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Open Versus Robotic Cystectomy

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Open Versus Robotic Cystectomy : A Propensity Score Matched Analysis Comparing Survival Outcomes. / Moschini, Marco; Zamboni, Stefania; Soria, Francesco; Mathieu, Romain; Xylinas, Evanguelos; Tan, Wei Shen; Kelly, John D; Simone, Giuseppe; Meraney, Anoop; Krishna, Suprita; Konety, Badrinath; Mattei, Agostino; Baumeister, Philipp; Mordasini, Livio; Montorsi, Francesco; Briganti, Alberto; Gallina, Andrea; Stabile, Armando; Sanchez-Salas, Rafael; Cathelineau, Xavier; Rink, Michael; Necchi, Andrea; Karakiewicz, Pierre I; Rouprêt, Morgan; Koupparis, Anthony; Kassouf, Wassim; Scherr, Douglas S; Ploussard, Guillaume; Boorjian, Stephen A; Lotan, Yair; Sooriakumaran, Prasanna; Shariat, Shahrokh F.

In: J CLIN MED, Vol. 8, No. 8, 09.08.2019.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Moschini, M, Zamboni, S, Soria, F, Mathieu, R, Xylinas, E, Tan, WS, Kelly, JD, Simone, G, Meraney, A, Krishna, S, Konety, B, Mattei, A, Baumeister, P, Mordasini, L, Montorsi, F, Briganti, A, Gallina, A, Stabile, A, Sanchez-Salas, R, Cathelineau, X, Rink, M, Necchi, A, Karakiewicz, PI, Rouprêt, M, Koupparis, A, Kassouf, W, Scherr, DS, Ploussard, G, Boorjian, SA, Lotan, Y, Sooriakumaran, P & Shariat, SF 2019, 'Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes', J CLIN MED, vol. 8, no. 8. https://doi.org/10.3390/jcm8081192

APA

Moschini, M., Zamboni, S., Soria, F., Mathieu, R., Xylinas, E., Tan, W. S., Kelly, J. D., Simone, G., Meraney, A., Krishna, S., Konety, B., Mattei, A., Baumeister, P., Mordasini, L., Montorsi, F., Briganti, A., Gallina, A., Stabile, A., Sanchez-Salas, R., ... Shariat, S. F. (2019). Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes. J CLIN MED, 8(8). https://doi.org/10.3390/jcm8081192

Vancouver

Moschini M, Zamboni S, Soria F, Mathieu R, Xylinas E, Tan WS et al. Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes. J CLIN MED. 2019 Aug 9;8(8). https://doi.org/10.3390/jcm8081192

Bibtex

@article{fee86c5b160d4c7c82a2850c8bdc7132,
title = "Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes",
abstract = "BACKGROUND: To assess the differential effect of robotic assisted radical cystectomy (RARC) versus open radical cystectomy (ORC) on survival outcomes in matched analyses performed on a large multicentric cohort.METHODS: The study included 9757 patients with urothelial bladder cancer (BCa) treated in a consecutive manner at each of 25 institutions. All patients underwent radical cystectomy with bilateral pelvic lymphadenectomy. To adjust for potential selection bias, propensity score matching 2:1 was performed with two ORC patients matched to one RARC patient. The propensity-matched cohort included 1374 patients. Multivariable competing risk analyses accounting for death of other causes, tested association of surgical technique with recurrence and cancer specific mortality (CSM), before and after propensity score matching.RESULTS: Overall, 767 (7.8%) patients underwent RARC and 8990 (92.2%) ORC. The median follow-up before and after propensity matching was 81 and 102 months, respectively. In the overall population, the 3-year recurrence rates and CSM were 37% vs. 26% and 34% vs. 24% for ORC vs. RARC (all p values > 0.1), respectively. On multivariable Cox regression analyses, RARC and ORC had similar recurrence and CSM rates before and after matching (all p values > 0.1).CONCLUSIONS: Patients treated with RARC and ORC have similar survival outcomes. This data is helpful in consulting patients until long term survival outcomes of level one evidence is available.",
author = "Marco Moschini and Stefania Zamboni and Francesco Soria and Romain Mathieu and Evanguelos Xylinas and Tan, {Wei Shen} and Kelly, {John D} and Giuseppe Simone and Anoop Meraney and Suprita Krishna and Badrinath Konety and Agostino Mattei and Philipp Baumeister and Livio Mordasini and Francesco Montorsi and Alberto Briganti and Andrea Gallina and Armando Stabile and Rafael Sanchez-Salas and Xavier Cathelineau and Michael Rink and Andrea Necchi and Karakiewicz, {Pierre I} and Morgan Roupr{\^e}t and Anthony Koupparis and Wassim Kassouf and Scherr, {Douglas S} and Guillaume Ploussard and Boorjian, {Stephen A} and Yair Lotan and Prasanna Sooriakumaran and Shariat, {Shahrokh F}",
year = "2019",
month = aug,
day = "9",
doi = "10.3390/jcm8081192",
language = "English",
volume = "8",
journal = "J CLIN MED",
issn = "2077-0383",
publisher = "MDPI AG",
number = "8",

