Outcome after Posterior Vertebral Column Resection in Patients with Severe Osteoporotic Fractures - A Retrospective Analysis from Two Centers

Standard

Outcome after Posterior Vertebral Column Resection in Patients with Severe Osteoporotic Fractures - A Retrospective Analysis from Two Centers. / Koepke, L.-G.; Weiser, Lukas; Stangenberg, Martin; Dreimann, Marc; Heuer, Annika; Strahl, André; Viezens, Lennart.

In: MEDICINA-LITHUANIA, Vol. 58, No. 2, 277, 12.02.2022.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

APA

Vancouver

Bibtex

@article{4a23d7f5862d4ab8b6a44c574df1b605,
title = "Outcome after Posterior Vertebral Column Resection in Patients with Severe Osteoporotic Fractures - A Retrospective Analysis from Two Centers",
abstract = "Background and Objectives: In osteoporotic fractures of the spine with resulting kyphosis and threatening compression of neural structures, therapeutic decisions are difficult. The posterior vertebral column resection (pVCR) has been described by different authors as a surgical treatment in a single-stage posterior procedure. The aim of this study is to evaluate midterm outcomes of patients treated by pVCR due to severe osteoporotic fractures. Materials and Methods: Retrospective data analysis of all the patients treated for osteoporotic fractures by pVCR from 2012-2020 at two centers was performed. Demographic data, visual analog scale (VAS), Frankel scale (FS), Karnofsky performance status (KPS), radiological result and spinal fusion rates were evaluated. Results: A total of 17 patients were included. The mean age was 70 ± 10.2 y. The mean VAS decreased significantly from 7.7 ± 2.8 preoperatively to 3.0 ± 1.6 at last follow-up (p < 0.001) and the segmental kyphosis decreased from 29.4 ± 14.1° to 7.9 ± 8.0° (p < 0.001). The neurologic function on the FS did not worsen in any and improved in four of the patients. The median KPS remained stable over the whole observation period (70% vs. 70%). Spinal fusion was observed in nine out of nine patients who received CT follow-up >120 days after index surgery. Conclusions: This study showed that pVCR is a safe surgical technique with few surgical complications and no neurological deterioration considering the cohort. The patients' segmental kyphosis and VAS improved significantly, while the KPS remained stable.",
keywords = "Aged, Aged, 80 and over, Humans, Kyphosis/etiology, Lumbar Vertebrae/surgery, Middle Aged, Osteoporotic Fractures/surgery, Retrospective Studies, Spinal Fractures/surgery, Spinal Fusion, Spine/surgery, Thoracic Vertebrae/surgery, Treatment Outcome",
author = "L.-G. Koepke and Lukas Weiser and Martin Stangenberg and Marc Dreimann and Annika Heuer and Andr{\'e} Strahl and Lennart Viezens",
year = "2022",
month = feb,
day = "12",
doi = "10.3390/medicina58020277",
language = "English",
volume = "58",
journal = "MEDICINA-LITHUANIA",
issn = "1010-660X",
publisher = "Kauno Medicinos Universitetas",
number = "2",

}

RIS

TY - JOUR

T1 - Outcome after Posterior Vertebral Column Resection in Patients with Severe Osteoporotic Fractures - A Retrospective Analysis from Two Centers

AU - Koepke, L.-G.

AU - Weiser, Lukas

AU - Stangenberg, Martin

AU - Dreimann, Marc

AU - Heuer, Annika

AU - Strahl, André

AU - Viezens, Lennart

PY - 2022/2/12

Y1 - 2022/2/12

N2 - Background and Objectives: In osteoporotic fractures of the spine with resulting kyphosis and threatening compression of neural structures, therapeutic decisions are difficult. The posterior vertebral column resection (pVCR) has been described by different authors as a surgical treatment in a single-stage posterior procedure. The aim of this study is to evaluate midterm outcomes of patients treated by pVCR due to severe osteoporotic fractures. Materials and Methods: Retrospective data analysis of all the patients treated for osteoporotic fractures by pVCR from 2012-2020 at two centers was performed. Demographic data, visual analog scale (VAS), Frankel scale (FS), Karnofsky performance status (KPS), radiological result and spinal fusion rates were evaluated. Results: A total of 17 patients were included. The mean age was 70 ± 10.2 y. The mean VAS decreased significantly from 7.7 ± 2.8 preoperatively to 3.0 ± 1.6 at last follow-up (p < 0.001) and the segmental kyphosis decreased from 29.4 ± 14.1° to 7.9 ± 8.0° (p < 0.001). The neurologic function on the FS did not worsen in any and improved in four of the patients. The median KPS remained stable over the whole observation period (70% vs. 70%). Spinal fusion was observed in nine out of nine patients who received CT follow-up >120 days after index surgery. Conclusions: This study showed that pVCR is a safe surgical technique with few surgical complications and no neurological deterioration considering the cohort. The patients' segmental kyphosis and VAS improved significantly, while the KPS remained stable.

AB - Background and Objectives: In osteoporotic fractures of the spine with resulting kyphosis and threatening compression of neural structures, therapeutic decisions are difficult. The posterior vertebral column resection (pVCR) has been described by different authors as a surgical treatment in a single-stage posterior procedure. The aim of this study is to evaluate midterm outcomes of patients treated by pVCR due to severe osteoporotic fractures. Materials and Methods: Retrospective data analysis of all the patients treated for osteoporotic fractures by pVCR from 2012-2020 at two centers was performed. Demographic data, visual analog scale (VAS), Frankel scale (FS), Karnofsky performance status (KPS), radiological result and spinal fusion rates were evaluated. Results: A total of 17 patients were included. The mean age was 70 ± 10.2 y. The mean VAS decreased significantly from 7.7 ± 2.8 preoperatively to 3.0 ± 1.6 at last follow-up (p < 0.001) and the segmental kyphosis decreased from 29.4 ± 14.1° to 7.9 ± 8.0° (p < 0.001). The neurologic function on the FS did not worsen in any and improved in four of the patients. The median KPS remained stable over the whole observation period (70% vs. 70%). Spinal fusion was observed in nine out of nine patients who received CT follow-up >120 days after index surgery. Conclusions: This study showed that pVCR is a safe surgical technique with few surgical complications and no neurological deterioration considering the cohort. The patients' segmental kyphosis and VAS improved significantly, while the KPS remained stable.

KW - Aged

KW - Aged, 80 and over

KW - Humans

KW - Kyphosis/etiology

KW - Lumbar Vertebrae/surgery

KW - Middle Aged

KW - Osteoporotic Fractures/surgery

KW - Retrospective Studies

KW - Spinal Fractures/surgery

KW - Spinal Fusion

KW - Spine/surgery

KW - Thoracic Vertebrae/surgery

KW - Treatment Outcome

UR - https://www.mdpi.com/1648-9144/58/2/277

U2 - 10.3390/medicina58020277

DO - 10.3390/medicina58020277

M3 - SCORING: Journal article

C2 - 35208600

VL - 58

JO - MEDICINA-LITHUANIA

JF - MEDICINA-LITHUANIA

SN - 1010-660X

IS - 2

M1 - 277

ER -