Organ specific mouse head coil for improved image quality in magnetic particle imaging
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Organ specific mouse head coil for improved image quality in magnetic particle imaging. / Graeser, M.; Liebing, T.; Szwargulski, P.; Förger, F.; Thieben, F.; Ludewig, P.; Knopp, T.
In: Int J Magn Part Imag, Vol. 6, No. 2, 2009046, 2020.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
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TY - JOUR
T1 - Organ specific mouse head coil for improved image quality in magnetic particle imaging
AU - Graeser, M.
AU - Liebing, T.
AU - Szwargulski, P.
AU - Förger, F.
AU - Thieben, F.
AU - Ludewig, P.
AU - Knopp, T.
N1 - Publisher Copyright: © 2020 Graeser et al.; licensee Infinite Science Publishing GmbH.
PY - 2020
Y1 - 2020
N2 - Magnetic particle imaging is a very useful tool in the detection of stroke. To study the ability of stroke in a mouse model the data acquisition is challenging as a mouse brain contains only a very small ratio of blood compared to large animals or humans. The effective concentration within the whole organ is therefore very small, especially compared to the heart or the liver. Typical MPI receiver coils however cover a sensitive region of around 30 mm to 50 mm and have a bore size of above 40 mm. This leads on the one hand to non-optimal signal coupling due to the distance to the particles and on the other hand strong signals from the heart can cause artifacts in the low signal regions. In this work we present a coil optimized for mouse brain imaging, which due to its small size, also dampens signal from regions outside of the coil.
AB - Magnetic particle imaging is a very useful tool in the detection of stroke. To study the ability of stroke in a mouse model the data acquisition is challenging as a mouse brain contains only a very small ratio of blood compared to large animals or humans. The effective concentration within the whole organ is therefore very small, especially compared to the heart or the liver. Typical MPI receiver coils however cover a sensitive region of around 30 mm to 50 mm and have a bore size of above 40 mm. This leads on the one hand to non-optimal signal coupling due to the distance to the particles and on the other hand strong signals from the heart can cause artifacts in the low signal regions. In this work we present a coil optimized for mouse brain imaging, which due to its small size, also dampens signal from regions outside of the coil.
U2 - 10.18416/IJMPI.2020.2009046
DO - 10.18416/IJMPI.2020.2009046
M3 - Other (editorial matter etc.)
AN - SCOPUS:85090189621
VL - 6
JO - Int J Magn Part Imag
JF - Int J Magn Part Imag
SN - 2365-9033
IS - 2
M1 - 2009046
ER -