}

RIS

TY - JOUR

T1 - Open Versus Robotic Cystectomy

T2 - A Propensity Score Matched Analysis Comparing Survival Outcomes

AU - Moschini, Marco

AU - Zamboni, Stefania

AU - Soria, Francesco

AU - Mathieu, Romain

AU - Xylinas, Evanguelos

AU - Tan, Wei Shen

AU - Kelly, John D

AU - Simone, Giuseppe

AU - Meraney, Anoop

AU - Krishna, Suprita

AU - Konety, Badrinath

AU - Mattei, Agostino

AU - Baumeister, Philipp

AU - Mordasini, Livio

AU - Montorsi, Francesco

AU - Briganti, Alberto

AU - Gallina, Andrea

AU - Stabile, Armando

AU - Sanchez-Salas, Rafael

AU - Cathelineau, Xavier

AU - Rink, Michael

AU - Necchi, Andrea

AU - Karakiewicz, Pierre I

AU - Rouprêt, Morgan

AU - Koupparis, Anthony

AU - Kassouf, Wassim

AU - Scherr, Douglas S

AU - Ploussard, Guillaume

AU - Boorjian, Stephen A

AU - Lotan, Yair

AU - Sooriakumaran, Prasanna

AU - Shariat, Shahrokh F

PY - 2019/8/9

Y1 - 2019/8/9

N2 - BACKGROUND: To assess the differential effect of robotic assisted radical cystectomy (RARC) versus open radical cystectomy (ORC) on survival outcomes in matched analyses performed on a large multicentric cohort.METHODS: The study included 9757 patients with urothelial bladder cancer (BCa) treated in a consecutive manner at each of 25 institutions. All patients underwent radical cystectomy with bilateral pelvic lymphadenectomy. To adjust for potential selection bias, propensity score matching 2:1 was performed with two ORC patients matched to one RARC patient. The propensity-matched cohort included 1374 patients. Multivariable competing risk analyses accounting for death of other causes, tested association of surgical technique with recurrence and cancer specific mortality (CSM), before and after propensity score matching.RESULTS: Overall, 767 (7.8%) patients underwent RARC and 8990 (92.2%) ORC. The median follow-up before and after propensity matching was 81 and 102 months, respectively. In the overall population, the 3-year recurrence rates and CSM were 37% vs. 26% and 34% vs. 24% for ORC vs. RARC (all p values > 0.1), respectively. On multivariable Cox regression analyses, RARC and ORC had similar recurrence and CSM rates before and after matching (all p values > 0.1).CONCLUSIONS: Patients treated with RARC and ORC have similar survival outcomes. This data is helpful in consulting patients until long term survival outcomes of level one evidence is available.

AB - BACKGROUND: To assess the differential effect of robotic assisted radical cystectomy (RARC) versus open radical cystectomy (ORC) on survival outcomes in matched analyses performed on a large multicentric cohort.METHODS: The study included 9757 patients with urothelial bladder cancer (BCa) treated in a consecutive manner at each of 25 institutions. All patients underwent radical cystectomy with bilateral pelvic lymphadenectomy. To adjust for potential selection bias, propensity score matching 2:1 was performed with two ORC patients matched to one RARC patient. The propensity-matched cohort included 1374 patients. Multivariable competing risk analyses accounting for death of other causes, tested association of surgical technique with recurrence and cancer specific mortality (CSM), before and after propensity score matching.RESULTS: Overall, 767 (7.8%) patients underwent RARC and 8990 (92.2%) ORC. The median follow-up before and after propensity matching was 81 and 102 months, respectively. In the overall population, the 3-year recurrence rates and CSM were 37% vs. 26% and 34% vs. 24% for ORC vs. RARC (all p values > 0.1), respectively. On multivariable Cox regression analyses, RARC and ORC had similar recurrence and CSM rates before and after matching (all p values > 0.1).CONCLUSIONS: Patients treated with RARC and ORC have similar survival outcomes. This data is helpful in consulting patients until long term survival outcomes of level one evidence is available.

U2 - 10.3390/jcm8081192

DO - 10.3390/jcm8081192

M3 - SCORING: Journal article

C2 - 31395826

VL - 8

JO - J CLIN MED

JF - J CLIN MED

SN - 2077-0383

IS - 8

ER -