the interdisciplinary S2k guideline Diagnostik und Therapie maligner Ovarialtumoren (the diagnosis and treatment of malignant ovarian tumors) issued in 2007 by the Ovarian Tumor Committee of the German Consortium of Gynecologic Oncology (AGO) and the Committee's updated recommendations of 2009.RESULTS: The proper treatment of early ovarian cancer involves resection of the primary tumor and all macroscopically visible tumor mass as well as meticulous inspection of the entire abdominal cavity for staging. Platinum-based chemotherapy is indicated for women with ovarian cancer in FIGO stage I to IIA (except stage IA, G1). For women with advanced ovarian cancer, the prognosis largely depends on the extent of tumor mass reduction on initial surgery. Complete resection confers significantly longer survival (median 5 years) than incomplete resection. After surgery, the standard adjuvant chemotherapy consists of a combination of carboplatin and paclitaxel. Treatment that conforms to published guidelines significantly improves survival (60% versus 25% at 3 years).CONCLUSION: The possibility of ovarian cancer must be considered for any woman who presents with new, persistent, nonspecific abdominal pain. Ovarian cancer should always be treated in accordance with published guidelines.",
keywords = "Adenocarcinoma, Combined Modality Therapy, Cooperative Behavior, Diaphragm, Disease Progression, Early Diagnosis, Female, Germany, Guideline Adherence, Humans, Interdisciplinary Communication, Mass Screening, Middle Aged, Neoplasm Invasiveness, Neoplasm Staging, Omentum, Ovarian Neoplasms, Peritoneal Neoplasms, Prognosis",
author = "Alexander Burges and Barbara Schmalfeldt",
year = "2011",
month = sep,
doi = "10.3238/arztebl.2011.0635",
language = "English",
volume = "108",
pages = "635--41",
journal = "DTSCH ARZTEBL INT",
issn = "1866-0452",
publisher = "Deutscher Arzte-Verlag",
number = "38",

}

RIS

TY - JOUR

T1 - Ovarian cancer: diagnosis and treatment

AU - Burges, Alexander

AU - Schmalfeldt, Barbara

PY - 2011/9

Y1 - 2011/9

N2 - BACKGROUND: Patients with ovarian cancer usually present to a family physician with nonspecific symptoms, most often abdominal pain. The outcome depends above all on the stage of the disease when it is diagnosed and on the quality of treatment.METHODS: This article is based on a review of selected publications from 2000 to 2010 that were retrieved by an automated search in Medline on the terms "ovarian cancer," "screening," "diagnosis," "treatment," and "prognosis," as well as the interdisciplinary S2k guideline Diagnostik und Therapie maligner Ovarialtumoren (the diagnosis and treatment of malignant ovarian tumors) issued in 2007 by the Ovarian Tumor Committee of the German Consortium of Gynecologic Oncology (AGO) and the Committee's updated recommendations of 2009.RESULTS: The proper treatment of early ovarian cancer involves resection of the primary tumor and all macroscopically visible tumor mass as well as meticulous inspection of the entire abdominal cavity for staging. Platinum-based chemotherapy is indicated for women with ovarian cancer in FIGO stage I to IIA (except stage IA, G1). For women with advanced ovarian cancer, the prognosis largely depends on the extent of tumor mass reduction on initial surgery. Complete resection confers significantly longer survival (median 5 years) than incomplete resection. After surgery, the standard adjuvant chemotherapy consists of a combination of carboplatin and paclitaxel. Treatment that conforms to published guidelines significantly improves survival (60% versus 25% at 3 years).CONCLUSION: The possibility of ovarian cancer must be considered for any woman who presents with new, persistent, nonspecific abdominal pain. Ovarian cancer should always be treated in accordance with published guidelines.

AB - BACKGROUND: Patients with ovarian cancer usually present to a family physician with nonspecific symptoms, most often abdominal pain. The outcome depends above all on the stage of the disease when it is diagnosed and on the quality of treatment.METHODS: This article is based on a review of selected publications from 2000 to 2010 that were retrieved by an automated search in Medline on the terms "ovarian cancer," "screening," "diagnosis," "treatment," and "prognosis," as well as the interdisciplinary S2k guideline Diagnostik und Therapie maligner Ovarialtumoren (the diagnosis and treatment of malignant ovarian tumors) issued in 2007 by the Ovarian Tumor Committee of the German Consortium of Gynecologic Oncology (AGO) and the Committee's updated recommendations of 2009.RESULTS: The proper treatment of early ovarian cancer involves resection of the primary tumor and all macroscopically visible tumor mass as well as meticulous inspection of the entire abdominal cavity for staging. Platinum-based chemotherapy is indicated for women with ovarian cancer in FIGO stage I to IIA (except stage IA, G1). For women with advanced ovarian cancer, the prognosis largely depends on the extent of tumor mass reduction on initial surgery. Complete resection confers significantly longer survival (median 5 years) than incomplete resection. After surgery, the standard adjuvant chemotherapy consists of a combination of carboplatin and paclitaxel. Treatment that conforms to published guidelines significantly improves survival (60% versus 25% at 3 years).CONCLUSION: The possibility of ovarian cancer must be considered for any woman who presents with new, persistent, nonspecific abdominal pain. Ovarian cancer should always be treated in accordance with published guidelines.

KW - Adenocarcinoma

KW - Combined Modality Therapy

KW - Cooperative Behavior

KW - Diaphragm

KW - Disease Progression

KW - Early Diagnosis

KW - Female

KW - Germany

KW - Guideline Adherence

KW - Humans

KW - Interdisciplinary Communication

KW - Mass Screening

KW - Middle Aged

KW - Neoplasm Invasiveness

KW - Neoplasm Staging

KW - Omentum

KW - Ovarian Neoplasms

KW - Peritoneal Neoplasms

KW - Prognosis

U2 - 10.3238/arztebl.2011.0635

DO - 10.3238/arztebl.2011.0635

M3 - SCORING: Journal article

C2 - 22025930

VL - 108

SP - 635

EP - 641

JO - DTSCH ARZTEBL INT

JF - DTSCH ARZTEBL INT

SN - 1866-0452

IS - 38

ER -