Research ExplorerPublicationsOptimized mapping of slow pathway ablation guided by subthre...

Optimized mapping of slow pathway ablation guided by subthreshold stimulation

Standard

Optimized mapping of slow pathway ablation guided by subthreshold stimulation : a randomized prospective study in patients with recurrent atrioventricular nodal re-entrant tachycardia. / Willems, S; Weiss, C; Shenasa, M; Ventura, R; Hoffmann, M; Meinertz, T.

In: J AM COLL CARDIOL, Vol. 37, No. 6, 05.2001, p. 1645-50.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Willems, S, Weiss, C, Shenasa, M, Ventura, R, Hoffmann, M & Meinertz, T 2001, 'Optimized mapping of slow pathway ablation guided by subthreshold stimulation: a randomized prospective study in patients with recurrent atrioventricular nodal re-entrant tachycardia', J AM COLL CARDIOL, vol. 37, no. 6, pp. 1645-50. https://doi.org/10.1016/s0735-1097(01)01206-2

APA

Willems, S., Weiss, C., Shenasa, M., Ventura, R., Hoffmann, M., & Meinertz, T. (2001). Optimized mapping of slow pathway ablation guided by subthreshold stimulation: a randomized prospective study in patients with recurrent atrioventricular nodal re-entrant tachycardia. J AM COLL CARDIOL, 37(6), 1645-50. https://doi.org/10.1016/s0735-1097(01)01206-2

Vancouver

Willems S, Weiss C, Shenasa M, Ventura R, Hoffmann M, Meinertz T. Optimized mapping of slow pathway ablation guided by subthreshold stimulation: a randomized prospective study in patients with recurrent atrioventricular nodal re-entrant tachycardia. J AM COLL CARDIOL. 2001 May;37(6):1645-50. https://doi.org/10.1016/s0735-1097(01)01206-2

Bibtex

@article{33ed8709e8b74987b3f9929a9e2b887c,
title = "Optimized mapping of slow pathway ablation guided by subthreshold stimulation: a randomized prospective study in patients with recurrent atrioventricular nodal re-entrant tachycardia",
abstract = "OBJECTIVES: This randomized prospective study sought to assess the value of slow pathway (SP) mapping and ablation guided by subthreshold stimulation (STS) in comparison with a strategy based on conventional criteria.BACKGROUND: Previous studies have demonstrated that STS can be used as a highly specific and sensitive marker for successful SP ablation in the setting of atrioventricular nodal re-entrant tachycardia (AVNRT). Nonetheless, thus far this mapping strategy has not been investigated in contrast with the conventional approach.METHODS: One hundred patients with sustained AVNRT were included. Fifty patients (group A) were randomly assigned to endocardial mapping and SP ablation using currently established criteria. In the other 50 patients (group B), SP ablation was guided by STS mapping. In group B patients, only radiofrequency current (RFC) was applied if additionally constant current STS (up to 5 mA) during AVNRT interrupted the tachycardia due to selective block within the SP.RESULTS: Termination of AVNRT without apparent capture was observed during STS in 47 of 50 group B patients (94%). In all cases, this effect was indicative for successful subsequent SP ablation. The mean number of RFC pulses required for successful SP ablation was significantly lower in patients assigned to the STS-guided strategy (1.6 +/- 1.3 vs. 3.9 +/- 3.4; p = 0.0003). Similarly, the mean procedure duration was shorter in the STS group (156.9 +/- 33.5 vs. 173.2 +/- 49.7 min; p = 0.0221); the fluoroscopy time was comparable between both groups (14.1 +/- 8.7 vs. 16.9 +/- 10.6 min; p = 0.1278).CONCLUSIONS: Subthreshold stimulation is an effective method for detection of target sites for selective SP ablation. This technique helps to minimize the number of RFC pulses without prolongation of the overall procedure and fluoroscopy time required for SP ablation.",
keywords = "Aged, Electrophysiologic Techniques, Cardiac/methods, Female, Fluoroscopy/methods, Heart Conduction System/surgery, Humans, Male, Middle Aged, Prospective Studies, Radiography, Interventional/methods, Recurrence, Sensitivity and Specificity, Tachycardia, Atrioventricular Nodal Reentry/diagnosis, Time Factors, Treatment Outcome",
author = "S Willems and C Weiss and M Shenasa and R Ventura and M Hoffmann and T Meinertz",
year = "2001",
month = may,
doi = "10.1016/s0735-1097(01)01206-2",
language = "English",
volume = "37",
pages = "1645--50",
journal = "J AM COLL CARDIOL",
issn = "0735-1097",
publisher = "Elsevier USA",
number = "6",

