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Oncological outcome after radical prostatectomy: Marital status does not make a difference

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Oncological outcome after radical prostatectomy: Marital status does not make a difference. / Schiffmann, Jonas; Beyer, Burkhard; Tennstedt, Pierre; Boehm, Katharina; Mehring, Gisa; Schlomm, Thorsten; Salomon, Georg; Karakiewicz, Pierre; Graefen, Markus.

In: INT J UROL, Vol. 22, No. 5, 17.03.2015, p. 484-489.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schiffmann, J, Beyer, B, Tennstedt, P, Boehm, K, Mehring, G, Schlomm, T, Salomon, G, Karakiewicz, P & Graefen, M 2015, 'Oncological outcome after radical prostatectomy: Marital status does not make a difference', INT J UROL, vol. 22, no. 5, pp. 484-489. https://doi.org/10.1111/iju.12717

APA

Schiffmann, J., Beyer, B., Tennstedt, P., Boehm, K., Mehring, G., Schlomm, T., Salomon, G., Karakiewicz, P., & Graefen, M. (2015). Oncological outcome after radical prostatectomy: Marital status does not make a difference. INT J UROL, 22(5), 484-489. https://doi.org/10.1111/iju.12717

Vancouver

Schiffmann J, Beyer B, Tennstedt P, Boehm K, Mehring G, Schlomm T et al. Oncological outcome after radical prostatectomy: Marital status does not make a difference. INT J UROL. 2015 Mar 17;22(5):484-489. https://doi.org/10.1111/iju.12717

Bibtex

@article{06546bf75f48477c9aa1f01b5fba6318,
title = "Oncological outcome after radical prostatectomy: Marital status does not make a difference",
abstract = "OBJECTIVES: To examine the impact of marital status on prostate cancer characteristics at radical prostatectomy and oncological outcome after surgery at a high-volume center.METHODS: We relied on the Martini-Clinic Prostate Cancer database and investigated 8088 prostate cancer patients treated with radical prostatectomy between January 2000 and March 2011. We analyzed differences in clinical and pathological characteristics according to marital status (married and partnership vs single). Additionally, we relied on multivariable Cox regression analyses to predict biochemical recurrence, metastases and death after radical prostatectomy. Finally, Kaplan-Meier analyses were used in a propensity score-matched cohort, adjusted for clinical and pathological characteristics, to examine differences in biochemical recurrence-free, metastases-free and overall survival according to marital status.RESULTS: According to marital status, no significant differences were recorded within clinical and pathological characteristics (all P > 0.05). The impact of marital status on biochemical recurrence (hazard ratio 1.0, 95% confidence interval 0.9-1.3, P = 0.7), metastases (hazard ratio 1.3, 95% confidence interval 0.8-2.1, P = 0.3) and death (hazard ratio 0.8, 95% confidence interval 0.4-1.6, P = 0.6) after radical prostatectomy was not significant (median follow up 48 months). Kaplan-Meier analyses recorded no significant differences for biochemical recurrence-free, metastases-free and overall survival (all log-rank P > 0.05) according to marital status.CONCLUSIONS: Marital status does not affect the clinical and pathological characteristics of radical prostatectomy patients treated at a high-volume center. Furthermore, marital status does not affect biochemical recurrence-free and metastases-free survival after radical prostatectomy.",
author = "Jonas Schiffmann and Burkhard Beyer and Pierre Tennstedt and Katharina Boehm and Gisa Mehring and Thorsten Schlomm and Georg Salomon and Pierre Karakiewicz and Markus Graefen",
note = "{\textcopyright} 2015 The Japanese Urological Association.",
year = "2015",
month = mar,
day = "17",
doi = "10.1111/iju.12717",
language = "English",
volume = "22",
pages = "484--489",
journal = "INT J UROL",
issn = "0919-8172",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Oncological outcome after radical prostatectomy: Marital status does not make a difference

AU - Schiffmann, Jonas

AU - Beyer, Burkhard

AU - Tennstedt, Pierre

AU - Boehm, Katharina

AU - Mehring, Gisa

AU - Schlomm, Thorsten

AU - Salomon, Georg

AU - Karakiewicz, Pierre

AU - Graefen, Markus

N1 - © 2015 The Japanese Urological Association.

