Osteosarcoma
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Osteosarcoma. / Eaton, Bree R; Schwarz, Rudolf; Vatner, Ralph; Yeh, Brian; Claude, Line; Indelicato, Daniel J; Laack, Nadia.
In: PEDIATR BLOOD CANCER, Vol. 68, No. S2, e28352, 05.2021.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - Osteosarcoma
AU - Eaton, Bree R
AU - Schwarz, Rudolf
AU - Vatner, Ralph
AU - Yeh, Brian
AU - Claude, Line
AU - Indelicato, Daniel J
AU - Laack, Nadia
N1 - © 2020 Wiley Periodicals, Inc.
PY - 2021/5
Y1 - 2021/5
N2 - Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This paper reviews the general management and standard radiotherapy guidelines for osteosarcoma in both North America and Europe in a joined effort between the Children's Oncology Group and International Society of Pediatric Oncology. Standard treatment involves multiagent induction chemotherapy followed by surgical resection for local tumor control and consolidation local control to metastatic sites. Radiotherapy is reserved for cases with a marginal or incomplete resection or for definitive treatment in the case of unresectable disease. We present supporting data for the role of chemotherapy, surgery, and radiation therapy.
AB - Osteosarcoma is a rare tumor that requires complex multidisciplinary management. This paper reviews the general management and standard radiotherapy guidelines for osteosarcoma in both North America and Europe in a joined effort between the Children's Oncology Group and International Society of Pediatric Oncology. Standard treatment involves multiagent induction chemotherapy followed by surgical resection for local tumor control and consolidation local control to metastatic sites. Radiotherapy is reserved for cases with a marginal or incomplete resection or for definitive treatment in the case of unresectable disease. We present supporting data for the role of chemotherapy, surgery, and radiation therapy.
KW - Bone Neoplasms/pathology
KW - Child
KW - Humans
KW - Osteosarcoma/pathology
KW - Prognosis
KW - Radiotherapy/methods
KW - Survival Rate
U2 - 10.1002/pbc.28352
DO - 10.1002/pbc.28352
M3 - SCORING: Review article
C2 - 32779875
VL - 68
JO - PEDIATR BLOOD CANCER
JF - PEDIATR BLOOD CANCER
SN - 1545-5009
IS - S2
M1 - e28352
ER -