}

RIS

TY - JOUR

T1 - Optimized mapping of slow pathway ablation guided by subthreshold stimulation

T2 - a randomized prospective study in patients with recurrent atrioventricular nodal re-entrant tachycardia

AU - Willems, S

AU - Weiss, C

AU - Shenasa, M

AU - Ventura, R

AU - Hoffmann, M

AU - Meinertz, T

PY - 2001/5

Y1 - 2001/5

N2 - OBJECTIVES: This randomized prospective study sought to assess the value of slow pathway (SP) mapping and ablation guided by subthreshold stimulation (STS) in comparison with a strategy based on conventional criteria.BACKGROUND: Previous studies have demonstrated that STS can be used as a highly specific and sensitive marker for successful SP ablation in the setting of atrioventricular nodal re-entrant tachycardia (AVNRT). Nonetheless, thus far this mapping strategy has not been investigated in contrast with the conventional approach.METHODS: One hundred patients with sustained AVNRT were included. Fifty patients (group A) were randomly assigned to endocardial mapping and SP ablation using currently established criteria. In the other 50 patients (group B), SP ablation was guided by STS mapping. In group B patients, only radiofrequency current (RFC) was applied if additionally constant current STS (up to 5 mA) during AVNRT interrupted the tachycardia due to selective block within the SP.RESULTS: Termination of AVNRT without apparent capture was observed during STS in 47 of 50 group B patients (94%). In all cases, this effect was indicative for successful subsequent SP ablation. The mean number of RFC pulses required for successful SP ablation was significantly lower in patients assigned to the STS-guided strategy (1.6 +/- 1.3 vs. 3.9 +/- 3.4; p = 0.0003). Similarly, the mean procedure duration was shorter in the STS group (156.9 +/- 33.5 vs. 173.2 +/- 49.7 min; p = 0.0221); the fluoroscopy time was comparable between both groups (14.1 +/- 8.7 vs. 16.9 +/- 10.6 min; p = 0.1278).CONCLUSIONS: Subthreshold stimulation is an effective method for detection of target sites for selective SP ablation. This technique helps to minimize the number of RFC pulses without prolongation of the overall procedure and fluoroscopy time required for SP ablation.

AB - OBJECTIVES: This randomized prospective study sought to assess the value of slow pathway (SP) mapping and ablation guided by subthreshold stimulation (STS) in comparison with a strategy based on conventional criteria.BACKGROUND: Previous studies have demonstrated that STS can be used as a highly specific and sensitive marker for successful SP ablation in the setting of atrioventricular nodal re-entrant tachycardia (AVNRT). Nonetheless, thus far this mapping strategy has not been investigated in contrast with the conventional approach.METHODS: One hundred patients with sustained AVNRT were included. Fifty patients (group A) were randomly assigned to endocardial mapping and SP ablation using currently established criteria. In the other 50 patients (group B), SP ablation was guided by STS mapping. In group B patients, only radiofrequency current (RFC) was applied if additionally constant current STS (up to 5 mA) during AVNRT interrupted the tachycardia due to selective block within the SP.RESULTS: Termination of AVNRT without apparent capture was observed during STS in 47 of 50 group B patients (94%). In all cases, this effect was indicative for successful subsequent SP ablation. The mean number of RFC pulses required for successful SP ablation was significantly lower in patients assigned to the STS-guided strategy (1.6 +/- 1.3 vs. 3.9 +/- 3.4; p = 0.0003). Similarly, the mean procedure duration was shorter in the STS group (156.9 +/- 33.5 vs. 173.2 +/- 49.7 min; p = 0.0221); the fluoroscopy time was comparable between both groups (14.1 +/- 8.7 vs. 16.9 +/- 10.6 min; p = 0.1278).CONCLUSIONS: Subthreshold stimulation is an effective method for detection of target sites for selective SP ablation. This technique helps to minimize the number of RFC pulses without prolongation of the overall procedure and fluoroscopy time required for SP ablation.

KW - Aged

KW - Electrophysiologic Techniques, Cardiac/methods

KW - Female

KW - Fluoroscopy/methods

KW - Heart Conduction System/surgery

KW - Humans

KW - Male

KW - Middle Aged

KW - Prospective Studies

KW - Radiography, Interventional/methods

KW - Recurrence

KW - Sensitivity and Specificity

KW - Tachycardia, Atrioventricular Nodal Reentry/diagnosis

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1016/s0735-1097(01)01206-2

DO - 10.1016/s0735-1097(01)01206-2

M3 - SCORING: Journal article

C2 - 11345379

VL - 37

SP - 1645

EP - 1650

JO - J AM COLL CARDIOL

JF - J AM COLL CARDIOL

SN - 0735-1097

IS - 6

ER -