PY - 2015/3/17

Y1 - 2015/3/17

N2 - OBJECTIVES: To examine the impact of marital status on prostate cancer characteristics at radical prostatectomy and oncological outcome after surgery at a high-volume center.METHODS: We relied on the Martini-Clinic Prostate Cancer database and investigated 8088 prostate cancer patients treated with radical prostatectomy between January 2000 and March 2011. We analyzed differences in clinical and pathological characteristics according to marital status (married and partnership vs single). Additionally, we relied on multivariable Cox regression analyses to predict biochemical recurrence, metastases and death after radical prostatectomy. Finally, Kaplan-Meier analyses were used in a propensity score-matched cohort, adjusted for clinical and pathological characteristics, to examine differences in biochemical recurrence-free, metastases-free and overall survival according to marital status.RESULTS: According to marital status, no significant differences were recorded within clinical and pathological characteristics (all P > 0.05). The impact of marital status on biochemical recurrence (hazard ratio 1.0, 95% confidence interval 0.9-1.3, P = 0.7), metastases (hazard ratio 1.3, 95% confidence interval 0.8-2.1, P = 0.3) and death (hazard ratio 0.8, 95% confidence interval 0.4-1.6, P = 0.6) after radical prostatectomy was not significant (median follow up 48 months). Kaplan-Meier analyses recorded no significant differences for biochemical recurrence-free, metastases-free and overall survival (all log-rank P > 0.05) according to marital status.CONCLUSIONS: Marital status does not affect the clinical and pathological characteristics of radical prostatectomy patients treated at a high-volume center. Furthermore, marital status does not affect biochemical recurrence-free and metastases-free survival after radical prostatectomy.

AB - OBJECTIVES: To examine the impact of marital status on prostate cancer characteristics at radical prostatectomy and oncological outcome after surgery at a high-volume center.METHODS: We relied on the Martini-Clinic Prostate Cancer database and investigated 8088 prostate cancer patients treated with radical prostatectomy between January 2000 and March 2011. We analyzed differences in clinical and pathological characteristics according to marital status (married and partnership vs single). Additionally, we relied on multivariable Cox regression analyses to predict biochemical recurrence, metastases and death after radical prostatectomy. Finally, Kaplan-Meier analyses were used in a propensity score-matched cohort, adjusted for clinical and pathological characteristics, to examine differences in biochemical recurrence-free, metastases-free and overall survival according to marital status.RESULTS: According to marital status, no significant differences were recorded within clinical and pathological characteristics (all P > 0.05). The impact of marital status on biochemical recurrence (hazard ratio 1.0, 95% confidence interval 0.9-1.3, P = 0.7), metastases (hazard ratio 1.3, 95% confidence interval 0.8-2.1, P = 0.3) and death (hazard ratio 0.8, 95% confidence interval 0.4-1.6, P = 0.6) after radical prostatectomy was not significant (median follow up 48 months). Kaplan-Meier analyses recorded no significant differences for biochemical recurrence-free, metastases-free and overall survival (all log-rank P > 0.05) according to marital status.CONCLUSIONS: Marital status does not affect the clinical and pathological characteristics of radical prostatectomy patients treated at a high-volume center. Furthermore, marital status does not affect biochemical recurrence-free and metastases-free survival after radical prostatectomy.

U2 - 10.1111/iju.12717

DO - 10.1111/iju.12717

M3 - SCORING: Journal article

C2 - 25781055

VL - 22

SP - 484

EP - 489

JO - INT J UROL

JF - INT J UROL

SN - 0919-8172

IS - 5

ER -