Optische Diagnoseverfahren zur Tumorfrühdiagnostik im oberen Luft-Speise-Weg
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Optische Diagnoseverfahren zur Tumorfrühdiagnostik im oberen Luft-Speise-Weg : Quo vadis? / Betz, C S; Kraft, M; Arens, C; Schuster, M; Pfeffer, C; Rühm, A; Stepp, H; Englhard, A; Volgger, V.
In: HNO, Vol. 64, No. 1, 01.2016, p. 41-8.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - Optische Diagnoseverfahren zur Tumorfrühdiagnostik im oberen Luft-Speise-Weg
T2 - Quo vadis?
AU - Betz, C S
AU - Kraft, M
AU - Arens, C
AU - Schuster, M
AU - Pfeffer, C
AU - Rühm, A
AU - Stepp, H
AU - Englhard, A
AU - Volgger, V
PY - 2016/1
Y1 - 2016/1
N2 - BACKGROUND: Optical diagnostic methods may simplify and improve the early diagnosis of tumours of the upper aerodigestive tract; however, these have not yet found their way into clinical routine.OBJECTIVE: This article aims to define the problems that have prevented routine use of optical diagnostic methods so far, as well as listing and also explaining potential trendsetting approaches to overcome these difficulties.MATERIALS AND METHODS: The study is based on a combined analysis of publically accessible databases (PubMed MEDLINE, Thompson Reuters Web of Science, SPIE. Digital Library; full time period available; search strings: "oral cavity", "pharynx", "larnyx", "optical diagnosis", "optical biopsy", "optical coherence tomography", "confocal endomicroscopy", "fluorescence endoscopy", "narrow band imaging", "non-linear imaging", "fluorescence lifetime imaging"), as well as personal experiences.RESULTS: Both conceptual and methodical problems were determined, and possible solutions based on current developments are discussed.CONCLUSION: Optical diagnostic methods have the potential to revolutionise early diagnosis of upper aerodigestive tract malignancies, providing the different hurdles listed in this review can be overcome.
AB - BACKGROUND: Optical diagnostic methods may simplify and improve the early diagnosis of tumours of the upper aerodigestive tract; however, these have not yet found their way into clinical routine.OBJECTIVE: This article aims to define the problems that have prevented routine use of optical diagnostic methods so far, as well as listing and also explaining potential trendsetting approaches to overcome these difficulties.MATERIALS AND METHODS: The study is based on a combined analysis of publically accessible databases (PubMed MEDLINE, Thompson Reuters Web of Science, SPIE. Digital Library; full time period available; search strings: "oral cavity", "pharynx", "larnyx", "optical diagnosis", "optical biopsy", "optical coherence tomography", "confocal endomicroscopy", "fluorescence endoscopy", "narrow band imaging", "non-linear imaging", "fluorescence lifetime imaging"), as well as personal experiences.RESULTS: Both conceptual and methodical problems were determined, and possible solutions based on current developments are discussed.CONCLUSION: Optical diagnostic methods have the potential to revolutionise early diagnosis of upper aerodigestive tract malignancies, providing the different hurdles listed in this review can be overcome.
KW - Early Detection of Cancer
KW - Evidence-Based Medicine
KW - Forecasting
KW - Gastrointestinal Neoplasms
KW - Humans
KW - Precancerous Conditions
KW - Respiratory Tract Neoplasms
KW - Tomography, Optical
KW - Journal Article
KW - Review
U2 - 10.1007/s00106-015-0104-8
DO - 10.1007/s00106-015-0104-8
M3 - SCORING: Review
C2 - 26666558
VL - 64
SP - 41
EP - 48
JO - HNO
JF - HNO
SN - 0017-6192
IS - 1
ER -